Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yazan M. Al-Hasan"'
Publikováno v:
Case Reports in Neurological Medicine
Case Reports in Neurological Medicine, Vol 2020 (2020)
Case Reports in Neurological Medicine, Vol 2020 (2020)
Susac syndrome (SuS) is a rare poorly characterised disorder that affects the brain, retina, and cochlea. Here, we present a case of a 31-year-old pregnant female with a new diagnosis of SuS that was successfully managed to 36 weeks of gestation with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dfa384acda7fb5d417cef38df132aa
http://europepmc.org/articles/PMC7775175
http://europepmc.org/articles/PMC7775175
Publikováno v:
Expert opinion on investigational drugs. 28(6)
INTRODUCTION: Alzheimer’s dementia (AD) is the most common form of dementia in the World. Pathologically, it is characterized by extracellular β-amyloid plaques and intraneuronal neurofibrillary tangles (NFTs). The latter is composed of irregular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7d7157134c32fa16934c912efaa708
https://pubmed.ncbi.nlm.nih.gov/31094578
https://pubmed.ncbi.nlm.nih.gov/31094578
Autor:
Yazan M. Al-Hasan, Jessica A. Groot, Peter J. Syapin, David R. M. Trotter, Joseph M. Martinez, David C. Curtis, Patrick C. Marquardt, Carol Baby, Clayton L. Allison, Matthew J. Scheible, Susan E. Bergeson, David S. Edwards, Jose Luis Redondo, Katy T. Nicholson, Ismael Segura-Ulate
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:2482-2490
Background New pharmacotherapies to treat alcohol use disorders (AUD) are needed. Given the complex nature of AUD, there likely exist multiple novel drug targets. We, and others, have shown that the tetracycline drugs, minocycline and doxycycline, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8bf7cb14c5efccf0f6459874198a934
https://doi.org/10.1111/acer.13253
https://doi.org/10.1111/acer.13253
A significant portion of the clinical phenotype observed in Alzheimer's disease (AD) occurs through nicotinic acetylcholine receptors (nAChRs). Degeneration of cholinergic neurons, combined with aberrant nAChR expression and activation partially thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5764afa48e2e12b472f2d791e6d51d
https://europepmc.org/articles/PMC6379052/
https://europepmc.org/articles/PMC6379052/
Autor:
Lisa Arnold, Patrick McGeer, Marwan N. Sabbagh, Yazan M. Al-Hasan, Moonhee Lee, Jennifer Heim, Jiong Shi
Publikováno v:
BMC Neurology
BMC Neurology, Vol 18, Iss 1, Pp 1-4 (2018)
BMC Neurology, Vol 18, Iss 1, Pp 1-4 (2018)
Background Peripheral diagnostics for Alzheimer’s disease (AD) continue to be developed. Diagnostics capable of detecting AD before the onset of symptoms are particularly desirable, and, given the fact that early detection is imperative for allevia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d035737cc3d539bebb1fa3ec897e4009
https://pubmed.ncbi.nlm.nih.gov/30257642
https://pubmed.ncbi.nlm.nih.gov/30257642
Autor:
Yukun Chen, Benjamin D. Colvard, Jonathan Nguyen, Rajiv G. Agrawal, Ryan J. Hogue, Ari E. Berman, Yazan M. Al-Hasan, Anna Kate Fowler, Patricia S. Levin, Peter J. Syapin, Yuri A. Blednov, Susan E. Bergeson, Oscar Velasquez, Aveline Hewetson, Scott R. Franklin, Chris Walz, Julie A. Owen
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:428-437
Alcoholism is a complex trait involving the interaction of numerous biological and environmental factors. In the past several decades, researchers have convincingly elucidated that, for a disease of such complexity as alcoholism, no single molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15448687b1dade0961634c59008905a
https://doi.org/10.1111/acer.12288
https://doi.org/10.1111/acer.12288
Autor:
Loren P. Thompson, Gerard A. Pinkas, Hongshan Liu, LaShauna C. Evans, Kazumasa Hashimoto, Yazan M. Al-Hasan
Publikováno v:
Reproductive Sciences. 19:1001-1009
Chronic exposure to hypoxia during pregnancy generates a stressed intrauterine environment that may lead to fetal organ damage. The objectives of the study are (1) to quantify the effect of chronic hypoxia in the generation of oxidative stress in fet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720c8036192c65c4d8f6f70832b3b8d9
https://doi.org/10.1177/1933719112440052
https://doi.org/10.1177/1933719112440052
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:24-34
Background: A prevailing hypothesis is that the set of genes that underlie the endophenotypes of alcoholism overlap with those responsible for the addicted state. Functional ethanol tolerance, an endophenotype of alcoholism, is defined as a reduced r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cb0845530b2a70e1d478845e59c0f0
https://doi.org/10.1111/j.1530-0277.2011.01587.x
https://doi.org/10.1111/j.1530-0277.2011.01587.x
Autor:
Nigel S. Atkinson, Alfredo Ghezzi, Francisco J. Prado, Roseanna B. Robles, Yazan M. Al-Hasan, Harish R. Krishnan
Publikováno v:
Behavior Genetics. 41:734-745
The hypnotic effects of anesthetics are caused by their interactions with neuronal components vital for proper signaling. An understanding of the adaptive mechanisms that lead to the development of anesthetic tolerance can offer insight into the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947aa689903d0265731d75fe61ff6726
https://doi.org/10.1007/s10519-011-9451-8
https://doi.org/10.1007/s10519-011-9451-8
Publikováno v:
Proceedings of the National Academy of Sciences. 101:17276-17281
Changes in neural activity caused by exposure to drugs may trigger homeostatic mechanisms that attempt to restore normal neural excitability. In Drosophila , a single sedation with the anesthetic benzyl alcohol changes the expression of the slo K + c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01c594b195c0887d6976f5dc0504e3f
https://doi.org/10.1073/pnas.0405584101
https://doi.org/10.1073/pnas.0405584101