Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yayoi Natsume"'
Autor:
Mei Tomoto, Yohei Mineharu, Noriaki Sato, Yoshinori Tamada, Mari Nogami-Itoh, Masataka Kuroda, Jun Adachi, Yoshito Takeda, Kenji Mizuguchi, Atsushi Kumanogoh, Yayoi Natsume-Kitatani, Yasushi Okuno
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by severe lung fibrosis and a poor prognosis. Although the biomolecules related to IPF have been extensively studied, molecular mechanisms of the pathogenesis and the
Externí odkaz:
https://doaj.org/article/046eef4039e1435694fbc33987598267
Autor:
Satoshi Kozawa, Kengo Tejima, Shunki Takagi, Masataka Kuroda, Mari Nogami-Itoh, Hideya Kitamura, Takashi Niwa, Takashi Ogura, Yayoi Natsume-Kitatani, Thomas N. Sato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease characterized by complex lung pathogenesis affecting approximately three million people worldwide. While the molecular and cellular details of the IPF mechanism is emer
Externí odkaz:
https://doaj.org/article/1030cbd97fb94eb3b9cb7eeb4bde49c2
Autor:
Michiru Otaki, Nozomi Hirane, Yayoi Natsume-Kitatani, Mari Nogami Itoh, Masanori Shindo, Yoichi Kurebayashi, Shin-Ichiro Nishimura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract This study presents “mouse tissue glycome atlas” representing the profiles of major N-glycans of mouse glycoproteins that may define their essential functions in the surface glycocalyx of mouse organs/tissues and serum-derived extracellu
Externí odkaz:
https://doaj.org/article/5de9196a41814d5181581bf61c051185
Autor:
Koji Hosomi, Mayu Saito, Jonguk Park, Haruka Murakami, Naoko Shibata, Masahiro Ando, Takahiro Nagatake, Kana Konishi, Harumi Ohno, Kumpei Tanisawa, Attayeb Mohsen, Yi-An Chen, Hitoshi Kawashima, Yayoi Natsume-Kitatani, Yoshimasa Oka, Hidenori Shimizu, Mari Furuta, Yoko Tojima, Kento Sawane, Azusa Saika, Saki Kondo, Yasunori Yonejima, Haruko Takeyama, Akira Matsutani, Kenji Mizuguchi, Motohiko Miyachi, Jun Kunisawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Here, the authors inversely associate Blautia wexlerae with obesity and type 2 diabetes mellitus in humans and further show that administration of B. wexlerae to mice decrease both high-fat diet–induced obesity and diabetes via modulating gut micro
Externí odkaz:
https://doaj.org/article/17725b6c6ae24b218512afb8a846b033
Autor:
Kou Hioki, Tomoya Hayashi, Yayoi Natsume-Kitatani, Kouji Kobiyama, Burcu Temizoz, Hideo Negishi, Hitomi Kawakami, Hiroyuki Fuchino, Etsushi Kuroda, Cevayir Coban, Nobuo Kawahara, Ken J. Ishii
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adjuvants are important vaccine components, composed of a variety of chemical and biological materials that enhance the vaccine antigen-specific immune responses by stimulating the innate immune cells in both direct and indirect manners to produce a
Externí odkaz:
https://doaj.org/article/fa80452d68f5493aa0a8cbec10a8eb4d
Autor:
Reiko Watanabe, Toshio Kawata, Shinya Ueda, Takumi Shinbo, Mitsuo Higashimori, Yayoi Natsume-Kitatani, Kenji Mizuguchi
Publikováno v:
Molecular pharmaceutics. 20(1)
The contribution ratio of metabolic enzymes such as cytochrome P450 to
Autor:
Rodolfo S. Allendes Osorio, Johan T. Nyström-Persson, Yosui Nojima, Yuji Kosugi, Kenji Mizuguchi, Yayoi Natsume-Kitatani
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04618- (2020)
Multi-omics analyses, combining transcriptomics, genomics, proteomics, and so on, have led to important insights in many areas of biology and medicine. To support these analyses, software that can handle the difficulties associated with multi-omics d
Externí odkaz:
https://doaj.org/article/2b9468d5957346cbbe0cec5907358381
Autor:
Yi-An Chen, Jonguk Park, Yayoi Natsume-Kitatani, Hitoshi Kawashima, Attayeb Mohsen, Koji Hosomi, Kumpei Tanisawa, Harumi Ohno, Kana Konishi, Haruka Murakami, Motohiko Miyachi, Jun Kunisawa, Kenji Mizuguchi
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243609 (2020)
With an ever-increasing interest in understanding the relationships between the microbiota and the host, more tools to map, analyze and interpret these relationships have been developed. Most of these tools, however, focus on taxonomic profiling and
Externí odkaz:
https://doaj.org/article/8c1a3ec1025a487588dd28cc0c59a092
Autor:
Koji Hosomi, Harumi Ohno, Haruka Murakami, Yayoi Natsume-Kitatani, Kumpei Tanisawa, Soichiro Hirata, Hidehiko Suzuki, Takahiro Nagatake, Tomomi Nishino, Kenji Mizuguchi, Motohiko Miyachi, Jun Kunisawa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Metagenomic analysis based on the 16S rRNA gene is generally performed to examine the diversity and abundance of commensal bacteria in feces, which is now recognized to be associated with human health and diseases. Guanidine thiocyanate (GuS
Externí odkaz:
https://doaj.org/article/07d42677e3be4d0297d5529ed4dcc5d1
Autor:
Johan Nyström-Persson, Yayoi Natsume-Kitatani, Yoshinobu Igarashi, Daisuke Satoh, Kenji Mizuguchi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Toxygates was originally released as a user-friendly interface to enhance the accessibility of the large-scale toxicogenomics database, Open TG-GATEs, generated by the Japanese Toxicogenomics Project. Since the original release, significant
Externí odkaz:
https://doaj.org/article/1884fb74a1b94882b11cd136fbe69ccf