Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Ye‐Guang Chen"'
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-11 (2024)
Abstract The intestine, is responsible for food digestion, nutrient absorption, endocrine secretion, food residue excretion, and immune defense. These function performances are based on the intricate composition of intestinal epithelial cells, encomp
Externí odkaz:
https://doaj.org/article/1ea9ccbfdcd6409a8c80eb33bbe02170
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Intestinal epithelial cells (IECs) are pivotal for maintaining intestinal homeostasis through self-renewal, proliferation, differentiation, and regulated cell death. While apoptosis and necroptosis are recognized as distinct pathways, their
Externí odkaz:
https://doaj.org/article/e63cbb41294e4a50bfd44d742a16ece9
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-5 (2024)
Abstract The family of secreted dimeric proteins known as the Transforming Growth Factor-β (TGF-β) family plays a critical role in facilitating intercellular communication within multicellular animals. A recent symposium on TGF-β Biology - Signali
Externí odkaz:
https://doaj.org/article/d0acd9558a5344b99d2a85d3e1ba8b9c
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-4 (2024)
Abstract Human cardiac and other organoids have recently emerged as a groundbreaking tool for advancing our understanding the developmental biology of human organs. A recent paper from Sasha Mendjan’s laboratory published in the journal Cell on Dec
Externí odkaz:
https://doaj.org/article/e41cd61f35f54e12832207334476f3b7
Autor:
PLOS Biology Editors, Mengmeng Niu, Yajun He, Jing Xu, Liangping Ding, Tao He, Yong Yi, Mengyuan Fu, Rongtian Guo, Fengtian Li, Hu Chen, Ye-Guang Chen, Zhi-Xiong Jim Xiao
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002708 (2024)
Externí odkaz:
https://doaj.org/article/6298b42c7c344739817ff8bd44582fd9
The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling
Autor:
Siting Wei, Meng Li, Wanlu Song, Jiaye Liu, Shicheng Yu, Yalong Wang, Mengxian Zhang, Huijun Du, Yuan Liu, Huidong Liu, Wei Fu, Baojie Li, Ye-Guang Chen
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Paracrine signals play pivotal roles in organ homeostasis. Mesenchymal stromal cells (MSCs) play a key role in regulating epithelium homeostasis in the intestine while their paracrine effects are poorly characterized. Here, we identified pro
Externí odkaz:
https://doaj.org/article/4db0f0b95d134484b83983e6189506ce
A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche
Autor:
Jinnan Xiang, Jigang Guo, Shaoyang Zhang, Hongguang Wu, Ye-Guang Chen, Junping Wang, Baojie Li, Huijuan Liu
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background The nutrient-absorbing villi of small intestines are renewed and repaired by intestinal stem cells (ISCs), which reside in a well-organized crypt structure. Genetic studies have shown that Wnt molecules secreted by telocytes, Gli1
Externí odkaz:
https://doaj.org/article/f6f8689f796447e3bb47d4a24365f0aa
Autor:
Xiaodan Wang, Fan Hong, Haonan Li, Yalong Wang, Mengxian Zhang, Shibo Lin, Hui Liang, Hongwen Zhou, Yuan Liu, Ye-Guang Chen
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-14 (2023)
Abstract As an important part of the stomach, gastric antrum secretes gastrin which can regulate acid secretion and gastric emptying. Although most cell types in the gastric antrum are identified, the comparison of cell composition and gene expressio
Externí odkaz:
https://doaj.org/article/d878b831582b4d47baa438de8f800721
Autor:
Hanqing Lin, Yalong Wang, Chunyan Cheng, Yuxin Qian, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu-Xia Deng, Bing Zhao, Jiani Cao, Lei Wang, Liu Wang, Lingmin Liang, Wenli Kelly Chen, Chunping Yu, Zhijian Sun, Yingying Yang, Changlin Wang, Yong Zhang, Qiyuan Li, Ka Li, Aijin Ma, Tongbiao Zhao, Ye-Guang Chen, Guoqiang Hua
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract Intestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade. Human intestinal cancer organoids are physiologically relevant in vitro models, which provid
Externí odkaz:
https://doaj.org/article/26a5684557e44f23b9d27f6534aa642f
Autor:
Yalong Wang, Hanqing Lin, Lianzheng Zhao, Fan Hong, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu-Xia Deng, Bing Zhao, Jiani Cao, Lei Wang, Liu Wang, Lingmin Liang, Wenli Kelly Chen, Chunping Yu, Zhijian Sun, Yingying Yang, Changlin Wang, Yong Zhang, Qiyuan Li, Ka Li, Aijin Ma, Tongbiao Zhao, Guoqiang Hua, Ye-Guang Chen
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-5 (2023)
Abstract Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prominent obstacle to limit their tr
Externí odkaz:
https://doaj.org/article/99a3ab1fa2af47958a73f133d678bdec