Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ye Jin Chai"'
Autor:
Adekunle T. Bademosi, Elsa Lauwers, Pranesh Padmanabhan, Lorenzo Odierna, Ye Jin Chai, Andreas Papadopulos, Geoffrey J. Goodhill, Patrik Verstreken, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Syntaxin1A (Sx1A) is organized in nanoclusters in neurosecretory cells but how these nanoclusters are affected by neurotransmitter release in a living organism is unknown. Here the authors perform single molecule imaging analysis in live fly larvae a
Externí odkaz:
https://doaj.org/article/c1f4a0305349438cae230c68db71b70f
Autor:
Jocelyn Widagdo, Ye Jin Chai, Margreet C. Ridder, Yu Qian Chau, Richard C. Johnson, Pankaj Sah, Richard L. Huganir, Victor Anggono
Publikováno v:
Cell Reports, Vol 10, Iss 5, Pp 783-795 (2015)
AMPA receptors (AMPARs) have recently been shown to undergo post-translational ubiquitination in mammalian neurons. However, the underlying molecular mechanisms are poorly understood and remain controversial. Here, we report that all four AMPAR subun
Externí odkaz:
https://doaj.org/article/58f93ae5adae47d188584b28a26bb7eb
Autor:
Adekunle T. Bademosi, Elsa Lauwers, Pranesh Padmanabhan, Lorenzo Odierna, Ye Jin Chai, Andreas Papadopulos, Geoffrey J. Goodhill, Patrik Verstreken, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 7: Article number: 13660 (2016); Published: 16 December 2016; Updated: 10 April 2018 The original HTML version of this Article had an incorrect volume number of 8; it should have been 7. This has now been corrected in the HTML;
Externí odkaz:
https://doaj.org/article/4882d431a98f4bb28b6f67561a34cb51
Autor:
Adekunle T. Bademosi, Elsa Lauwers, Pranesh Padmanabhan, Lorenzo Odierna, Ye Jin Chai, Andreas Papadopulos, Geoffrey J. Goodhill, Patrik Verstreken, Bruno van Swinderen, Frédéric A Meunier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number: 13660 (2016); Published: 16 December 2016; Updated: 9 February 2017 This Article was originally published with an incorrect publication date. The paper was due to be published on 3 Jan 2017, but due to an erro
Externí odkaz:
https://doaj.org/article/e0a23471e1714e08a79e6ba4c013b750
Autor:
Vanessa Lanoue, Sarah Weckhuysen, Brett M. Collins, Frederic A. Meunier, Ye Jin Chai, Elizabeth E. Palmer, Julie Z. Brouillet
Publikováno v:
Neurology
De novo pathogenic variants in STXBP1 encoding syntaxin1-binding protein (STXBP1, also known as Munc18-1) lead to a range of early-onset neurocognitive conditions, most commonly early infantile epileptic encephalopathy type 4 (EIEE4, also called STXB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d237dfbbb5cb7b31dc9ffc2da15cc046
https://doi.org/10.1212/wnl.0000000000007786
https://doi.org/10.1212/wnl.0000000000007786
Autor:
Saroja Weeratunga, Mercè Salla-Martret, Ravikiran Kasula, Brett M. Collins, Tristan P. Wallis, Pranesh Padmanabhan, Merja Joensuu, Mahdie Mollazade, Ailisa Blum, Frederic A. Meunier, Emma Livingstone, Julie Z. Brouillet, Jiang Anmin, Rachel S. Gormal, Ramón Martínez-Mármol, Ye Jin Chai
Publikováno v:
SSRN Electronic Journal.
SNARE-mediated secretory vesicle (SV) exocytosis underpins neuronal communication. Munc18-1 orchestrates SNARE complex formation by controlling the opening of syntaxin-1A. How the SV-plasma membrane interface becomes fusion competent at nanoscale lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c541658d4fca4d5690bc9fb323a473e0
https://doi.org/10.2139/ssrn.3362260
https://doi.org/10.2139/ssrn.3362260
Autor:
Rachel S. Gormal, Andreas Papadopulos, Brett M. Collins, Callista B. Harper, Frederic A. Meunier, Daniel Choquet, Isabel C. Morrow, Eric Hosy, Ye Jin Chai, Ravikiran Kasula, Adekunle T. Bademosi
Publikováno v:
The Journal of Cell Biology
Kasula et al. use single-molecule imaging to reveal the diffusional signature for the SNARE proteins Munc18-1 and syntaxin-1A during secretory vesicle priming. The authors show that a conformational change in the Munc18-1 domain 3a hinge-loop regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f951968da6af0368801a64c370c5aea1
https://doi.org/10.1083/jcb.201508118
https://doi.org/10.1083/jcb.201508118
Autor:
Nichole Giles, Rachel S. Gormal, Frederic A. Meunier, Jürgen Götz, Isabel C. Morrow, Ye Jin Chai, Di Xia, Robert G. Parton, Brett M. Collins, Emma Sierecki, Vanesa M. Tomatis, Yann Gambin
Publikováno v:
The Journal of Cell Biology
Munc18-1 heterozygous mutations are associated with developmental diseases, including early infantile epileptic encephalopathy (EIEE). Chai et al. report that Munc18-1 acts as a chaperone for α-synuclein and controls its aggregative propensity. Munc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00479ea7e1c63bc3d6b60b39fe24f659
http://europepmc.org/articles/PMC5021092
http://europepmc.org/articles/PMC5021092
Publikováno v:
FEBS Letters. 587:452-459
α-Synuclein (α-syn) can be secreted from neurons into the extracellular space, affecting the homeostasis of neighboring cells, but the pathophysiology of secreted α-syn remains largely unknown. We found that when exogenously applied to COS-7 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c5b17d20a254a7dd8f48120f42ea21
https://doi.org/10.1016/j.febslet.2013.01.008
https://doi.org/10.1016/j.febslet.2013.01.008