Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yayoi Nomura"'
Autor:
Fei Jin, Minxuan Sun, Takashi Fujii, Yurika Yamada, Jin Wang, Andrés D Maturana, Miki Wada, Shichen Su, Jinbiao Ma, Hironori Takeda, Tsukasa Kusakizako, Atsuhiro Tomita, Yoshiko Nakada-Nakura, Kehong Liu, Tomoko Uemura, Yayoi Nomura, Norimichi Nomura, Koichi Ito, Osamu Nureki, Keiichi Namba, So Iwata, Ye Yu, Motoyuki Hattori
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001231 (2021)
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed-state, and structure-based fu
Externí odkaz:
https://doaj.org/article/1ea7be941cf6441f841a041603748098
Autor:
Jinta Asami, Kanako Terakado Kimura, Yoko Fujita-Fujiharu, Hanako Ishida, Zhikuan Zhang, Yayoi Nomura, Kehong Liu, Tomoko Uemura, Yumi Sato, Masatsugu Ono, Masaki Yamamoto, Takeshi Noda, Hideki Shigematsu, David Drew, So Iwata, Toshiyuki Shimizu, Norimichi Nomura, Umeharu Ohto
Publikováno v:
Nature. 606:1021-1026
Chronic infection with hepatitis B virus (HBV) affects more than 290 million people worldwide, is a major cause of cirrhosis and hepatocellular carcinoma, and results in an estimated 820,000 deaths annually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4781eb3c3355fe40aa3b2d2a8f2f072
https://doi.org/10.1038/s41586-022-04845-4
https://doi.org/10.1038/s41586-022-04845-4
Autor:
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, Yayoi Nomura, Rosemary Menzies, Masaki Tajima, Koji Kitaoka, Yasuharu Haku, Sara Delghandi, Keiko Yurimoto, Fumihiko Matsuda, So Iwata, Toshihiko Ogura, Sidonia Fagarasan, Tasuku Honjo
Publikováno v:
Science (New York, N.Y.). 378(6618)
Spermidine (SPD) delays age-related pathologies in various organisms. SPD supplementation overcame the impaired immunotherapy against tumors in aged mice by increasing mitochondrial function and activating CD8 + T cells. Treatment of naïve CD8 + T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd036778ce1fcdf297c7d3c795da9ee
https://pubmed.ncbi.nlm.nih.gov/36387057
https://pubmed.ncbi.nlm.nih.gov/36387057
Autor:
Tatsuro Shimamura, So Iwata, Takatoshi Arakawa, Dohyun Im, Hidetsugu Asada, Kanako Terakado Kimura, Francois Marie Ngako Kadji, Kunio Hirata, Junken Aoki, Norimichi Nomura, Asuka Inoue, Yayoi Nomura, Chihiro Mori
Publikováno v:
Nature Structural & Molecular Biology. 26:121-128
Many drugs target the serotonin 2A receptor (5-HT2AR), including second-generation antipsychotics that also target the dopamine D2 receptor (D2R). These drugs often produce severe side effects due to non-selective binding to other aminergic receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1fb1fbcbe2f222d4cf2c240384417a
https://doi.org/10.1038/s41594-018-0180-z
https://doi.org/10.1038/s41594-018-0180-z
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611258
Fv and Fab antibody fragments are versatile co-crystallization partners that aid in the structural determination of otherwise "uncrystallizable" proteins, including human/mammalian membrane proteins. Accessible methods for the rapid and reliable prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c92e067e73929a4849544157d7cf2f7
https://doi.org/10.1007/978-1-0716-1126-5_5
https://doi.org/10.1007/978-1-0716-1126-5_5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2247
Fv and Fab antibody fragments are versatile co-crystallization partners that aid in the structural determination of otherwise "uncrystallizable" proteins, including human/mammalian membrane proteins. Accessible methods for the rapid and reliable prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a46be3b9c16e3ca908af20121d840bb
https://pubmed.ncbi.nlm.nih.gov/33301113
https://pubmed.ncbi.nlm.nih.gov/33301113
Autor:
Takashi Fujii, Miki Wada, Jun-Song Wang, Yayoi Nomura, Andrés D. Maturana, Tsukasa Kusakizako, Yurika Yamada, So Iwata, Osamu Nureki, Yoshiko Nakada-Nakura, Atsuhiro Tomita, Motoyuki Hattori, Jie Ma, Keiichi Namba, Kei K. Ito, Minxuan Sun, H. Takeda, Fei Jin, Tomoko Uemura, Shichen Su, Norimichi Nomura, Ye Yu, Kehong Liu
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed state and structure-based fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee246f6a6872896253039229e7be2e3
https://doi.org/10.1101/2020.08.27.270991
https://doi.org/10.1101/2020.08.27.270991
Publikováno v:
Protein Science. 27:1038-1046
Tumor necrosis factor α (TNFα) is a proinflammatory cytokine, and elevated levels of TNFα in serum are associated with various autoimmune diseases, including rheumatoid arthritis (RA), ankylosing spondylitis (AS), Crohn's disease (CD), psoriasis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc4ea26518ea5b1b26dfeea30ea3dc3
https://doi.org/10.1002/pro.3407
https://doi.org/10.1002/pro.3407
Publikováno v:
Protein Science. 25(12):2268-2276
Fv antibody fragments have been used as co-crystallization partners in structural biology, particularly in membrane protein crystallography. However, there are inherent technical issues associated with the large-scale production of soluble, functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f134fc5fef2ca528f9e09de72b9882
http://hdl.handle.net/2433/216542
http://hdl.handle.net/2433/216542
Publikováno v:
Methods in enzymology. 629
The programmed death 1 (PD-1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) are negative regulators of T-cell immune function. Removal of these "brakes" in T cells results in increased activation of the immune system and controlling and er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3218453e99b7b46854c8f09508a9976f
https://pubmed.ncbi.nlm.nih.gov/31727250
https://pubmed.ncbi.nlm.nih.gov/31727250