Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia.

Autor: Gordon, Hannah^1,2 (AUTHOR), Schafer, Zachary T.¹ (AUTHOR), Smith, Cody J.^1,2 (AUTHOR) csmith67@nd.edu

Publikováno v: PLoS Biology. 10/30/2024, Vol. 22 Issue 10, p1-20. 20p.

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury.

Autor: Ydens E; Peripheral Neuropathy Research Group, Department of Biomedical Sciences, Institute Born Bunge, University of Antwerp, Antwerp, Belgium.; VIB Center for Inflammation Research, Ghent, Belgium., Amann L; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Asselbergh B; VIB-UAntwerp Center for Molecular Neurology, University of Antwerp, Antwerp, Belgium., Scott CL; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Martens L; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Sciences and Statistics, Ghent University, Ghent, Belgium., Sichien D; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Mossad O; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Blank T; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., De Prijck S; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Low D; Singapore Immunology Network, Agency for Science Technology and Research, Singapore, Singapore., Masuda T; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Saeys Y; VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Sciences and Statistics, Ghent University, Ghent, Belgium., Timmerman V; Peripheral Neuropathy Research Group, Department of Biomedical Sciences, Institute Born Bunge, University of Antwerp, Antwerp, Belgium., Stumm R; Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany., Ginhoux F; Singapore Immunology Network, Agency for Science Technology and Research, Singapore, Singapore., Prinz M; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany. marco.prinz@uniklinik-freiburg.de.; Signalling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany. marco.prinz@uniklinik-freiburg.de.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany. marco.prinz@uniklinik-freiburg.de., Janssens S; VIB Center for Inflammation Research, Ghent, Belgium. sophie.janssens@irc.vib-ugent.be.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium. sophie.janssens@irc.vib-ugent.be., Guilliams M; VIB Center for Inflammation Research, Ghent, Belgium. martin.guilliams@irc.ugent.be.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. martin.guilliams@irc.ugent.be.

Publikováno v: Nature neuroscience [Nat Neurosci] 2020 May; Vol. 23 (5), pp. 676-689. Date of Electronic Publication: 2020 Apr 13.

Neither injury induced macrophages within the nerve, nor the environment created by Wallerian degeneration is necessary for enhanced in vivo axon regeneration after peripheral nerve injury.

Autor: Talsma, Aaron D.¹ (AUTHOR), Niemi, Jon P.¹ (AUTHOR), Zigmond, Richard E.¹ (AUTHOR) rez@case.edu

Publikováno v: Journal of Neuroinflammation. 5/27/2024, Vol. 21 Issue 1, p1-25. 25p.

Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-κb Pathway.

Autor: Ruoyan Xue¹, Mengyao Xie¹, Zhiyuan Wu^1,2, Shu Wang¹, Yongli Zhang¹, Zhijin Han¹, Chen Li¹, Qi Tang¹, Liping Wang³, Di Li³, Shihua Wang³, Hua Yang¹ dr_yanghua2021@163.com, Chunhua Zhao, Robert^3,4 zhaochunhua@ibms.pumc.edu.cn

Publikováno v: Aging & Disease. Apr2024, Vol. 15 Issue 2, p851-868. 18p.

The Next Generation of Biomarker Research in Spinal Cord Injury.

Autor: Ydens E; Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Hasselt University, Martelarenlaan 42, 3500, Hasselt, Belgium., Palmers I; Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Hasselt University, Martelarenlaan 42, 3500, Hasselt, Belgium., Hendrix S; Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Hasselt University, Martelarenlaan 42, 3500, Hasselt, Belgium., Somers V; Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Diepenbeek, Hasselt University, Martelarenlaan 42, 3500, Hasselt, Belgium. veerle.somers@uhasselt.be.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2017 Mar; Vol. 54 (2), pp. 1482-1499. Date of Electronic Publication: 2016 Feb 05.