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Personal Security and Safety In Academic Libraries: A Case Study of the Kwame Nkrumah University of Science and Technology Library, Kumasi, Ghana

Autor: Yaw Senyah, Richard Bruce Lamptey

Publikováno v: Library & Archival Security. 24:83-102

This case study aims at a critical examination of the security risks to which staff of Kwame Nkrumah University of Science and Technology (KNUST) Library are exposed and measures put in place to deal with them. It also assesses the personal safety me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25dcec754b38940424ba695e8a136240
https://doi.org/10.1080/01960075.2011.604642

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Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist

Autor: Salituro Francesco G, Vicki L. Taylor, Barry W. Siegel, Bruce M. Baron, John H. Kehne, Yaw Senyah, Harrison Boyd L, H.Steven White, Paul L.M. Van Giersbergen, Phillip L. Nyce, Christopher J. Schmidt, Michael Murawsky, Gina M. Fadayel, Timothy C. McCloskey

Publikováno v: European Journal of Pharmacology. 323:181-192

MDL 105,519, ( E )-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1 H -indole-2-carboxylic acid, is a potent and selective inhibitor of [ 3 H]glycine binding to the NMDA receptor. MDL 105,519 inhibits NMDA ( N -methyl- d -aspartate)-dependent responses i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea8d87937b04bbd1e28a1154c486add
https://doi.org/10.1016/s0014-2999(97)00045-9

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ChemInform Abstract: 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as Selective Antagonists of Strychnine-Induced Convulsions and Potential Antispastic Agents

Autor: M. A. Staeger, Yaw Senyah, Miller Francis P, Timothy C. McCloskey, Ann Marie L. Ogden, Herbert J. Ketteler, John M. Kane, John H. Kehne, Dalton Christopher R, P. A. Chmielewski, Mark W. Dudley, Jerry A. Miller

Publikováno v: ChemInform. 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::039f5be56904ab180300c3cb0fd3a805
https://doi.org/10.1002/chin.199417156

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AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents

Autor: Michal Arad, Jeanne Stemmelin, Caroline Cohen, Yaw Senyah, Beth Borowsky, Philippe Pichat, Stevens Rachel, Amaya De Levie, Segev Barak, Odessa Giardino, Guy Griebel, Geoffrey B. Varty, Robert E. Featherstone, Ina Weiner, Mark D. Black, Nancy Rogacki

Publikováno v: Psychopharmacology. 215(1)

The psychotomimetic effects of cannabis are believed to be mediated via cannabinoid CB1 receptors. Furthermore, studies have implicated CB1 receptors in the pathophysiology of schizophrenia.These studies investigated the effects of the CB1 receptor a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff538435e5f56b49a1bf449b7c736fda
https://pubmed.ncbi.nlm.nih.gov/21181124

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MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord

Autor: John M. Kane, Yaw Senyah, Timothy C. McCloskey, Herbert J. Ketteler, John H. Kehne, Michael G. Palfreyman

Publikováno v: Neuroscience letters. 147(1)

Disrupted glycinergic inhibition in the brainstem and spinal cord may contribute to some of the alterations in reflex control seen in patients with spastic disorders. MDL 27,531, which acts functionally like a glycine agonist in its capacity to selec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6eae67bb7328631ad8f89bf4f6a49e
https://pubmed.ncbi.nlm.nih.gov/1480315

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MDL 27,531 selectively reverses strychnine-induced seizures in mice

Autor: Ann Marie Ogden, John H. Kehne, John M. Kane, Stephen F. Chaney, Donald L. Braun, Miller Francis P, Michael G. Palfreyman, Mark W. Dudley, Abdulmuniem Abdallah, Herbert J. Ketteler, Yaw Senyah

1. Strychnine-sensitive glycine receptors are primarily localized in the brainstem and spinal cord where they are the major mediators of postsynaptic inhibition. A compound which acts functionally like a glycine receptor agonist would be potentially

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a2f43190754ee7179cb6781f0673df
https://europepmc.org/articles/PMC1907658/