Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ye F. Tian"'
Autor:
Lukas W Pfannenstiel, Brian R Gastman, Jennifer S Ko, Marc S Ernstoff, Pauline Funchain, Yee Peng Phoon, Jared E Lopes, Heather C Losey, Claudia Marcela Diaz-Montero, Ye F Tian, Raymond Winquist, Jan Joseph Melenhorst
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Despite recent advances in immunotherapy, a substantial population of late-stage melanoma patients still fail to achieve sustained clinical benefit. Lack of translational preclinical models continues to be a major challenge in the field of
Externí odkaz:
https://doaj.org/article/be91f26ce0d14a72a9d770e7782a5e38
Figure S3 from Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer
Autor:
Brian R. Gastman, Jennifer S. Ko, Joseph Scharpf, Ye F. Tian, C. Marcela Diaz-Montero, Lukas W. Pfannenstiel
Supplementary Figure 3 . CD3+ CD8+ PD-1+ Tim-3+ and CD3+ CD8+ CD27- CD28- cells were sorted from SCCHN tissue. Purified cells were then used in an in vitro suppression assays with autologous T cells. Ratios indicate the number of suppressors to respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1203a076906d39aa2646455d9e6dfeec
https://doi.org/10.1158/2326-6066.22539560.v1
https://doi.org/10.1158/2326-6066.22539560.v1
Autor:
Brian R. Gastman, Jennifer S. Ko, Joseph Scharpf, Ye F. Tian, C. Marcela Diaz-Montero, Lukas W. Pfannenstiel
Immune-checkpoint blockade enhances antitumor responses against cancers. One cancer type that is sensitive to checkpoint blockade is squamous cell carcinoma of the head and neck (SCCHN), which we use here to study limitations of this treatment modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784a7185df9c0921bcc5049c9606d69d
https://doi.org/10.1158/2326-6066.c.6549122.v1
https://doi.org/10.1158/2326-6066.c.6549122.v1
Autor:
Yee Peng Phoon, Jared E. Lopes, Lukas W. Pfannenstiel, C. Marcela Diaz-Montero, Ye F. Tian, Marc S. Ernstoff, Pauline Funchain, XiaoXia Li, Heather C. Losey, Raymond J. Winquist, Brian R. Gastman
Publikováno v:
Cancer Research. 83:1818-1818
Introduction: The development and FDA approval of drugs targeting the PD-1/PD-L1 axis has greatly shifted the paradigm of immunotherapy and has improved the clinical outcome for patients diagnosed with advanced melanoma. Despite the recent advancemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69baa6a476e073733a257791a114a416
https://doi.org/10.1158/1538-7445.am2023-1818
https://doi.org/10.1158/1538-7445.am2023-1818
Autor:
C. Marcela Diaz-Montero, Ye F. Tian, Joseph Scharpf, Brian R. Gastman, Lukas W. Pfannenstiel, Jennifer S. Ko
Publikováno v:
Cancer Immunology Research
Immune-checkpoint blockade enhances antitumor responses against cancers. One cancer type that is sensitive to checkpoint blockade is squamous cell carcinoma of the head and neck (SCCHN), which we use here to study limitations of this treatment modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d84df7d70dc1cfe68a02568d05bb55
Autor:
Ye F Tian, Anthony T. Vella, Beiyan Zhou, Antoine Ménoret, Brian R. Gastman, C. Marcela Diaz-Montero, Annabelle Rodriguez, Michael Cartwright, Samjhana Thapaliya, Chuan Li, Jung-Min Song, Cheryl M. Cameron, Banumathi Tamilselvan, Pauline Funchain, Christopher P. Bonin, Keaton Karlinsey, Mark J. Cameron, Yee Peng Phoon, Alyssa Matz, Jackelyn B. Golden, Lili Qu, Angkana Thongkum
Publikováno v:
The Journal of experimental medicine. 219(1)
Immune checkpoint inhibitor (ICI) therapy continues to revolutionize melanoma treatment, but only a subset of patients respond. Major efforts are underway to develop minimally invasive predictive assays of ICI response. Using single-cell transcriptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f144ed948cb822a7565490e6589409e
https://pubmed.ncbi.nlm.nih.gov/34807232
https://pubmed.ncbi.nlm.nih.gov/34807232
Autor:
Leandro Cerchietti, Ankur Singh, David M. Bassen, Jonathan T. Butcher, Ye F. Tian, Fnu Apoorva, Timothy M. Pierpont, Robert S. Weiss
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:1833-1844
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma, with multiple molecular subtypes. The activated B-cell-like DLBCL subtype accounts for roughly one-third of all the cases and has an inferior prognosis. There is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be63ba7564ae36e7f7f526c9e8e1b8f7
https://doi.org/10.1002/jbm.a.36031
https://doi.org/10.1002/jbm.a.36031
Publikováno v:
Annals of Biomedical Engineering. 44:2062-2075
Osteoarthritis (OA) is a progressive, degenerative disease of articulating joints that not only affects the elderly, but also involves younger, more active individuals with prolonged participation in high physical-demand activities. Thus, effective t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356c260c8dde99d3f3adb42b5c10fa72
https://doi.org/10.1007/s10439-016-1600-z
https://doi.org/10.1007/s10439-016-1600-z
Autor:
Lukas W, Pfannenstiel, C Marcela, Diaz-Montero, Ye F, Tian, Joseph, Scharpf, Jennifer S, Ko, Brian R, Gastman
Publikováno v:
Cancer immunology research. 7(3)
Immune-checkpoint blockade enhances antitumor responses against cancers. One cancer type that is sensitive to checkpoint blockade is squamous cell carcinoma of the head and neck (SCCHN), which we use here to study limitations of this treatment modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f50da8eabba3473f007ffbdf830154f
https://pubmed.ncbi.nlm.nih.gov/30728151
https://pubmed.ncbi.nlm.nih.gov/30728151
Publikováno v:
Cellular and Molecular Bioengineering. 8:471-487
Galectins are carbohydrate-binding proteins that act as extracellular signaling molecules in various normal and pathological processes. Galectin bioactivity is mediated by specific non-covalent interactions with cell-surface and extracellular matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dcd039b0b9f4486e330695fdef339e
https://doi.org/10.1007/s12195-015-0399-2
https://doi.org/10.1007/s12195-015-0399-2