Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Ye Chen‐Izu"'
Autor:
Huijia Wang, Guangxian Zhu, Leighton T. Izu, Ye Chen-Izu, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Given the direct association with malignant ventricular arrhythmias, cardiotoxicity is a major concern in drug design. In the past decades, computational models based on the quantitative structure–activity relationship have been propo
Externí odkaz:
https://doaj.org/article/aaf79c6863b04ba7aa4e1681727936ec
Autor:
Sota Kudo, Zheng Chen, Xue Zhou, Leighton T. Izu, Ye Chen-Izu, Xin Zhu, Toshiyo Tamura, Shigehiko Kanaya, Ming Huang
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Photoplethysmography (PPG) signal is potentially suitable in atrial fibrillation (AF) detection for its convenience in use and similarity in physiological origin to electrocardiogram (ECG). There are a few preceding studies that have shown the possib
Externí odkaz:
https://doaj.org/article/9d7df1295d714287868c3d2c5150e593
Autor:
Mohammad A. Kazemi-Lari, Rafael Shimkunas, Zhong Jian, Bence Hegyi, Leighton Izu, John A. Shaw, Alan S. Wineman, Ye Chen-Izu
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104810- (2022)
Externí odkaz:
https://doaj.org/article/f84c1ae7680e4f5289252a4ab7ed1f2f
Autor:
Balázs Horváth, Norbert Szentandrássy, Csaba Dienes, Zsigmond M. Kovács, Péter P. Nánási, Ye Chen-Izu, Leighton T. Izu, Tamas Banyasz
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The patch clamp technique underwent continual advancement and developed numerous variants in cardiac electrophysiology since its introduction in the late 1970s. In the beginning, the capability of the technique was limited to recording one single cur
Externí odkaz:
https://doaj.org/article/5a6d3cd79aa44352a76be3308cc0e474
Autor:
Yankun Lyu, Phung N. Thai, Lu Ren, Valeriy Timofeyev, Zhong Jian, Seojin Park, Kenneth S. Ginsburg, James Overton, Julie Bossuyt, Donald M. Bers, Ebenezer N. Yamoah, Ye Chen-Izu, Nipavan Chiamvimonvat, Xiao-Dong Zhang
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103624- (2022)
Summary: The mammalian heart beats incessantly with rhythmic mechanical activities generating acids that need to be buffered to maintain a stable intracellular pH (pHi) for normal cardiac function. Even though spatial pHi non-uniformity in cardiomyoc
Externí odkaz:
https://doaj.org/article/71ec355c18ca46c0abb871b3e9983834
Autor:
Leighton Izu, Rafael Shimkunas, Zhong Jian, Bence Hegyi, Mohammad Kazemi-Lari, Anthony Baker, John Shaw, Tamas Banyasz, Ye Chen-Izu
Publikováno v:
Life, Vol 11, Iss 6, p 503 (2021)
The heart has two intrinsic mechanisms to enhance contractile strength that compensate for increased mechanical load to help maintain cardiac output. When vascular resistance increases the ventricular chamber initially expands causing an immediate le
Externí odkaz:
https://doaj.org/article/4a4932e33c8b4ed4a4373a5000d05317
Autor:
Zhong Jian, Yi-Je Chen, Rafael Shimkunas, Yuwen Jian, Mark Jaradeh, Karen Chavez, Nipavan Chiamvimonvat, Jil C Tardiff, Leighton T Izu, Robert S Ross, Ye Chen-Izu
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160605 (2016)
Isolation of high quality cardiomyocytes is critically important for achieving successful experiments in many cellular and molecular cardiology studies. Methods for isolating cardiomyocytes from the murine heart generally are time-sensitive and exper
Externí odkaz:
https://doaj.org/article/2310d847ebcf4ff785924dcfc7a34c51
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143475 (2015)
Variability is inherent in any population, regardless whether the population comprises humans, plants, biological cells, or manufactured parts. Is the variability beneficial, detrimental, or inconsequential? This question is of fundamental importance
Externí odkaz:
https://doaj.org/article/dd565587ee9d4762b6d25f8a600e3fe9
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75492 (2013)
Cardiac myocytes experience mechanical stress during each heartbeat. Excessive mechanical stresses under pathological conditions cause functional and structural remodeling that lead to heart diseases, yet the precise mechanisms are still incompletely
Externí odkaz:
https://doaj.org/article/595b6e0dfbd24509ab4ce37f3bee910f
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2.
Autor:
Woltz, Ryan L., Yang Zheng, Choi, Woori, Ngo, Khoa, Trinh, Pauline, Lu Ren, Thai, Phung N., Harris, Brandon J., Yanxiao Han, Rouen, Kyle C., Lopez Mateos, Diego, Zhong Jian, Ye Chen-Izu, Dickson, Eamonn J., Yamoah, Ebenezer N., Yarov-Yarovoy, Vladimir, Vorobyov, Igor, Xiao-Dong Zhang, Chiamvimonvat, Nipavan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/24/2024, Vol. 121 Issue 39, p1-12, 39p