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CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages.

Autor: Wang JB; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Gao YX; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Ye YH; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Lin TX; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Li P; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Lin JX; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Chen QY; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Cao LL; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Lin M; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Tu RH; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Lin JL; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Huang ZN; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Zheng HL; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Xie JW; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China., Zheng CH; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China. wwkzch@163.com.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China. wwkzch@163.com.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China. wwkzch@163.com., Huang CM; Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China. hcmlr2002@fjmu.edu.cn.; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China. hcmlr2002@fjmu.edu.cn.; Fujian Key Laboratory of Tumour Microbiology, Fujian Medical University, Fuzhou, China. hcmlr2002@fjmu.edu.cn.

Publikováno v: Cancer gene therapy [Cancer Gene Ther] 2023 Jan; Vol. 30 (1), pp. 22-37. Date of Electronic Publication: 2022 Aug 23.