Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Ye Htun"'
Autor:
Samikshya Santosh Nirmala, Kayani Kayani, Mateusz Gliwiński, Yueyuan Hu, Dorota Iwaszkiewicz-Grześ, Magdalena Piotrowska-Mieczkowska, Justyna Sakowska, Martyna Tomaszewicz, José Manuel Marín Morales, Kavitha Lakshmi, Natalia Maria Marek-Trzonkowska, Piotr Trzonkowski, Ye Htun Oo, Anke Fuchs
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The initial idea of a distinct group of T-cells responsible for suppressing immune responses was first postulated half a century ago. However, it is only in the last three decades that we have identified what we now term regulatory T-cells (Tregs), a
Externí odkaz:
https://doaj.org/article/ad7a91b69f724da59a68e02fb2a5ce33
Autor:
Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1252-1264 (2021)
Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined. We aimed to explore the clinical and biochemical course of AIH
Externí odkaz:
https://doaj.org/article/f08765a8d480426d83d9baa2dbcebdaa
Autor:
Nwe Ni Than, James Hodson, Daniel Schmidt-Martin, Richard Taubert, Rebecca E. Wawman, Meemee Botter, Nishant Gautam, Kilian Bock, Rebecca Jones, Gautham D Appanna, Andrew Godkin, Aldo J. Montano-Loza, Frank Lammert, Christoph Schramm, Michael P. Manns, Mark Swain, Kelly W. Burak, David H. Adams, Gideon M Hirschfield, Ye Htun Oo
Publikováno v:
JHEP Reports, Vol 1, Iss 6, Pp 437-445 (2019)
Background & Aims: Treatment options remain limited for patients with autoimmune hepatitis (AIH), while there are still concerns over the consequences of long-term corticosteroid use. A few studies have suggested a role for B cell-driven autoimmune l
Externí odkaz:
https://doaj.org/article/bcb9f7c48c3a4df4a706283363e04ef1
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The tight relationship between the gut and liver on embryological, anatomical and physiological levels inspired the concept of a gut-liver axis as a central element in the pathogenesis of gut-liver axis diseases. This axis refers to the reciprocal re
Externí odkaz:
https://doaj.org/article/308e869485444b0e8d7cee92d71589d3
Autor:
Ye Htun Oo, Susan Ackrill, Richard Cole, Lee Jenkins, Philip Anderson, Hannah C. Jeffery, Nicholas Jones, Louisa E. Jeffery, Philipp Lutz, Rebecca E. Wawman, Amrita Kaur Athwal, Jacqui Thompson, Joanna Gray, Kathy Guo, Darren Barton, Gideon M Hirschfield, Timothy Wong, Peter Guest, David H. Adams
Publikováno v:
JHEP Reports, Vol 1, Iss 4, Pp 286-296 (2019)
Background & Aims: Autoimmune hepatitis (AIH) is an immune-mediated disease with no curative treatment. Regulatory T cell (Treg) therapy is potentially curative in AIH given the critical role of Tregs in preventing autoimmunity. To work effectively,
Externí odkaz:
https://doaj.org/article/af638d03a9eb48ab9834adc56583e9a6
Autor:
Joseph A. Attard, Daniel-Clement Osei-Bordom, Yuri Boteon, Lorraine Wallace, Vincenzo Ronca, Gary Reynolds, M. T. P. R. Perera, Ye Htun Oo, Hynek Mergental, Darius F. Mirza, Simon C. Afford
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Background:Ex situ donor liver machine perfusion is a promising tool to assess organ viability prior to transplantation and platform to investigate novel therapeutic interventions. However, the wide variability in donor and graft characteristics betw
Externí odkaz:
https://doaj.org/article/df6df691064b4286ae0a85871c06d78c
Autor:
Lauren V. Terry, Ye Htun Oo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Regulatory T cells (Tregs) are crucial in maintaining tolerance. Hence, Treg immunotherapy is an attractive therapeutic option in autoimmune diseases and organ transplantations. Currently, autoimmune diseases do not have a curative treatment and tran
Externí odkaz:
https://doaj.org/article/93d58c5f28a240d39406c5f066e368f2
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 2, Pp n/a-n/a (2020)
Abstract The induction of graft tolerance remains the holy grail of transplantation. This is important as chronic allograft dysfunction and the side effects of immunosuppression regimens place a major burden on the lives of transplant patients and th
Externí odkaz:
https://doaj.org/article/d7d91392e0904a768815a94d783fd06f
Autor:
Bonnie van Wilgenburg, Iris Scherwitzl, Edward C. Hutchinson, Tianqi Leng, Ayako Kurioka, Corinna Kulicke, Catherine de Lara, Suzanne Cole, Sirijitt Vasanawathana, Wannee Limpitikul, Prida Malasit, Duncan Young, Laura Denney, STOP-HCV consortium, Michael D. Moore, Paolo Fabris, Maria Teresa Giordani, Ye Htun Oo, Stephen M. Laidlaw, Lynn B. Dustin, Ling-Pei Ho, Fiona M. Thompson, Narayan Ramamurthy, Juthathip Mongkolsapaya, Christian B. Willberg, Gavin R. Screaton, Paul Klenerman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Mucosal Associated Invariant T cells have been implicated in response to bacterial pathogens. Here the authors show that in human viral infections, these cells are activated by IL-18 in cooperation with other pro-inflammatory cytokines, producing int
Externí odkaz:
https://doaj.org/article/cc3459afe5a047aa8c5feb665511a1eb
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/0fcfd14851e14453ba37d33a1adb1764