Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Yayoi Izu"'
Autor:
Mengjie Zhu, Fabian Metzen, Mark Hopkinson, Janina Betz, Juliane Heilig, Jassi Sodhi, Thomas Imhof, Anja Niehoff, David E. Birk, Yayoi Izu, Marcus Krüger, Andrew A. Pitsillides, Janine Altmüller, Gerjo J.V.M. van Osch, Volker Straub, Gudrun Schreiber, Mats Paulsson, Manuel Koch, Bent Brachvogel
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107225- (2023)
Summary: Collagen XII, belonging to the fibril-associated collagens, is a homotrimeric secreted extracellular matrix (ECM) protein encoded by the COL12A1 gene. Mutations in the human COL12A1 gene cause an Ehlers-Danlos/myopathy overlap syndrome leadi
Externí odkaz:
https://doaj.org/article/9b9be6f40bdd4d2e8ab523d6005f0342
Autor:
Yayoi Izu, David E. Birk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Collagen XII, a fibril-associated collagen with interrupted triple helices (FACIT), influences fibrillogenesis in numerous tissues. In addition to this extracellular function, collagen XII also directly regulates cellular function. Collagen XII is wi
Externí odkaz:
https://doaj.org/article/192d0e699eb94385b5403d8a0281cfd1
Autor:
Rolen M. Quadros, Hiromi Miura, Donald W. Harms, Hisako Akatsuka, Takehito Sato, Tomomi Aida, Ronald Redder, Guy P. Richardson, Yutaka Inagaki, Daisuke Sakai, Shannon M. Buckley, Parthasarathy Seshacharyulu, Surinder K. Batra, Mark A. Behlke, Sarah A. Zeiner, Ashley M. Jacobi, Yayoi Izu, Wallace B. Thoreson, Lisa D. Urness, Suzanne L. Mansour, Masato Ohtsuka, Channabasavaiah B. Gurumurthy
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Conditional knockout mice and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are key for many genetic studies and comprise over 90% of mouse models created. Conditional knockout mice a
Externí odkaz:
https://doaj.org/article/cc09dd43b09b4403b9ad7415943adf1e
Autor:
Jumpei Shirakawa, Shuhei Kajikawa, Ralph T Böttcher, Mercedes Costell, Yayoi Izu, Tadayoshi Hayata, Masaki Noda, Yoichi Ezura
Publikováno v:
JBMR Plus, Vol 3, Iss 6, Pp n/a-n/a (2019)
ABSTRACT Profilin 1 (Pfn1), a regulator of actin polymerization, controls cell movement in a context‐dependent manner. Pfn1 supports the locomotion of most adherent cells by assisting actin‐filament elongation, as has been shown in skeletal proge
Externí odkaz:
https://doaj.org/article/3907a79a6c0d454a8173717a14fa1659
Autor:
Manuel Koch, Louis J. Soslowsky, David E. Birk, Brianne K. Connizzo, Yayoi Izu, Sheila M. Adams, David P. Beason
Publikováno v:
Matrix Biol
Tendons have a uniaxially aligned structure with a hierarchical organization of collagen fibrils crucial for tendon function. Collagen XII is expressed in tendons and has been implicated in the regulation of fibrillogenesis. It is a non-fibrillar col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f191944a8ffb64001a50032ec197478
https://doi.org/10.1016/j.matbio.2020.10.004
https://doi.org/10.1016/j.matbio.2020.10.004
Publikováno v:
Journal of Bone and Mineral Metabolism.
Profilin-1 (Pfn1), an evolutionarily conserved actin-binding protein, is an important regulator of the cytoskeleton. We previously reported the osteoclast-specific Pfn1-conditional knockout (cKO) mice had postnatal osteolytic phenotype with craniofac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05e75ba1f4715ef70b994c34c848616
https://doi.org/10.1007/s00774-022-01320-y
https://doi.org/10.1007/s00774-022-01320-y
Autor:
Mengjie Zhu, Fabian Metzen, Janina Betz, Mark Hopkinson, Juliane Heilig, Thomas Imhof, Anja Niehoff, David E. Birk, Yayoi Izu, Andrew A. Pitsillides, Janine Altmüller, Gudrun Schreiber, Mats Paulsson, Manuel Koch, Bent Brachvogel
Collagen XII, belonging to the fibril-associated collagens with interrupted triple helix (FACIT) family, assembles from three identical α-chains encoded by the COL12A1 gene. The trimeric molecule consists of three N-terminal noncollagenous NC3 domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480b08f2f9aeb1d335b54394b0a88a2d
https://doi.org/10.1101/2021.12.29.474475
https://doi.org/10.1101/2021.12.29.474475
Autor:
Taiju Yoneda, Kazuo Kaneko, Masashi Nagao, Muneaki Ishijima, Kei Fujihara, Yayoi Izu, Manuel Koch, Shin Fukusato, Kiyotaka Arai
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 4051, p 4051 (2021)
Volume 10
Issue 18
Journal of Clinical Medicine, Vol 10, Iss 4051, p 4051 (2021)
Volume 10
Issue 18
Anterior cruciate ligament (ACL) rupture is a common knee injury for athletes. Although surgical reconstruction is recommended for the treatment of ACL ruptures, 100% functional recovery is unlikely. Therefore, the discovery of risk factors for ACL r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0490bab7c8b2466dfa88d53cb534da9e
https://pubmed.ncbi.nlm.nih.gov/34575162
https://pubmed.ncbi.nlm.nih.gov/34575162
Autor:
Ralph T. Böttcher, Wanting Lin, Keiji Moriyama, Yayoi Izu, Makiri Kawasaki, Mercedes Costell, Arayal Smriti, Chantida Pawaputanon, Yoichi Ezura, Masaki Noda
Publikováno v:
Journal of Cellular Physiology. 233:259-268
Osteocytes are the most abundant cells in bone and regulate bone metabolism in coordination with osteoblasts and osteoclasts. However, the molecules that control osteocytes are still incompletely understood. Profilin1 is an actin-binding protein that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc2ae4b0c461f654c47d2637f7c9bed
https://doi.org/10.1002/jcp.25872
https://doi.org/10.1002/jcp.25872
Autor:
Yutaka Inagaki, Suzanne L. Mansour, Ronald Redder, Parthasarathy Seshacharyulu, Guy P. Richardson, Daisuke Sakai, Mark A. Behlke, Masato Ohtsuka, Hisako Akatsuka, Rolen M. Quadros, Channabasavaiah B. Gurumurthy, Lisa D. Urness, Tomomi Aida, Donald W. Harms, Takehito Sato, Wallace B. Thoreson, Shannon M. Buckley, Yayoi Izu, Sarah A. Zeiner, Hiromi Miura, Ashley M. Jacobi, Surinder K. Batra
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Genome Biology
Genome Biology
Background Conditional knockout mice and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are key for many genetic studies and comprise over 90% of mouse models created. Conditional knockout mice are genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18d729e2d7fc752e6730f9c4382957e
http://link.springer.com/article/10.1186/s13059-017-1220-4
http://link.springer.com/article/10.1186/s13059-017-1220-4