ILC2-derived CGRP triggers acute inflammation and nociceptive responses in bacterial cystitis

Autor: Zizhuo Yang, Yaxiao Liu, Yinrui Xiang, Rui Chen, Lipeng Chen, Shuai Wang, Linchen Lv, Maolin Zang, Nan Zhou, Shiyang Li, Benkang Shi, Yan Li

Publikováno v: Cell Reports, Vol 43, Iss 10, Pp 114859- (2024)

Summary: Calcitonin gene-related peptide (CGRP), a neuropeptide involved in nociceptor neuronal function, plays a critical role in mediating neuroinflammation and pain. In this study, we find that bladder group 2 innate lymphoid cells (ILC2s) functio

Externí odkaz: https://doaj.org/article/e0a775eca415403fb5281c4219bbdd69

Nociceptor Neurons are Involved in the Host Response to Escherichia coli Urinary Tract Infections

Autor: Zhengdong Gao, Yaxiao Liu, Lekai Zhang, Zizhuo Yang, Linchen Lv, Shuai Wang, Lipeng Chen, Nan Zhou, Yaofeng Zhu, Xuewen Jiang, Benkang Shi, Yan Li

Publikováno v: Journal of Inflammation Research.

Zhengdong Gao,1,2,* Yaxiao Liu,1,2,* Lekai Zhang,1,2 Zizhuo Yang,1,2 Linchen Lv,1,2 Shuai Wang,1,2 Lipeng Chen,1,2 Nan Zhou,1,2 Yaofeng Zhu,1 Xuewen Jiang,1 Benkang Shi,1,2 Yan Li1,2 1Department of Urology, Qilu Hospital of Shandong Universit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca747a04ab98a40767da8e5c2469a0c5
https://www.dovepress.com/nociceptor-neurons-are-involved-in-the-host-response-to-escherichia-co-peer-reviewed-fulltext-article-JIR

Urinary ATP may be a biomarker for bladder outlet obstruction and its severity in patients with benign prostatic hyperplasia

Autor: Xiulin Zhang, Benkang Shi, Shulu Zu, Yaxiao Liu, Yan Li, Mengmeng Zhao, Zhenghao Chen, Shaoyong Wang

Publikováno v: Transl Androl Urol

BACKGROUND: Urothelial cells release ATP into the urine in response to bladder stretch. Urinary ATP concentration in benign prostatic hyperplasia (BPH) patients was higher compared with asymptomatic controls. In this study, we aimed to explore the po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b4da7243e515a84da6b6364d12a4a9
https://doi.org/10.21037/tau.2020.02.18

A force-directed approach to seeking route recommendation in ride-on-demand service using multi-source urban data

Autor: Jingyuan Wang, Xu Ke, Zhiwen Yu, Daqing Zhang, Yan Ding, Chao Chen, Suiming Guo, Yaxiao Liu

Publikováno v: IEEE Transactions on Mobile Computing
IEEE Transactions on Mobile Computing, Institute of Electrical and Electronics Engineers, In press, pp.1-18. ⟨10.1109/tmc.2020.3033274⟩
IEEE Transactions on Mobile Computing, Institute of Electrical and Electronics Engineers, In press, pp.1-18. ⟨10.1109/TMC.2020.3033274⟩

International audience; The rapidly-growing business of ride-on-demand (RoD) service such as Uber, Lyft and Didi proves the effectiveness of their new service model-using mobile apps and dynamic pricing to coordinate between drivers, passengers and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d285ae187b50dffedbf250396acb14
https://hal.archives-ouvertes.fr/hal-03002691

Fine-grained Dynamic Price Prediction in Ride-on-demand Services: Models and Evaluations

Autor: Yaxiao Liu, Jingyuan Wang, Chao Chen, Ke Xu, Dah Ming Chiu, Suiming Guo

Publikováno v: Mobile Networks and Applications. 25:505-520

Ride-on-demand (RoD) services use dynamic prices to balance the supply and demand to benefit both drivers and passengers, as an effort to improve service efficiency. However, dynamic prices also create concerns for passengers: the “unpredictable”

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbb6d747c11cef9ee025840017c4ef5e
https://doi.org/10.1007/s11036-019-01308-5