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Transglutaminase 1 Replacement Therapy Successfully Mitigates the Autosomal Recessive Congenital Ichthyosis Phenotype in Full-Thickness Skin Disease Equivalents

Autor: Plank, Roswitha, Yealland, Guy, Miceli, Enrico, Lima Cunha, Dulce, Graff, Patrick, Thomforde, Sari, Gruber, Robert, Moosbrugger-Martinz, Verena, Eckl, Katja, Calderón, Marcelo, Hennies, Hans Christian, Hedtrich, Sarah

Publikováno v: In Journal of Investigative Dermatology May 2019 139(5):1191-1195

Breaking the Barrier - Potent Anti-Inflammatory Activity following Efficient Topical Delivery of Etanercept using Thermoresponsive Nanogels

Autor: Giulbudagian, Michael, Yealland, Guy, Hönzke, Stefan, Edlich, Alexander, Geisendörfer, Birte, Kleuser, Burkhard, Hedtrich, Sarah, Calderón, Marcelo

Topical administration permits targeted, sustained delivery of therapeutics to human skin. Delivery to the skin, however, is typically limited to lipophilic molecules with molecular weight of < 500 Da, capable of crossing the stratum corneum. Neverth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc910643e36e1b6c94bf0244d3dc50da
http://www.thno.org/v08p0450.htm

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Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells.

Autor: Gerecke C; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Schumacher F; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany., Edlich A; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Wetzel A; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Yealland G; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Neubert LK; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Scholtka B; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Homann T; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany., Kleuser B; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.; NutriAct - Competence Cluster Nutrition Research Berlin-Potsdam, Germany.

Publikováno v: Oncotarget [Oncotarget] 2018 Aug 28; Vol. 9 (67), pp. 32822-32840. Date of Electronic Publication: 2018 Aug 28 (Print Publication: 2018).