Výsledky vyhledávání - "Yayoi Kurota"

Formation of α-Aminoadipic and γ-Glutamic Semialdehydes in Proteins by the Maillard Reaction

Autor: Yayoi Kurota, Mitsugu Akagawa, Daisuke Sasaki, Kyozo Suyama

Publikováno v: Annals of the New York Academy of Sciences. 1043:129-134

Recent research has demonstrated that nonenzymatic glycation (the Maillard reaction) lead to the formation of carbonyl groups and advanced glycation end products (AGEs) in proteins. Such oxidative modifications are a major contributing factor to diab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de30e4a3f04d16625fcfffd7a7a5f67
https://doi.org/10.1196/annals.1333.016

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New method for the quantitative determination of major protein carbonyls, alpha-aminoadipic and gamma-glutamic semialdehydes: investigation of the formation mechanism and chemical nature in vitro and in vivo

Autor: Koji Uchida, Daisuke Sasaki, Yayoi Kurota, Kyozo Suyama, Mitsugu Akagawa, Mari Yotsu-Yamashita, Yoshihisa Ishii

Publikováno v: Chemical research in toxicology. 19(8)

Alpha-aminoadipic semialdehyde (AAS) and gamma-glutamic semialdehyde (GGS) are identified as the major carbonyl products in oxidized proteins. To elucidate the formation pathway of AAS and GGS in vivo, we developed and validated a new quantification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9922cca2c5115d6084c38a2dd28088e
https://pubmed.ncbi.nlm.nih.gov/16918245

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