Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ye H Oo"'
Autor:
Konstantin Knoblich, Sara Cruz Migoni, Susan M Siew, Elizabeth Jinks, Baksho Kaul, Hannah C Jeffery, Alfie T Baker, Muath Suliman, Katerina Vrzalikova, Hisham Mehenna, Paul G Murray, Francesca Barone, Ye H Oo, Philip N Newsome, Gideon Hirschfield, Deirdre Kelly, Steven P Lee, Biju Parekkadan, Shannon J Turley, Anne L Fletcher
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005046 (2018)
The microenvironment of lymphoid organs can aid healthy immune function through provision of both structural and molecular support. In mice, fibroblastic reticular cells (FRCs) create an essential T-cell support structure within lymph nodes, while hu
Externí odkaz:
https://doaj.org/article/cfdd586171da4f0abe7ee7e056ab364c
Autor:
Scott P. Davies, Vincenzo Ronca, Grace E. Wootton, Natalia M. Krajewska, Amber G. Bozward, Rémi Fiancette, Daniel A. Patten, Katharina Yankouskaya, Gary M. Reynolds, Sofia Pat, Daniel C. Osei-Bordom, Naomi Richardson, Liam M. Grover, Christopher J. Weston, Ye H. Oo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The presence of CD8+ T cells in the cytoplasm of biliary epithelial cells (BEC) has been correlated with biliary damage associated with primary biliary cholangitis (PBC). Here, we characterise the mechanism of CD8+ T cell invasion into BEC.
Externí odkaz:
https://doaj.org/article/8c5d5d80fa404d79a9d64d2f03722925
Autor:
James I. Kennedy, Scott P. Davies, Peter W. Hewett, Alex L. Wilkinson, Ye H. Oo, Wei-Yu Lu, Alicia J. El Haj, Shishir Shetty
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Immunotherapy has changed the landscape of treatment options for patients with hepatocellular cancer. Checkpoint inhibitors are now standard of care for patients with advanced tumours, yet the majority remain resistant to this therapy and urgent appr
Externí odkaz:
https://doaj.org/article/a2ab91cef8bf48c791a2da90a324bdec
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The maternal immune system engages in a fine balancing act during pregnancy by simultaneously maintaining immune tolerance to the fetus and immune responses to protect against invading organisms. Pregnancy is an intricately orchestrated process where
Externí odkaz:
https://doaj.org/article/8ae54668141840a9b3b97103d0306495
Autor:
Johannes Hartl, Rosa Miquel, Kalliopi Zachou, Guan-Wee Wong, Asma Asghar, Simon Pape, Marcial Sebode, Moritz Peiseler, Roman Zenouzi, Hanno Ehlken, Till Krech, Christina Weiler-Normann, Joost P.H. Drenth, Ye H. Oo, George Nikolaos Dalekos, Michael Heneghan, Christoph Schramm, Ansgar Wilhelm Lohse
Publikováno v:
JHEP Reports, Vol 2, Iss 3, Pp - (2020)
Background & Aims: High IgG levels are considered a hallmark of autoimmune hepatitis (AIH). A subgroup of patients with AIH has IgG within the normal range despite evidence of clinical disease activity. The clinical significance of this biomarker has
Externí odkaz:
https://doaj.org/article/bcca109810554658a87eabfcfdf0b496
Publikováno v:
Seminars in Immunopathology. 44:393-395
Autor:
Nabil Quraishi, Christopher Quince, Catherine Hewitt, Andrew Beggs, Konstantinos Gerasimidis, Naveen Sharma, Ye H Oo, Peter Hawkey, Natalie J Ives, Susan Manzoor, Nicholas Loman, Richard Hansen, Ailsa Hart, Daniel Gaya, Tariq H Iqbal
Publikováno v:
Oral presentations.
Autor:
Angus, Hann, Anisa, Nutu, George, Clarke, Ishaan, Patel, Dimitri, Sneiders, Ye H, Oo, Hermien, Hartog, M Thamara P R, Perera
Publikováno v:
Transplant International. 35
The effectiveness of liver transplantation to cure numerous diseases, alleviate suffering, and improve patient survival has led to an ever increasing demand. Improvements in preoperative management, surgical technique, and postoperative care have all
Publikováno v:
International journal of molecular sciences. 23(11)
Immune-mediated cholangiopathies are characterised by the destruction of small and large bile ducts causing bile acid stasis, which leads to subsequent inflammation, fibrosis, and eventual cirrhosis of the liver tissue. A breakdown of peripheral hepa
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2016 (2016)
Autoimmune hepatitis (AIH) is an immune mediated liver injury. The precise aetiology of AIH is still unknown but current evidence suggests both genetic and environmental factors are involved. Breakdown in peripheral self-tolerance, and impaired funct
Externí odkaz:
https://doaj.org/article/fb5d973ec9374fe89a2c9bcb3724bc84