Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yazhen, Hong"'
Autor:
Kunyu Liao, Pengda Chen, Mengdi Zhang, Jiazhen Wang, Teri Hatzihristidis, Xiaoxi Lin, Liang Yang, Nan Yao, Chenfeng Liu, Yazhen Hong, Xia Li, Hong Liu, Juan Carlos Zúñiga-Pflücker, Paul E. Love, Xiang Chen, Wen-Hsien Liu, Bin Zhao, Changchun Xiao
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114261- (2024)
Summary: Thymocyte development requires precise control of PI3K-Akt signaling to promote proliferation and prevent leukemia and autoimmune disorders. Here, we show that ablating individual clusters of the miR-17∼92 family has a negligible effect on
Externí odkaz:
https://doaj.org/article/53ba8c025dbc4c46a8e163800c322562
Autor:
Yan Wang, Quan Zhang, Tingting He, Yechen Wang, Tianqi Lu, Zengge Wang, Yiyi Wang, Shen Lin, Kang Yang, Xinming Wang, Jun Xie, Ying Zhou, Yazhen Hong, Wen-Hsien Liu, Kairui Mao, Shih-Chin Cheng, Xin Chen, Qiyuan Li, Nengming Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Type 1 conventional dendritic cells (cDC1) are the most efficient cross-presenting cells that induce protective cytotoxic T cell response. However, the regulation of their homeostasis and function is incompletely understood. Here we observe
Externí odkaz:
https://doaj.org/article/c7ad487a99994244b069b0dfc088305f
Autor:
Xiaojuan Zhou, Xian Jia, Zhe Huang, Chao Yang, Jiali Li, Wangnan Xie, Xiaoyu He, Wei Ying, Chenfeng Liu, Yun Liu, Kunyu Liao, Yazhen Hong, Xiao Lei Chen, Tianying Zhang, Ningshao Xia, Wen-Hsien Liu, Guo Fu, Changchun Xiao
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113452- (2023)
Summary: Major histocompatibility complex (MHC) class II-reactive CD8+ T cells are found in humans and animals, but little is known about their identity, development, and function. In this study, we discover a group of CD8+ T cells reactive to both M
Externí odkaz:
https://doaj.org/article/a6bdea10b96c49c7ad8baea311a47ddd
Autor:
Jun Xie, Ying Du, Dewang Liu, Jianfeng Wu, Kang Yang, Xiaoyu He, Jiayi Zhao, Peicheng Hong, Kunyu Liao, Huanrong Zhang, Yazhen Hong, John R. Teijaro, Seung Goo Kang, Changchun Xiao, Wen-Hsien Liu
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112968- (2023)
Summary: The miR-17∼92 family microRNAs (miRNAs) play a key role in germinal center (GC) reaction through promoting T follicular helper (TFH) cell differentiation. It remains unclear whether they also have intrinsic functions in B cell differentiat
Externí odkaz:
https://doaj.org/article/4840eac0546146ffbc02268b340bfaf1
Autor:
Lingtao Yang, Wei Chen, Li Li, Yueyue Xiao, Shilin Fan, Quan Zhang, Tian Xia, Mengjie Li, Yazhen Hong, Tongjin Zhao, Qiyuan Li, Wen-Hsien Liu, Nengming Xiao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Follicular helper T (TFH) cells are specialized CD4+ helper T cells that provide help to B cells in humoral immunity. However, the molecular mechanism underlying generation of TFH cells is incompletely understood. Here, we reported that Damage-specif
Externí odkaz:
https://doaj.org/article/4c48cf169b94420cbdcb0bbaae112df5
Autor:
Xiaoyu He, Jiayi Zhao, Abidan Adilijiang, Peicheng Hong, Pengda Chen, Xinyong Lin, Jun Xie, Ying Du, Yun Liu, Lianghua Lin, Hyun Yong Jin, Yazhen Hong, Wen-Hsien Liu, Changchun Xiao
Publikováno v:
Cellular & Molecular Immunology. 20:277-291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc60eefd18ed3eed4798b88502e385d7
https://doi.org/10.1038/s41423-022-00972-0
https://doi.org/10.1038/s41423-022-00972-0
Publikováno v:
Magnetochemistry, Vol 7, Iss 8, p 115 (2021)
The Magnetospirillum magneticum AMB-1 species is one of the most widely used magnetotactic bacterial strains for producing magnetosomes under laboratory conditions. Nevertheless, there exist several challenges in expanding and purifying the AMB-1 cul
Externí odkaz:
https://doaj.org/article/ea5c2da5a669464aafb02ed6b34f101c
Autor:
Chao Yang, Yun Liu, Yudi Hu, Liang Fang, Zhe Huang, Huanhuan Cui, Jun Xie, Yazhen Hong, Wei Chen, Nengming Xiao, Qiyuan Li, Wen-Hsien Liu, Changchun Xiao
Publikováno v:
Cellular & Molecular Immunology. 19:1030-1041
Aberrant expression of Myc is one of the most common oncogenic events in human cancers. Scores of Myc inhibitors are currently under development for treating Myc-driven cancers. In addition to directly targeting tumor cells, Myc inhibition has been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53e0362d8fe9162468abf31746ed27d
https://doi.org/10.1038/s41423-022-00898-7
https://doi.org/10.1038/s41423-022-00898-7
Autor:
Wen-Hsien Liu, Fu Yubing, Jinjia Wang, Chenfeng Liu, Kunyu Liao, Xianjun Gao, Ronghan Tang, Binbin Fan, Yazhen Hong, Nengming Xiao, Changchun Xiao
Cellular immunity mediated by CD8+ T cells plays an indispensable role in clearance of bacteria and virus infection and cancers. However, persistent antigen stimulation of CD8+ T cells leads to an exhausted or dysfunctional state characterized by los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10060650c943e89c9c3b3bc7d6abbaee
https://doi.org/10.21203/rs.3.rs-2678038/v1
https://doi.org/10.21203/rs.3.rs-2678038/v1
Autor:
Qingmei Liu, Yu Zhou, Lei Ma, Fudie Gu, Kunyu Liao, Yan Liu, Yuehua Zhang, Hong Liu, Yazhen Hong, Minjie Cao, Wen-Hsien Liu, Chenfeng Liu, Guangming Liu
Publikováno v:
Carbohydrate polymers. 288
Seaweeds are important "blue food" and some seaweeds have been demonstrated that have the immunoregulation activities and benefit for human health. However, which immune cell subsets are targeted and how immune processes are regulated by those seawee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa40d3c9901216a288d0dd18cb7b77b3
https://pubmed.ncbi.nlm.nih.gov/35450639
https://pubmed.ncbi.nlm.nih.gov/35450639