Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yea Woon Kim"'
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8beb7b910561122e1a75be66f4e412
https://doi.org/10.1096/fj.202201891r
https://doi.org/10.1096/fj.202201891r
Publikováno v:
The FASEB Journal. 34:14736-14749
CCCTC-binding factor (CTCF) sites interact with each other in the chromatin environment, establishing chromatin domains. Our previous study showed that interaction between CTCF sites is cell type-specific around the β-globin locus and is dependent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fc95de59cee287a69cb54a40cc7f22
https://doi.org/10.1096/fj.202001526r
https://doi.org/10.1096/fj.202001526r
Publikováno v:
Biochemistry and Cell Biology. 97:380-386
Leukemia/lymphoma-related factor (LRF; a hematopoietic transcription factor) has been suggested to repress fetal γ-globin genes in the human adult stage β-globin locus. Here, to study the role of LRF in the fetal stage β-globin locus, we knocked o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73794c3a5224cb743f9755b976954525
https://doi.org/10.1139/bcb-2018-0303
https://doi.org/10.1139/bcb-2018-0303
Publikováno v:
The FASEB Journal. 35
Histone H3K4me1 and H3K27ac are enhancer-specific modifications and are required for enhancers to activate transcription of target genes. However, the reciprocal effects of these histone modifications on each other and their roles in enhancers are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66b9527410994294d1a3050c2537db8
https://doi.org/10.1096/fj.202100488r
https://doi.org/10.1096/fj.202100488r
Publikováno v:
The FASEB Journal. 35
Insulators are cis-regulatory elements that block enhancer activity and prevent heterochromatin spreading. The binding of CCCTC-binding factor (CTCF) protein is essential for insulators to play the roles in a chromatin context. The β-globin locus, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df87dff741a3013f5b2440f55ea7977b
https://doi.org/10.1096/fj.202100105rr
https://doi.org/10.1096/fj.202100105rr
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(6)
The human β-globin locus control region (LCR) hypersensitive site 2 (HS2) is one of enhancers for transcription of the β-like globin genes in erythroid cells. Our previous study showed that the LCR HS2 has active chromatin structure before transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bd1bbbd044ca69029e8f68fd5f63f8
https://pubmed.ncbi.nlm.nih.gov/34033138
https://pubmed.ncbi.nlm.nih.gov/34033138
Histone H3K4me1 and H3K27ac are enhancer specific modifications and are required for enhancers to activate transcription of target genes. However the reciprocal effects of these histone modifications on each other and their roles in enhancers are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00f1d4f2fc2193a3f7cede0b9a75f4b8
https://doi.org/10.1101/2021.01.05.425373
https://doi.org/10.1101/2021.01.05.425373
CTCF sites interact with each other in the chromatin environment, establishing domains. Our previous study showed that interaction between CTCF sites is cell type-specific around the β-globin locus and is dependent on erythroid specific activator GA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fd87062d906e5da430bd945b0580b1
https://doi.org/10.1101/2020.05.14.095547
https://doi.org/10.1101/2020.05.14.095547
Autor:
Jae-Hoon Lee, Yea Woon Kim, Bum-Joon Park, Kim Ae-Ri, Youngmi Jung, Bomi Kwak, Eungyoung Kim, Ho-Jin Shin, Jee-Yeong Jeong, Dae-Kyu Song, Ah-Young Oh, Jehyun Nam, Inmyoung Park, Min Ji Ko, Sang-Woo Kim, Yun-Han Lee, Dong Uk Kim, Hokeun Sun
Publikováno v:
Leukemia. 33(12)
A large body of evidence suggests that B-cell lymphomas with enhanced Myc expression are associated with an aggressive phenotype and poor prognosis, which makes Myc a compelling therapeutic target. Phosphodiesterase 4B (PDE4B), a main hydrolyzer of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb6f050ad69087b8c6e0ffcc58ea40c
https://pubmed.ncbi.nlm.nih.gov/31138843
https://pubmed.ncbi.nlm.nih.gov/31138843
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms.
Histone variants H3.3 and H2A.Z are often enriched in enhancers and transcriptionally active genes. However, the incorporation dynamics of these variants and the mechanisms of their incorporation are unclear. Here, we examined the distribution of H3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2338c4165c0d6a5bb8634977861b2902
https://pubmed.ncbi.nlm.nih.gov/29879504
https://pubmed.ncbi.nlm.nih.gov/29879504