Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yazhen Shang"'
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27161- (2024)
The aim of this study was to investigate the possible molecular mechanism of Scutellaria baicalensis Georgi stems and leaves flavonoids (SSF) in Alzheimer's disease (AD). The active ingredients of SSF and their targets were identified via network pha
Externí odkaz:
https://doaj.org/article/34e25cb77a0847b8a77021c36084ed5c
Publikováno v:
Journal of Biosciences and Medicines. 11:82-97
Autor:
Shengkai Ding, Yazhen Shang
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 21:367-374
Background: Neurofibrillary Tangles (NFTs), formed by hyperphosphorylation of Tau protein in Alzheimer's Disease (AD), arethe main pathomechanisms of neuronal degeneration, which indicate a sign of brain disorder. NFTs are positively correlated with
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 21:354-366
Background: It is well known that Alzheimer's Disease (AD) is a neurodegenerative disease accompanied by memory impairment and major pathological changes of the extracellular Senile Plaque (SP) and intracellular Neurofibrillary Tangles (NFTs). Howeve
Autor:
Xinyang Liu, Yuling Liu, Jianjun Cheng, Yang Gao, Chunying Zhao, Shuai Ma, Caixia Li, Yazhen Shang
Background The present study was aimed to investigate the effect and molecular mechanism of Scutellaria barbata flavonoids (SBFs) in promoting neurogenesis and improving memory impairment mediated by CREB phosphorylation in rats. Methods Alzheimer’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75253f4d9017bb9e577b243f67e63bd
https://doi.org/10.21203/rs.3.rs-2657404/v1
https://doi.org/10.21203/rs.3.rs-2657404/v1
Background AD is a progressive neurodegenerative disease that seriously threatens the physical and mental health for the elderly. The disease is pathologically associated with Aβ plaque deposition, tau hyperphosphorylation, cholinergic damage, oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e8fa362de3f14d7ce5b3d38ce8cf7f
https://doi.org/10.21203/rs.3.rs-2387373/v1
https://doi.org/10.21203/rs.3.rs-2387373/v1
Publikováno v:
Medicinal Plant; Aug2020, Vol. 11 Issue 4, p1-9, 3p
Publikováno v:
Medicinal Plant; Jun2020, Vol. 11 Issue 3, p15-17, 3p
Publikováno v:
Medicinal Plant; Dec2018, Vol. 9 Issue 6, p76-88, 7p
Publikováno v:
Neural Regeneration Research
Based on previous studies that have shown flavonoids from the stems and leaves of Scutellaria baicalensis Georgi are neuroprotective agents in a naturally senile, D-galactose, aging in vivo model, as well as an in vitro model of oxidative/hypoxic inj