Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Yaxian Yan"'
Autor:
Xiqian Liu, Likai Ji, Yuqiang Cheng, Linghe Kong, Songhua Xie, Juan Yang, Jiaqi Chen, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Jianhe Sun
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-14 (2024)
Abstract Porcine deltacoronavirus (PDCoV) is an enteropathogenic coronavirus that has been reported to use various strategies to counter the host antiviral innate immune response. The cGAS-STING signalling pathway plays an important role in antiviral
Externí odkaz:
https://doaj.org/article/c1ba2b2962524fa2828da3cc2214b737
Autor:
Qi Shao, Feiyu Fu, Pei Zhu, Xiangyu Yu, Jie Wang, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Yuqiang Cheng, Jianhe Sun
Publikováno v:
Poultry Science, Vol 102, Iss 10, Pp 102954- (2023)
ABSTRACT: Pigeons are considered less susceptible, and display few or no clinical signs to infection with avian influenza virus (AIV). Melanoma differentiation-associated gene 5 (MDA5), an important mediator in innate immunity, has been linked to the
Externí odkaz:
https://doaj.org/article/dfc26e22901f419fadf3088604ed9a45
Autor:
Feiyu Fu, Qi Shao, Jianjian Zhang, Jie Wang, Zhaofei Wang, Jingjiao Ma, Yaxian Yan, Jianhe Sun, Yuqiang Cheng
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The ability of stimulator of interferon genes (STING) to activate interferon (IFN) responses during RNA virus infection has been demonstrated in different mammalian cells. Despite being the host of numerous RNA viruses, the role of STING in bats duri
Externí odkaz:
https://doaj.org/article/c21d38c2a5be408b90aef88ed6733b9d
Autor:
Jie Wang, Yuqiang Cheng, Longlong Wang, Aixi Sun, Zhenyu Lin, Wenxian Zhu, Zhaofei Wang, Jingjiao Ma, Henan Wang, Yaxian Yan, Jianhe Sun
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-14 (2022)
Abstract Innate immunity plays an essential role in preventing the invasion of pathogenic microorganisms. However, innate immunity is a double-edged sword, whose excessive activation is detrimental to immune homeostasis and even leads to a “cytokin
Externí odkaz:
https://doaj.org/article/8a608302d43a4f3e927cd78e2c1078f2
Autor:
Rujuan Wu, Xinyu Zeng, Mingqing Wu, Lixiang Xie, Guanlong Xu, Yaqing Mao, Zhaofei Wang, Yuqiang Cheng, Heng’an Wang, Yaxian Yan, Jianhe Sun, Jingjiao Ma
Publikováno v:
Viruses, Vol 15, Iss 12, p 2365 (2023)
In 2009, a novel H1N1 influenza virus caused the first influenza pandemic of the 21st century. Studies have shown that the influenza M gene played important roles in the pathogenicity and transmissibility of the 2009 H1N1 pandemic ((H1N1)pdm09), whil
Externí odkaz:
https://doaj.org/article/01aa2a3d9d904f058c8bdb49eacc8145
Autor:
Zhenyu Lin, Jie Wang, Nian Zhang, Jianshu Yi, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Kun Qian, Jianhe Sun, Yuqiang Cheng
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-13 (2022)
Abstract Interferon regulatory factors (IRFs) play a key role in many aspects of immune response, and IRF1, IRF3, and IRF7 are positive regulators of IFN induction in mammals. However, IRF3, as the most critical regulatory factor in mammals, is natur
Externí odkaz:
https://doaj.org/article/38cdd83a4b124efab35fe040dd3f00bc
Autor:
Jie Wang, Xiangyu Yu, Shurui Zhao, Nian Zhang, Zhenyu Lin, Zhaofei Wang, Jingjiao Ma, Yaxian Yan, Jianhe Sun, Yuqiang Cheng
Publikováno v:
Poultry Science, Vol 101, Iss 12, Pp 102147- (2022)
ABSTRACT: The mammalian-derived MDCK cells are the most widely used for avian virus vaccine production at present. The use of heterologous cell systems for avian virus preparation may cause security risks. An avian cell line is available for avian vi
Externí odkaz:
https://doaj.org/article/f804063405cc4bc7a3269ea2ed56b763
Autor:
Yumin Zhang, Guoqing Zhao, Yangjing Xiong, Feiyu Li, Yifan Chen, Yuqiang Cheng, Jingjiao Ma, Henan Wang, Yaxian Yan, Zhaofei Wang, Jianhe Sun
Publikováno v:
Veterinary Sciences, Vol 10, Iss 6, p 383 (2023)
Streptococcus suis is a significant zoonotic pathogen that is a great threat not only to the swine industry but also to human health, causing arthritis, meningitis, and even streptococcal toxic shock-like syndrome. Owing to its many serotypes and hig
Externí odkaz:
https://doaj.org/article/c799d84047154fd7b7239c1e57cb2a21
Autor:
Feiyu Fu, Zhenyu Lin, Yanlin Li, Jie Wang, Yawen Li, Pengcheng Liu, Zhaofei Wang, Jingjiao Ma, Yaxian Yan, Jianhe Sun, Yuqiang Cheng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stimulator of the interferon gene (STING) is involved in mammalian antiviral innate immunity as an interferon (IFN) activator. However, there is still a lack of clarity regarding the molecular characterization of goose STING (GoSTING) and its role in
Externí odkaz:
https://doaj.org/article/0ed5b7039aa24ad2901b6a477612f979
Autor:
Jie Wang, Zhenyu Lin, Qiuju Liu, Feiyu Fu, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Yuqiang Cheng, Jianhe Sun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention. In this study, t
Externí odkaz:
https://doaj.org/article/d7b8cae483ab4b0d9248bc76d7c39ea8