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Akademický článek

Chemical Fingerprinting and Quantification of Chinese Cinnamomi Cortex by Ultra High Performance Liquid Chromatography Coupled with Chemometrics Methods

Autor: Ninghui Ma, Yue Ding, Yong Zhang, Tong Zhang, Yaxiong Yi, Bing Wang

Publikováno v: Molecules, Vol 23, Iss 9, p 2214 (2018)

To rapidly clarify and quantify the chemical profiling of Cinnamomi cortex a reliable and feasible strategy of chromatographic fingerprinting with a suite of chemometrics methods was developed and validated by ultra-high performance liquid chromatogr

Externí odkaz: https://doaj.org/article/22c53b2804d648e2a0a3a34c05cd23e4

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Quantitative Analysis of Twelve Active Components Combined With Chromatographic Fingerprint for Comprehensive Evaluation of Qinma Prescription by Ultra-Performance Liquid Chromatography Coupled With Diode Array Detection

Autor: Tong Zhang, Juanjuan Tian, Yaxiong Yi, Yi Chen, Ting Li, Yue Ding, Yi Zhang, Xiao-Yi Jiang, Lijuan Zhang, Ping Kang

Publikováno v: Journal of Chromatographic Science. 57:855-865

A combination method of ultra-performance liquid chromatography (UPLC) coupled with diode array detection has been developed for quality evaluation of Qinma prescription (QMP), based on chromatographic fingerprint technology with the similarity analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bf9519a73c7e25eabc9b339dd63fac
https://doi.org/10.1093/chromsci/bmz060

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pH-sensitive and biocompatible quercetin-loaded GO–PEA–HA carrier improved antitumour efficiency and specificity

Autor: Qi Zhang, Xing Huang, Yaxiong Yi, Tong Zhang, Bing Wang, Yiqiong Pu

Publikováno v: Artificial Cells, Nanomedicine, and Biotechnology. 46:28-37

A novel drug carrier was designed based on a new biomaterial, that is, graphene oxide (GO), to improve the efficiency and specificity of anticancer drug. In this study, GO was successively modified with polyetheramine (PEA) and hyaluronic acid (HA).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618e0cba57f37744cb17c7d6524ded05
https://doi.org/10.1080/21691401.2018.1489261

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Metabolism profiles of icariin in rats using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and in vitro enzymatic study

Autor: Han Han, Tao Cheng, Yaxiong Yi, Tingting Sheng, Tong Zhang

Publikováno v: Journal of Chromatography B. :353-360

Icariin (ICA), the major constituent of Epimedium brevicornu Maxim, is recognized as an effective agent for the treatment of osteoporosis. In our previous report, the relatively short half-life (74min) and poor bioavailability (approximately 0.1%) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e367de90cc8e6c53edc998e3ba3cc9
https://doi.org/10.1016/j.jchromb.2016.09.010

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Stereoselective pharmacokinetic and metabolism studies of 20(S)- and 20(R)-ginsenoside Rg3 epimers in rat plasma by liquid chromatography-electrospray ionization mass spectrometry

Autor: Ming Peng, Tong Zhang, Xiaonan Li, Yue Ding, Yongjian Yang, Jian Le, Xijing Chen, Yaxiong Yi

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 121:215-224

20(S)- and 20(R)-ginsenoside Rg3 are a pair of epimers which could be deglycosylated to ginsenoside Rh2 and protopanaxadiol (PPD) in vivo. To better understand the differences of pharmacokinetic parameters and metabolism behaviors of Rg3 epimers in r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b87b5415512a2d743372dc94471c3df3
https://doi.org/10.1016/j.jpba.2016.01.020

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Structure-based prediction of CAD response factors of dammarane-type tetracyclic triterpenoid saponins and its application to the analysis of saponin contents in raw and processed Panax notoginseng

Autor: Tong Zhang, Ming Peng, Jian Le, Yaxiong Yi, Yue Ding, Yongjian Yang

Publikováno v: RSC Advances. 6:36987-37005

The analysis of saponin contents in Panax notoginseng (Sanqi) is challenged by the lack of authentic reference standards. In this study, a gradient eluted HPLC method coupled with charged aerosol detector (CAD) has been established to solve this prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9844142176bbb23021a1281f88fb0b65
https://doi.org/10.1039/c6ra03193e

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Chemical Fingerprinting and Quantification of Chinese Cinnamomi Cortex by Ultra High Performance Liquid Chromatography Coupled with Chemometrics Methods

Autor: Tong Zhang, Yong Zhang, Yaxiong Yi, Ning-Hui Ma, Bing Wang, Yue Ding

Publikováno v: Molecules, Vol 23, Iss 9, p 2214 (2018)
Molecules
Volume 23
Issue 9
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e084e566835bfe9084fd667ea0130140
http://www.mdpi.com/1420-3049/23/9/2214

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Yinchenhao Decoction Ameliorates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis in Rats by Regulating Phase II Metabolic Enzymes and Transporters

Autor: Feng Shi, Tong Zhang, Yong Zhang, Ning-Hui Ma, Ping Kang, Zhen-Zhen Cai, Yaxiong Yi, Yue Ding

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)

Yinchenhao Decoction (YCHD), a famous traditional Chinese formula, has been used for treating cholestasis for 1000s of years. The cholagogic effect of YCHD has been widely reported, but its pharmacodynamic material and underlying therapeutic mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167222b5256ff1b1229a294fbc072b10
https://pubmed.ncbi.nlm.nih.gov/29867509

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Simultaneous quantitation of 14 active components in Yinchenhao decoction with an ultrahigh performance liquid chromatography-diode array detector: Method development and ingredient analysis of different commonly prepared samples

Autor: Tong Zhang, XiaoJun Xu, YuXin Zhang, Yuan Zhao, Lu Lu, Yaxiong Yi, Yong Zhang, Yue Ding

Publikováno v: Journal of separation science. 39(21)

J. Sep. Sci. 2016, 39, 4147-4157 DOI: 10.1002/jssc.201600284 Yinchenhao decoction (YCHD) is a famous Chinese herbal formula recorded in the Shang Han Lun which was prescribed by Zhongjing Zhang during 150-219 AD. A novel quantitative analysis method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f7640ae3fe82f8483d046c025ba2e3
https://pubmed.ncbi.nlm.nih.gov/27870291

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Simultaneous quantitation of 14 active components in Yinchenhao decoction by using ultra high performance liquid chromatography with diode array detection: Method development and ingredient analysis of different commonly prepared samples

Autor: Tong Zhang, Yong Zhang, Yaxiong Yi, Yuan Zhao, XiaoJun Xu, Yue Ding, Lu Lu, YuXin Zhang

Publikováno v: Journal of separation science. 39(21)

We developed a novel quantitative analysis method based on ultra high performance liquid chromatography coupled with diode array detection for the simultaneous determination of the 14 main active components in Yinchenhao decoction. All components wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5909876c5a07c46a30b95120804b4718
https://pubmed.ncbi.nlm.nih.gov/27673697

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