Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ye-juan Zhou"'
Autor:
Wen-jun Wan, Ben-gang You, Xue-nong Zhang, Yu Wang, Meng-tian Chen, Ye-juan Zhou, Yao Tong, Yang Liu, Dan-dan Wang
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:1710-1724
Cancer cells have been reported to exhibit high resistance against immune system recognition through various cell intrinsic and extrinsic mechanisms. Considerable challenges have been encountered in monotherapy with chemotherapeutics to attain the de
Autor:
Wei-liang Chen, Chen-xi Qu, Xue-nong Zhang, Yang Liu, Dan-dan Wang, Meng-tian Chen, Yu Wang, Ye-juan Zhou, Fang Li, Ben-gang You, Shu-di Yang
Publikováno v:
Theranostics
Targeting tumor angiogenesis pathway via VEGF siRNA (siVEGF) has shown great potential in treating highly malignant and metastatic non-small cell lung cancer (NSCLC). However, anti-angiogenic monotherapy lacked sufficient antitumor efficacy which suf
Autor:
Ye-juan Zhou, Wen-jun Wan, Ben-gang You, Xue-nong Zhang, Chen-xi Qu, Fang Li, Liang Zhang, Meng-tian Chen, Yang Liu, Dan-dan Wang
Publikováno v:
International Journal of Pharmaceutics. 566:731-744
Tumor cells avoid immunosurveillance during the tumorigenesis, metastasis and recurrence periods thanks to the overexpressed immunosuppressive molecules on their surface. For instance, the programmed cell death 1 ligand (PD-L1) binds with the T-cells
Autor:
Gui Huang, Ye-juan Zhou, Yu Wang, Hui Li, Wei-liang Chen, Wen-jun Wan, Yang Liu, Ben-gang You, Xue-nong Zhang, Dan-dan Wang
Publikováno v:
International Journal of Pharmaceutics. 585:119456
How to overcome the cell membrane barriers and achieve release payloads efficiently in the cytoplasm have been major challenges for anticancer drug delivery and therapeutic effects with nanosystems. In this study, bovine serum albumin (BSA) was modif
Autor:
Fang Li, Chen-xi Qu, Shu-di Yang, Wei-liang Chen, Xue-nong Zhang, Yang Liu, Ben-gang You, Ji-zhao Li, Zhi-qiang Yuan, Ye-juan Zhou
Publikováno v:
ACS applied materialsinterfaces. 10(43)
Drug development involves various evaluation processes to ascertain drug effects and rigorous analysis of biological indicators during in vitro preclinical studies. Two-dimensional (2D) cell cultures are commonly used in numerous in vitro studies, wh
Autor:
Ben-gang You, Xue-nong Zhang, Fang Li, Ye-juan Zhou, Ji-zhao Li, Chen-xi Qu, Shu-di Yang, Yang Liu, Wei-liang Chen
Publikováno v:
The AAPS journal. 20(2)
Low accumulation in tumor sites and slow intracellular drug release remain as the obstacles for nanoparticles to achieve effective delivery of chemotherapeutic drugs. In this study, multifunctional micelles were designed to deliver doxorubicin (Dox)
Autor:
Chen-xi Qu, Yang Liu, Ye-juan Zhou, Wei-liang Chen, Shu-di Yang, Fang Li, Xue-nong Zhang, Zhi-qiang Yuan, Ji-zhao Li, Wen-jing Zhu, Chun Liu, Xiao-feng Zhou, Ben-gang You
Publikováno v:
ACS applied materialsinterfaces. 8(47)
The efficient delivery of antitumor agents to tumor sites faces numerous obstacles, such as poor cellular uptake and slow intracellular drug release. In this regard, smart nanoparticles (NPs) that respond to the unique microenvironment of tumor tissu