Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yean Kee, Lee"'
Autor:
Xin-Yi Tien1, Yean Kee Lee2,3,4, Pooi-Fong Wong1 wongpf@um.edu.my, Yi-Sheng Khor1, Murugan, Dharmani Devi1, Abdullah, Iskandar2,3,4 iskandar.a@um.edu.my
Publikováno v:
Drug Discoveries & Therapeutics. Jun2024, Vol. 18 Issue 3, p199-206. 8p.
Autor:
Cheok Wui Chee, Nor Hisam Zamakshshari, Vannajan Sanghiran Lee, Iskandar Abdullah, Rozana Othman, Yean Kee Lee, Najihah Mohd Hashim, Nurshamimi Nor Rashid
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270970 (2022)
There is an increasing demand in developing new, effective, and affordable anti-cancer against colon and rectal. In this study, our aim is to identify the potential anthraquinone compounds from the root bark of Morinda citrifolia to be tested in vitr
Externí odkaz:
https://doaj.org/article/b540536d2ca84cbc821f7c85819c36fd
Publikováno v:
Marine Drugs, Vol 20, Iss 9, p 579 (2022)
A marine natural product possesses a diverse and unique scaffold that contributes to a vast array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine natural products. These rare skeletons exhibit a wide range
Externí odkaz:
https://doaj.org/article/88591b1287b747ca9db1ecd5cf782c2c
Publikováno v:
PeerJ, Vol 8, p e9094 (2020)
Flavonoids and prenylated flavonoids are active components in medicinal plant extracts which exhibit beneficial effects on human health. Prenylated flavonoids consist of a flavonoid core with a prenyl group attached to it. This prenylation process is
Externí odkaz:
https://doaj.org/article/7fa641a03c014ad8b496a61075941972
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 2, Pp 91-95 (2017)
Objective: To investigate the antiviral property of a lead ligand, YK51 that was synthesized based on the flavanoid of a natural product toward dengue virus type-2 (DENV2) replication. Methods: cRNA was isolated from HepG2 cells inoculated with 1000
Externí odkaz:
https://doaj.org/article/2f404171904f4a3f9dab8a4ddd4d08b1
Autor:
Chin Fei Chee, Nurhaliza Wati Mekzali, Cheok Wui Chee, Iskandar Abdullah, Yean Kee Lee, Nurshamimi Nor Rashid, Vannajan Sanghiran Lee, Rozana Othman, Najihah Mohd Hashim
Publikováno v:
Medicinal Chemistry. 19
Background: KRAS and p53 are two of the most common genetic alterations associated with colorectal cancer. New drug development targeting these mutated genes in colorectal cancer may serve as a potential treatment avenue to the current regimen. Objec
Autor:
Wei-Lian Tan, Yean Kee Lee, Yen Fong Ho, Rohana Yusof, Noorsaadah Abdul Rahman, Saiful Anuar Karsani
Publikováno v:
PeerJ, Vol 5, p e3939 (2018)
Dengue is endemic throughout tropical and subtropical regions of the world. Currently, there is no clinically approved therapeutic drug available for this acute viral infection. Although the first dengue vaccine Dengvaxia has been approved for use in
Externí odkaz:
https://doaj.org/article/277cbcf693ed4fb0a90d97862b47e779
Autor:
Noorsaadah Abd Rahman, Yean Kee Lee, Ramu Meesala, Iskandar Abdullah, Mohd Nizam Mordi, Ahmad Saifuddin Mohamad Arshad
Publikováno v:
Synlett. 31:2054-2058
A facile synthesis of various 2-(carbazolyl)benzothiazoles has been developed by one-pot CuBr-catalyzed three-component reactions of 2-iodoanilines, arylaldehydes, and elemental sulfur. Unlike traditional approach, this reaction exhibited a good func
Autor:
Cheok Wui Chee, Nor Hisam Zamakshshari, Vannajan Sanghiran Lee, Iskandar Abdullah, Rozana Othman, Yean Kee Lee, Najihah Mohd Hashim, Nurshamimi Nor Rashid
Publikováno v:
PloS one. 17(7)
There is an increasing demand in developing new, effective, and affordable anti-cancer against colon and rectal. In this study, our aim is to identify the potential anthraquinone compounds from the root bark of Morinda citrifolia to be tested in vitr
Publikováno v:
Mapana - Journal of Sciences. 18:21-28
A variety of flavanones and azaflavanones have been synthesised from chalcones, catalysed by 30 mol% solid support proline terminal peptide, which is mildly efficient with high conversions yields and could be recycled up to three times without signif