Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Yawen Chiang"'
Autor:
Dennis M. Marcus, Carl C. Awh, Fan Tang, Peter A. Campochiaro, Joshua Horvath, Katie F. Maass, Vladimir Bantseev, Natasha Singh, Jason S. Ehrlich, Carl D. Regillo, William D. Hanley, Yawen Chiang, Anthony P. Adamis, Giulio Barteselli, Signe Erickson
Publikováno v:
Ophthalmology. 126:1141-1154
Purpose To evaluate the safety and efficacy of the Port Delivery System with ranibizumab (PDS) for neovascular age-related macular degeneration (nAMD) treatment. Design Phase 2, multicenter, randomized, active treatment–controlled clinical trial. P
Autor:
Peter A, Campochiaro, Dennis M, Marcus, Carl C, Awh, Carl, Regillo, Anthony P, Adamis, Vladimir, Bantseev, Yawen, Chiang, Jason S, Ehrlich, Signe, Erickson, William D, Hanley, Joshua, Horvath, Katie F, Maass, Natasha, Singh, Fan, Tang, Giulio, Barteselli
Publikováno v:
Ophthalmology. 126(8)
To evaluate the safety and efficacy of the Port Delivery System with ranibizumab (PDS) for neovascular age-related macular degeneration (nAMD) treatment.Phase 2, multicenter, randomized, active treatment-controlled clinical trial.Patients diagnosed w
Autor:
Melissa Diagana, Ying Zhang, Augustine Lin, Nicole Belmar, Melinda Meier, Kimvan Tran, Florence Boissiere, Dirk Brockstedt, Yawen Chiang, Adrienne Yang
Publikováno v:
Molecular Therapy. 6(5):627-636
Gene therapy for cancer using suicide genes such as the herpes simplex virus thymidine kinase gene (HSVtk) has been explored extensively in preclinical and clinical studies. We have improved the use of HSVtk by combining it with two cytokine genes en
Autor:
Ira Pastan, Michael M. Gottesman, Kenneth H. Cowan, David Venzon, Susan F. Leitman, Barry Goldspiel, Stephanie Sellers, Yawen Chiang, Charles Carter, Brian Sorrentino, Cathy Chow, Hui Huang, Cynthia E. Dunbar, Georgie Cusack, Andrea Abati, Elizabeth J. Read, Jeffrey A. Moscow, Jo Anne Zujewski, Kenneth Hines
Publikováno v:
Blood. 94:52-61
To determine whether the multidrug resistance gene MDR1could act as a selectable marker in human subjects, we studied engraftment of peripheral blood progenitor cells (PBPCs) transduced with either MDR1 or the bacterial NeoR gene in six breast cancer
Autor:
Christophe Ferrand, Patrick Hervé, Yawen Chiang, Jean-Marie Certoux, Craig W. Reynolds, Jean-Yves Cahn, Pierre Tiberghien, Emmanuel Contassot, William Jacob
Publikováno v:
Human Gene Therapy. 9:73-80
We have demonstrated in previous studies that retrovirus-mediated transfer of the herpes simplex thymidine kinase (HS-tk) and neomycin phosphotransferase (neo) genes in CD3/IL-2 stimulated primary T lymphocytes followed by G418 selection resulted in
Autor:
E. M. Oshiro, Linda M. Muul, E. Otto, Edward H. Oldfield, Yawen Chiang, R. M. Blaese, Zvi Ram, J. J. Viola, Zhifeng Long, Hetty L. DeVroom, Kenneth W. Culver, G. J. Mcgarrity, David A. Katz
Publikováno v:
Nature Medicine. 3:1354-1361
Intratumoral implantation of murine cells modified to produce retroviral vectors containing the herpes simplex virus-thymidine kinase (HSV-TK) gene induces regression of experimental brain tumors in rodents after ganciclovir (GCV) administration. We
Autor:
Kathleen F. Pirollo, Gloria L. Murphy, Yawen Chiang, Howard H. Sussman, Esther H. Chang, Zhengmei Hao, Yng-Ju Jang, Willard E. Fee, Antonina Rait, Patricia Ryan
Publikováno v:
Archives of Otolaryngology - Head and Neck Surgery. 123:507-512
Background: A significant number of squamous cell carcinomas of the head and neck (SCCHN) resist radiation treatment, the most common form of adjuvant therapy for this disease. The presence of a mutant form of the tumor suppressor gene p53 has been c
Autor:
Jean-Yves Cahn, Patrick Hervé, Bruno Lioure, Evelyne Racadot, Yawen Chiang, Pierre Bordigoni, Craig W. Reynolds, Elaine Gluckman, Noel Milpied, Eric Deconinck, Pierre Tiberghien, Will Jacob, Steve Marcus, Dan L. Longo, Annie Brion
Publikováno v:
Human Gene Therapy. 8:615-624
Allogeneic bone marrow transplantation (BMT) is associated with a severe complication; graft-versus-host disease (GvHD). While effectively preventing GvHD, ex-vivo T lymphocyte marrow depletion unfortunately increases graft rejection and reduces the
Publikováno v:
Somatic Cell and Molecular Genetics. 21:205-214
A set of chimeric envelope proteins between amphotropic and xenotropic murine leukemia retroviruses (MuLV), two closely related members in the MuLV family, were constructed. The purpose was to examine the regions that could be successfully exchanged
Publikováno v:
Human Gene Therapy. 6:55-85
Leptomeningeal carcinomatosis occurs in 5% to 20% of all cancer patients (9, 18, 22). Among the adult population, most cases of leptomeningeal carcinomatosis are due to breast or lung carcinomas. Over recent years the incidence of leptomeningeal carc