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Identification of Five Chronic Obstructive Pulmonary Disease Subgroups with Different Prognoses in the ECLIPSE Cohort Using Cluster Analysis

Publikováno v: Annals of the American Thoracic Society, 12(3), 303-312. American Thoracic Society
Rennard, S I, Tal-Singer, R M, Silverman, E K, Miller, B E, Bakke, P, Celli, B R, Calverley, P M A, Coxson, H O, Crim, C, Edwards, L D, Lomas, D A, Macnee, W, Wouters, E F M, Yates, J C, Agusti, A & ECLIPSE Investigators 2015, ' Identification of Five Chronic Obstructive Pulmonary Disease Subgroups with Different Prognoses in the ECLIPSE Cohort Using Cluster Analysis ', American Thoracic Society. Annals
, vol. 12, no. 3, pp. 303-312 . https://doi.org/10.1513/AnnalsATS.201403-125OC

RATIONALE: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that likely includes clinically relevant subgroups. OBJECTIVES: To identify subgroups of COPD in ECLIPSE (Evaluation of COPD Longitudinally to Identify Predictive Surr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46b8047a809806b2a37d24edeed0ab2
https://cris.maastrichtuniversity.nl/en/publications/eaafa7a0-baa8-4b9b-bb0d-d21cf11e9f10

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Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

Publikováno v: Thorax, 69(8), 718-723. BMJ Publishing Group
Williams, M C, Murchison, J T, Edwards, L D, Agusti, A, Bakke, P, Calverley, P M A, Celli, B, Coxson, H O, Crim, C, Lomas, D A, Miller, B E, Rennard, S, Silverman, E K, Tal-Singer, R, Vestbo, J, Wouters, E, Yates, J C, Van Beek, E J R, Newby, D E, MacNee, W & Evaluation, C L 2014, ' Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality ', Thorax, vol. 69, no. 8, pp. 718-723 . https://doi.org/10.1136/thoraxjnl-2012-203151

Background Coronary artery calcification is pathognomonic of coronary artery disease (CAD). Whether CAD in patients with COPD is linked to lung function, functional capacity and/or clinically relevant outcomes is unknown. The objective was to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa756aaaac81cc3c336da7a5cea704e
https://cris.maastrichtuniversity.nl/en/publications/31921aa5-fba7-4110-9649-54e73d989f23

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Should We View Chronic Obstructive Pulmonary Disease Differently after ECLIPSE? A Clinical Perspective from the Study Team

Autor: Vestbo, J., Agusti, A., Wouters, E.F.M., Bakke, P., Calverley, P.M.A., Celli, B., Coxson, H., Crim, C., Edwards, L.D., Locantore, N., Lomas, D.A., MacNee, W., Miller, B., Rennard, S.I., Silverman, E.K., Yates, J.C., Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Study Investigators, the, Tal-Singer, R.

Publikováno v: American Journal of Respiratory and Critical Care Medicine, 189(9), 1022-1030. American Thoracic Society
Vestbo, J, Agusti, A, Wouters, E F M, Bakke, P, Calverley, P M A, Celli, B, Coxson, H, Crim, C, Edwards, L D, Locantore, N, Lomas, D A, MacNee, W, Miller, B, Rennard, S I, Silverman, E K, Yates, J C, Tal-Singer, R & Evaluation, C L I 2014, ' Should We View Chronic Obstructive Pulmonary Disease Differently after ECLIPSE? A Clinical Perspective from the Study Team ', American Journal of Respiratory and Critical Care Medicine, vol. 189, no. 9, pp. 1022-1030 . https://doi.org/10.1164/rccm.201311-2006PP

Rationale: Chronic obstructive pulmonary disease (COPD) seems to be a heterogeneous disease with a variable course. Objectives: We wished to characterize the heterogeneity and variability of COPD longitudinally. Methods: In the Evaluation of COPD Lon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5205af5279c160c2db184daba3eec7
https://cris.maastrichtuniversity.nl/en/publications/85678e3b-8879-45a1-99fe-8568f8b5406b

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Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort

Autor: Janssen, D.J.A., Mullerova, H., Agusti, A., Yates, J.C., Tal-Singer, R., Rennard, S.I., Vestbo, J., Eclipse Investigators, the, Wouters, E.F.M.

Publikováno v: Janssen, D J A, Mullerova, H, Agusti, A, Yates, J C, Tal-Singer, R, Rennard, S I, Vestbo, J, Wouters, E F M & Eclipse, I 2014, ' Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort ', Respiratory Medicine, vol. 108, no. 11, pp. 1647-1654 . https://doi.org/10.1016/j.rmed.2014.07.013
Respiratory Medicine, 108(11), 1647-1654. Elsevier Saunders

Background: Depression is highly prevalent among patients with Chronic Obstructive Pulmonary Disease (COPD). The relationship of depression with systemic inflammation in COPD remains unknown. The objective of this observational study was to compare d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4b941a9efdee861addd2218d8e67d6
https://pubmed.ncbi.nlm.nih.gov/25135745

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Common Genetic Variants Associated with Resting Oxygenation in Chronic Obstructive Pulmonary Disease

Publikováno v: American Journal of Respiratory Cell and Molecular Biology, 51(5), 678-687. American Thoracic Society
McDonald, M-L N, Cho, M H, Sørheim, I-C, Lutz, S M, Castaldi, P J, Lomas, D A, Coxson, H O, Edwards, L D, MacNee, W, Vestbo, J, Yates, J C, Agusti, A, Calverley, P M A, Celli, B, Crim, C, Rennard, S I, Wouters, E F M, Bakke, P, Tal-Singer, R, Miller, B E, Gulsvik, A, Casaburi, R, Wells, J M, Regan, E A, Make, B J, Hokanson, J E, Lange, C, Crapo, J D, Beaty, T H, Silverman, E K, Hersh, C P, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints and COPDGene Investigators & Mattheisen, M 2014, ' Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease ' American Journal of Respiratory Cell and Molecular Biology (Online), vol. 51, no. 5, pp. 678-87 . https://doi.org/10.1165/rcmb.2014-0135OC
American journal of respiratory cell and molecular biology, vol 51, iss 5

Hypoxemia is a major complication of chronic obstructive pulmonary disease (COPD) that correlates with disease prognosis. Identifying genetic variants associated with oxygenation may provide clues for deciphering the heterogeneity in prognosis among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6b85c0cf42a2fe921db7675dd59c4d
https://cris.maastrichtuniversity.nl/en/publications/4927b6a8-a84b-4d93-9586-839cf22b3a20

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