Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yayoi OBATA"'
Autor:
Shinya IKEDA, Koki TANAKA, Reiko OHTANI, Akifumi KANDA, Yusuke SOTOMARU, Tomohiro KONO, Yayoi OBATA
Publikováno v:
The Journal of Reproduction and Development, Vol 68, Iss 2, Pp 125-136 (2022)
In the male germline, the machinery to repress retrotransposons that threaten genomic integrity via the piRNA pathway is established in gonocytes. It has been reported that disruption of the piRNA pathway leads to activation of retrotransposons and a
Externí odkaz:
https://doaj.org/article/5d74fd8e88ef4cfa8f8cee2f05a201b6
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 5, Pp 327-331 (2021)
Mammalian ovaries contain a large number of immature follicles. Follicular culture can contribute to the production of fertile oocytes from latent immature follicles, providing a useful tool for exploring the developmental competencies and related fa
Externí odkaz:
https://doaj.org/article/dfa9c980fcb34745a9159c9316a98819
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 3, Pp 229-234 (2021)
Conditional knockout technology is a powerful tool for investigating the spatiotemporal functions of target genes. However, generation of conditional knockout mice involves complicated breeding programs and considerable time. A recent study has shown
Externí odkaz:
https://doaj.org/article/e33b7d63a2c64ac0a70e153e9338a798
Autor:
Yayoi Obata, Kazuma Murakami, Taiji Kawase, Kenji Hirose, Naotaka Izuo, Takahiko Shimizu, Kazuhiro Irie
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21531-21537 (2020)
Externí odkaz:
https://doaj.org/article/fb417b04a9af4aa3b1597a9b183e48de
Publikováno v:
Histochemistry and Cell Biology. 157:333-345
In vitro systems capable of reconstituting the process of mouse oogenesis are now being established to help develop further understanding of the mechanisms underlying oocyte/follicle development and differentiation. These systems could also help incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79b280587958550aafd132ffcda5114
https://doi.org/10.1007/s00418-021-02058-w
https://doi.org/10.1007/s00418-021-02058-w
Publikováno v:
Reproduction (Cambridge, England)
In vitro generation of fertile oocytes has been reported in several mammalian species. However, oocyte integrity is compromised by in vitro culture. Here, we aimed to understand the factors affecting oocyte competency by evaluating mitochondrial func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d7e2b1e5d112ae8ab249bb8183a815
https://doi.org/10.1530/rep-21-0209
https://doi.org/10.1530/rep-21-0209
Publikováno v:
Journal of Reproduction and Development. 67:229-234
Conditional knockout technology is a powerful tool for investigating the spatiotemporal functions of target genes. However, generation of conditional knockout mice involves complicated breeding programs and considerable time. A recent study has shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81486082482f4b4b57586996d258ce68
https://doi.org/10.1262/jrd.2020-146
https://doi.org/10.1262/jrd.2020-146
Publikováno v:
The Journal of Reproduction and Development
Mammalian ovaries contain a large number of immature follicles. Follicular culture can contribute to the production of fertile oocytes from latent immature follicles, providing a useful tool for exploring the developmental competencies and related fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ac48e19dae49582cb6aa15a54e0179
https://doi.org/10.1262/jrd.2021-091
https://doi.org/10.1262/jrd.2021-091
Autor:
Takahiko Shimizu, Taiji Kawase, Kazuma Murakami, Kazuhiro Irie, Yayoi Obata, Naotaka Izuo, Kenji Hirose
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21531-21537 (2020)
RNA aptamers have garnered attention for diagnostic applications due to their ability to recognize diverse targets. Oligomers of 42-mer amyloid β-protein (Aβ42), whose accumulation is relevant to the pathology of Alzheimer's disease (AD), are among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb0a56847e8923085be74435b03f9da
https://doaj.org/article/fb417b04a9af4aa3b1597a9b183e48de
https://doaj.org/article/fb417b04a9af4aa3b1597a9b183e48de
Autor:
Naotaka Izuo, Yayoi Obata, Kazuma Murakami, Haruka Ueda, Takahiko Shimizu, Tatsuya Awano, Kazuhiro Irie, Asa Sekikawa, Keiji Takabe
Publikováno v:
J Biol Chem
Oligomers of β-amyloid 42 (Aβ42), rather than fibrils, drive the pathogenesis of Alzheimer's disease (AD). In particular, toxic oligomeric species called protofibrils (PFs) have attracted significant attention. Herein, we report RNA aptamers with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f993f34e3039dc1b7b9b9028c9d5ddf
https://doi.org/10.1074/jbc.ra119.010955
https://doi.org/10.1074/jbc.ra119.010955