Zobrazeno 1 - 10
of 32
pro vyhledávání: '"YeQing Pi"'
Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury
Autor:
Justin R. Piro, Georgette L. Suidan, Jie Quan, YeQing Pi, Sharon M. O’Neill, Marissa Ilardi, Nikolay Pozdnyakov, Thomas A. Lanz, Hualin Xi, Robert D. Bell, Tarek A. Samad
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Acute neurological insults caused by infection, systemic inflammation, ischemia, or traumatic injury are often associated with breakdown of the blood-brain barrier (BBB) followed by infiltration of peripheral immune cells, cytotox
Externí odkaz:
https://doaj.org/article/0481b9a2d34f41619984e7c612e1c01e
Autor:
Justin R. Piro, Daniel I. Benjamin, James M. Duerr, YeQing Pi, Cathleen Gonzales, Kathleen M. Wood, Joel W. Schwartz, Daniel K. Nomura, Tarek A. Samad
Publikováno v:
Cell Reports, Vol 1, Iss 6, Pp 617-623 (2012)
Although inflammation in the brain is meant as a defense mechanism against neurotoxic stimuli, increasing evidence suggests that uncontrolled, chronic, and persistent inflammation contributes to neurodegeneration. Most neurodegenerative diseases have
Externí odkaz:
https://doaj.org/article/f1b504b3e54442e2b36634e16abc72f7
Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury
Autor:
Georgette L. Suidan, Thomas A. Lanz, YeQing Pi, Jie Quan, Justin R. Piro, Hualin Xi, Robert D. Bell, Tarek A. Samad, Sharon M. O’Neill, Marissa Ilardi, Nikolay Pozdnyakov
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Background Acute neurological insults caused by infection, systemic inflammation, ischemia, or traumatic injury are often associated with breakdown of the blood-brain barrier (BBB) followed by infiltration of peripheral immune cells, cytotoxic protei
Autor:
Kathleen M. Wood, Cathleen Gonzales, James M. Duerr, Joel W. Schwartz, Justin R. Piro, Daniel K. Nomura, Tarek A. Samad, Daniel I. Benjamin, YeQing Pi
Publikováno v:
Cell Reports, Vol 1, Iss 6, Pp 617-623 (2012)
Although inflammation in the brain is meant as a defense mechanism against neurotoxic stimuli, increasing evidence suggests that uncontrolled, chronic and persistent inflammation contributes to neurodegeneration. Most neurodegenerative diseases have
Publikováno v:
Journal of Cardiac Failure. 15:700-708
Background Specific myocardial mitochondrial enzymatic dysfunction and apoptotic remodeling occur in pacing-induced heart failure. We sought to define their regional distribution and molecular basis in the failing heart. Methods and Results Enzyme dy
Publikováno v:
Journal of Molecular Medicine. 85:937-951
Defects in ion channels (channelopathies) are increasingly found in a large spectrum of human pathologies including aging. Mutations in genes encoding ion channel proteins, which disrupt channel function, are the most commonly identified cause of cha
Publikováno v:
Circulation Research. 90:649-656
The cardiac myofilament protein troponin I (cTnI) is phosphorylated by protein kinase C (PKC), a family of serine/threonine kinases activated within heart muscle by a variety of agonists. cTnI is also a substrate for cAMP-dependent protein kinase (PK
Autor:
Feng Pan, Kathleen M. Wood, Dmitri Volfson, Byung Hee Han, Nikolay Pozdnyakov, Gregory J. Zipfel, John R. Cirrito, David Caouette, Kelly R. Bales, Tarek A. Samad, Sharon M. O’Neill, Andrew W. Johnson, YeQing Pi
Publikováno v:
Alzheimer's & Dementia. 10
Autor:
Ronald G. Gregg, X.P. Huang, Kevin J. Lee, Jeffery W. Walker, Patricia A. Powers, YeQing Pi, Anne S. Henkel
Publikováno v:
Circulation Research. 84:1-8
Abstract —Troponin I is a subunit of the thin filament–associated troponin-tropomyosin complex involved in calcium regulation of skeletal and cardiac muscle contraction. We deleted the cardiac isoform of troponin I by using gene targeting in muri
Autor:
YeQing Pi, Jeffery W. Walker
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H1473-H1481
Diacylglycerol has been hypothesized to mediate the positive inotropic response of myocardium to the α-adrenergic agonists angiotensin II and endothelin. The mechanism of action of diacylglycerol was examined here in adult rat ventricular myocytes b