Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yavuz S. Dagdas"'
Publikováno v:
eLife, Vol 4 (2015)
Telomerase synthesizes chromosome-capping telomeric repeats using an active site in telomerase reverse transcriptase (TERT) and an integral RNA subunit template. The fundamental question of whether human telomerase catalytic activity requires coopera
Externí odkaz:
https://doaj.org/article/6c093ebd41384aa2baf44d83260ca63a
Autor:
Patrick G. Holder, Shion A. Lim, Christine S. Huang, Preeti Sharma, Yavuz S. Dagdas, Beyza Bulutoglu, Jonathan T. Sockolosky
Publikováno v:
Advanced Drug Delivery Reviews. 182:114112
Cytokines are a class of potent immunoregulatory proteins that are secreted in response to various stimuli and act locally to regulate many aspects of human physiology and disease. Cytokines play important roles in cancer initiation, progression, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76b66258b059444af35960b2bb329ad
https://doi.org/10.1016/j.addr.2022.114112
https://doi.org/10.1016/j.addr.2022.114112
Autor:
Samuel H. Sternberg, Benjamin P. Kleinstiver, Ahmet Yildiz, J. Keith Joung, Jennifer A. Doudna, Janice S. Chen, Lucas B. Harrington, Yavuz S. Dagdas, Alexander A. Sousa, Moira M. Welch
Publikováno v:
Nature, vol 550, iss 7676
Nature
Nature
The RNA-guided CRISPR-Cas9 nuclease from Streptococcus pyogenes (SpCas9) has been widely repurposed for genome editing. High-fidelity (SpCas9-HF1) and enhanced specificity (eSpCas9(1.1)) variants exhibit substantially reduced off-target cleavage in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7591187f7d0e1cd6ee825c8ba6c2d5
https://doi.org/10.1038/nature24268
https://doi.org/10.1038/nature24268
Autor:
Yavuz S. Dagdas, Jennifer A. Doudna, J. Keith Joung, Benjamin P. Kleinstiver, Moira M. Welch, Ahmet Yildiz, Samuel H. Sternberg, Janice S. Chen, Lucas B. Harrington
The RNA-guided CRISPR-Cas9 nuclease from Streptococcus pyogenes (SpCas9) has been widely repurposed for genome editing1-4. High-fidelity (SpCas9-HF1) and enhanced specificity (eSpCas9(1.1)) variants exhibit substantially reduced off-target cleavage i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ce32ae662003fd7d0b44f688c09069
Publikováno v:
Science Advances
Science advances, vol 3, iss 8
Science advances, vol 3, iss 8
A conformational checkpoint of Cas9 enables on-target cleavage while blocking access to the active state at off-target sites.
The Cas9 endonuclease is widely used for genome engineering applications by programming its single-guide RNA, and ongoi
The Cas9 endonuclease is widely used for genome engineering applications by programming its single-guide RNA, and ongoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1a12df94f7b397c9a297e260be93d9
https://doi.org/10.1101/122242
https://doi.org/10.1101/122242
Publikováno v:
Wu, RA; Dagdas, YS; Yilmaz, ST; Yildiz, A; & Collins, K. (2015). Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes. eLife, 4(OCTOBER2015). doi: 10.7554/eLife.08363. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/5gq2620h
eLife, vol 4, iss OCTOBER2015
eLife
eLife, Vol 4 (2015)
eLife, vol 4, iss OCTOBER2015
eLife
eLife, Vol 4 (2015)
Telomerase synthesizes chromosome-capping telomeric repeats using an active site in telomerase reverse transcriptase (TERT) and an integral RNA subunit template. The fundamental question of whether human telomerase catalytic activity requires coopera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76c3ed60adba4221c96d9f9a625f073
http://www.escholarship.org/uc/item/5gq2620h
http://www.escholarship.org/uc/item/5gq2620h
Publikováno v:
Biophysical Journal. 112:71a
Cas9 is an RNA-guided endonuclease that cleaves double-stranded DNA using two conserved nuclease domains, RuvC and HNH, as part of CRISPR-Cas bacterial adaptive immune systems. Together with single-guide RNAs, Cas9 is also widely utilized as a progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b210f5e36387e23da6534c012a8504
https://doi.org/10.1016/j.bpj.2016.11.429
https://doi.org/10.1016/j.bpj.2016.11.429
Autor:
Yavuz S. Dagdas, Gozde Uzunalli, Ayse B. Tekinay, Zeliha Soran, Kamil Bilgihan, Ahmet Hondur, Turan S. Erkal, Bahri Aydin, Mustafa O. Guler, Erdem Dinç
Publikováno v:
Acta Biomaterialia
Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental for vision. Development of therapeutic methods to enhance corneal regeneration is essential for treatment of these defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371f35c42549dfc568bba975be63a2c9
https://avesis.gazi.edu.tr/publication/details/3e604339-6fe3-4547-ba14-a3a8384fc47b/oai
https://avesis.gazi.edu.tr/publication/details/3e604339-6fe3-4547-ba14-a3a8384fc47b/oai
Publikováno v:
Soft Matter
Molecular self-assembly is a powerful technique for developing novel nanostructures by using noncovalent interactions such as hydrogen bonding, hydrophobic, electrostatic, metal-ligand, p-p and van der Waals interactions. These interactions are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c4bbfb4de8b690c8009b7a49638dfa
https://aperta.ulakbim.gov.tr/record/21059
https://aperta.ulakbim.gov.tr/record/21059