Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Yayi He"'
Autor:
Yuting Chen, Chenchen Guo, Xinlei Cai, Liang Hu, Xinyuan Tong, Yun Xue, Qiqi Zhao, Tengfei Zhang, Yuan Chen, Yongting Fang, Yayi He, Yan Li, Bin Zhou, Hongbin Ji
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/ad0dd4c7332240258328ca9676baf815
Autor:
Xinyue Liu, Yan Kong, Youwen Qian, Haoyue Guo, Lishu Zhao, Hao Wang, Kandi Xu, Li Ye, Yujin Liu, Hui Lu, Yayi He
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102143- (2024)
Tumor-infiltrating lymphocytes (TILs) are essential components of the tumor microenvironment (TME) of non-small cell lung cancer (NSCLC). Still, it is difficult to describe due to their heterogeneity. In this study, five cell markers from NSCLC patie
Externí odkaz:
https://doaj.org/article/ceebaaa32b9e4abf9a59a22ef910c20f
Autor:
Si Wang, Ping Chen, Yayi He, Jing Wei, Li Tian, Yajun Wu, Hongjun Lv, Xiaogang Peng, Xingru Zhang, Bingyin Shi, Qian Wu
Publikováno v:
BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Hypothyroidism is a major manifestation of autoimmune thyroid diseases (AITD). We previously reported that a low selenium (Se) status was linked to an elevated prevalence of thyroid diseases. We hypothesized that Se status may als
Externí odkaz:
https://doaj.org/article/564746439e12402a89741b386afbff2c
Autor:
Chen Tang, Shaliu Fu, Xuan Jin, Wannian Li, Feiyang Xing, Bin Duan, Xiaojie Cheng, Xiaohan Chen, Shuguang Wang, Chenyu Zhu, Gaoyang Li, Guohui Chuai, Yayi He, Ping Wang, Qi Liu
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background The precise characterization of individual tumors and immune microenvironments using transcriptome sequencing has provided a great opportunity for successful personalized cancer treatment. However, the cancer treatment response is
Externí odkaz:
https://doaj.org/article/37d4a4c93ee148e494c50e012bd820c5
Autor:
Peixin Chen, Chenglong Sun, Hao Wang, Wencheng Zhao, Yan Wu, Haoyue Guo, Caicun Zhou, Yayi He
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-14 (2023)
Abstract Immunotherapy is considered a major breakthrough in the treatment of small cell lung cancer (SCLC), although its anti-tumor efficacy is limited. With a high degree of malignancy and high heterogeneity, SCLC is difficult to treat in the clini
Externí odkaz:
https://doaj.org/article/f37ecae6a0044fbaa5d24017e0ded88e
Autor:
Jing Zhao, Jie Zhao, Xue Yang, Yang Xia, Yayi He, Kun Huang, Liang Zeng, Yongchang Zhang, Jiaqi Zhou, Yin Zhu, Yi Gao, Panwen Tian, Qiyuan Wang, Mailin Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background Small cell lung cancer (SCLC) is a highly malignant cancer characterized by metastasis and an extremely poor prognosis. Although combined chemoimmunotherapy improves the prognosis of extensive-stage (ES)-SCLC, the survival benefits remain
Externí odkaz:
https://doaj.org/article/58ba7ff50e1d4f1dbd685354be63cb87
Autor:
Yayi He, Haoyue Guo, Li Diao, Yu Chen, Junjie Zhu, Hiran C. Fernando, Diego Gonzalez Rivas, Hui Qi, Chunlei Dai, Xuzhen Tang, Jun Zhu, Jiawei Dai, Kan He, Dan Chan, Yang Yang
Publikováno v:
Engineering, Vol 15, Iss , Pp 102-114 (2022)
Patient-derived tumor xenografts (PDXs) are a powerful tool for drug discovery and screening in cancer. However, current studies have led to little understanding of genotype mismatches in PDXs, leading to massive economic losses. Here, we established
Externí odkaz:
https://doaj.org/article/ff5be0d86a244933aa0d0e66330b5f06
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 10, Pp 1203-1212 (2022)
Abstract. Immunotherapy that targets checkpoints, especially programmed cell death protein 1 and programmed cell death ligand 1, has revolutionized cancer therapy regimens. The overall response rate to mono-immunotherapy, however, is limited, emphasi
Externí odkaz:
https://doaj.org/article/6a93b3a2014d48acab7f624cd589a901
Autor:
Minlin Jiang, Keyi Jia, Lei Wang, Wei Li, Bin Chen, Yu Liu, Hao Wang, Sha Zhao, Yayi He, Caicun Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Genomic instability remains an enabling feature of cancer and promotes malignant transformation. Alterations of DNA damage response (DDR) pathways allow genomic instability, generate neoantigens, upregulate the expression of programmed death ligand 1
Externí odkaz:
https://doaj.org/article/88e5278e54074b1e9bcce509a15496a1
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 16 (2022)
Background: Low baseline prognostic nutritional index (PNI) scores are associated with poor survival for various malignancies; however, they vary based on the cohort and time resulting in inaccurate results. We determined the predictive value of the
Externí odkaz:
https://doaj.org/article/afac06d8c0f54882ba8d61c80e72e87a