Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yazen Jmeian"'
Autor:
Daria V. Sizova, Steve Raiker, Deaneira Lakheram, Vishwanatha Rao, Andrew Proffitt, Yazen Jmeian, Walter Voegtli, Melissa Batonick
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101442- (2023)
Amyloid light-chain (AL) amyloidosis is the second most common form of systemic amyloidosis which is characterized by a high level of mortality and no effective treatment to remove fibril deposition. This disorder is caused by malfunctioning of B-cel
Externí odkaz:
https://doaj.org/article/b8510742fe9145c8b59634f92717a2a8
Autor:
Jeanne Magram, Ying Fu, Stephane Angers, Kevin K. Lin, Melissa Beilschmidt, Jean-Philippe Julien, Alejandro Duque, Jason Moffat, Keith Mascall, Francine Lui, Sachdev S. Sidhu, Swetha Raman, Minh D. To, Mark Ng, Yazen Jmeian, Minerva Fernandez, Xiaowei Wang, Guohua Pan, Angus M. Sinclair, Johan E. S. Fransson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6812-6817
Aberrant activation of Wnt/β-catenin signaling occurs frequently in cancer. However, therapeutic targeting of this pathway is complicated by the role of Wnt in stem cell maintenance and tissue homeostasis. Here, we evaluated antibodies blocking 6 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2465a558324ba0db09a6e63c504a3055
https://doi.org/10.1073/pnas.1817246116
https://doi.org/10.1073/pnas.1817246116
Autor:
Yael David, Devin M Ray, Ivo C. Lorenz, Jakob M Hebert, Adewola Osunsade, Yazen Jmeian, Nicholas A Prescott
Publikováno v:
Biochemistry. 58:171-176
Higher order compaction of the eukaryotic genome is key to the regulation of all DNA-templated processes, including transcription. This tightly controlled process involves the formation of mononucleosomes, the fundamental unit of chromatin, packaged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35429ff285ae223896e465ac9042ccd7
https://doi.org/10.1021/acs.biochem.8b01060
https://doi.org/10.1021/acs.biochem.8b01060
Autor:
Shalom Goldberg, Wenying Jian, Wayne C. Widdison, Vadim Dudkin, Luke Harris, Naidong Weng, Karyn O'neil, Yazen Jmeian, Sharon Wilhelm, Darryl Davis, Chuan Shi, Tricia Lin
Publikováno v:
Bioanalysis. 10(20)
Aim: Alternative scaffold proteins have emerged as novel platforms for development of therapeutic applications. One such application is in protein–drug conjugates (PDCs), which are analogous to antibody–drug conjugates. Methodology: Liquid chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fbeb17866b972da16ca5593721a986
https://pubmed.ncbi.nlm.nih.gov/30372128
https://pubmed.ncbi.nlm.nih.gov/30372128
Autor:
Vadim Dudkin, Sharon D. Wilhelm, Wayne C. Widdison, Karyn O'neil, Shalom Goldberg, Wenying Jian, Yazen Jmeian, Luke Harris, Darryl Davis, Tricia Lin, Chuan Shi, Naidong Weng
Publikováno v:
Analytical chemistry. 90(8)
Bioanalysis of antibody-drug conjugates (ADCs) is challenging due to the complex, heterogeneous nature of their structures and their complicated catabolism. To fully describe the pharmacokinetics (PK) of an ADC, several analytes are commonly quantifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796b29f12c6455f1131bce6fe62bd8a0
https://pubmed.ncbi.nlm.nih.gov/29589741
https://pubmed.ncbi.nlm.nih.gov/29589741
Autor:
Zainab Haybe, Mark Ng, Melissa Beilschmidt, Minh D. To, Kevin K. Lin, Jeanne Magram, James Pan, Jean-Philippe Julien, Yazen Jmeian, Sachdev S. Sidhu, Johan E. S. Fransson, Stephane Angers, Jason Moffat, Angus Sinclair, Minerva Fernandez, Swetha Raman, Keith Mascall, Ying Fu, Francine Lui
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:a297-a297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b57353fdf1804a157c54bcf4db9c9a2
https://doi.org/10.1107/s0108767318097039
https://doi.org/10.1107/s0108767318097039
Autor:
Ziad El Rassi, Yazen Jmeian
Publikováno v:
ELECTROPHORESIS. 30:249-261
This review article is concerned with (i) proteomic sample preparation including among other things the depletion of high-abundance proteins and the concentration of low-abundance proteins and (ii) their subsequent prefractionation for further analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5640c140c96b0c181e7087c4e8b36f9a
https://doi.org/10.1002/elps.200800639
https://doi.org/10.1002/elps.200800639
Autor:
Ziad El Rassi, Yazen Jmeian
Publikováno v:
Journal of proteome research. 8(10)
In this report, we describe an integrated fluidic platform composed of tandem affinity columns for the depletion of high-abundance proteins from human serum and on-line fractionation/concentration of medium- and low-abundance proteins by tandem immob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b6db39e36232d44b99564030d46ef0
https://pubmed.ncbi.nlm.nih.gov/19670910
https://pubmed.ncbi.nlm.nih.gov/19670910
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 37(5)
A specific hyphenated high performance liquid chromatography-mass spectrometric (LC-MS/MS) assay was developed for the determination of captopril in plasma. The drug was extracted from plasma using liquid-liquid extraction with a mixture of diethylet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c869c3d20f2073722c3fd3fb4b57c42c
https://pubmed.ncbi.nlm.nih.gov/15862687
https://pubmed.ncbi.nlm.nih.gov/15862687
Autor:
Yazen Jmeian, Ziad El Rassi
Publikováno v:
Journal of Proteome Research; Oct2009, Vol. 8 Issue 10, p4592-4603, 12p