Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Yate Ching Yuan"'
Autor:
Margarita Gutova, Jonathan C. Hibbard, Eric Ma, Heini M. Natri, Vikram Adhikarla, Nyam-Osor Chimge, Runxiang Qiu, Cu Nguyen, Elizabeth Melendez, Brenda Aguilar, Renate Starr, Holly Yin, Russel C. Rockne, Masaya Ono, Nicholas E. Banovich, Yate-Ching Yuan, Christine E. Brown, Michael Kahn
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite aggressive standard-of-care therapy, including surgery, radiation, and chemotherapy, glioblastoma recurrence is almost inevitable and uniformly lethal. Activation of glioma-intrinsic Wnt/β-catenin signaling is associated with a p
Externí odkaz:
https://doaj.org/article/46059b87db0348ce905d3e52ef396589
Autor:
Ajay Goel, Yuya Yoshimoto, Yate-Ching Yuan, Takashi Ogata, Hiroyuki Katoh, Yoshiyuki Suzuki, Fumiaki Takahashi, Takashi Oshima, Daisaku Yoshida, Alessandra Nardin, Michael Fehlings, Kosaku Mimura, Phuong H D Nguyen, Souvick Roy, Hassen Kared, Shotaro Nakajima, Hisashi Sato, Nozomu Machida, Takanobu Yamada, Yohei Watanabe, Tomoaki Tamaki, Hirohito Fujikawa, Yasuhiro Inokuchi, Suguru Hayase, Hiroyuki Hanayama, Zenichiro Saze, Koji Kono
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Tumor-associated antigen (TAA)-specific CD8(+) T cells are essential for nivolumab therapy, and irradiation has been reported to have the potential to generate and activate TAA-specific CD8(+) T cells. However, mechanistic insights of T-ce
Externí odkaz:
https://doaj.org/article/4ebaa04ef7ec4c62ba91fa761c93160d
Autor:
Jabril R. Johnson, Rachel N. Martini, Yate-Ching Yuan, Leanne Woods-Burnham, Mya Walker, Greisha L. Ortiz-Hernandez, Firas Kobeissy, Dorothy Galloway, Amani Gaddy, Chidinma Oguejiofor, Blake Allen, Deyana Lewis, Melissa B. Davis, K. Sean Kimbro, Clayton C. Yates, Adam B. Murphy, Rick A. Kittles
Publikováno v:
Biology, Vol 13, Iss 5, p 346 (2024)
Vitamin D3 is a steroid hormone that confers anti-tumorigenic properties in prostate cells. Serum vitamin D3 deficiency has been associated with advanced prostate cancer (PCa), particularly affecting African American (AA) men. Therefore, elucidating
Externí odkaz:
https://doaj.org/article/b5fd757d1f144835a1aa0d5550f53b77
Autor:
Linlin Guo, Atish Mohanty, Sharad Singhal, Saumya Srivastava, Arin Nam, Charles Warden, Sravani Ramisetty, Yate-Ching Yuan, Hyejin Cho, Xiwei Wu, Aimin Li, Manik Vohra, Srinivas Vinod Saladi, Deric Wheeler, Leonidas Arvanitis, Erminia Massarelli, Prakash Kulkarni, Yiming Zeng, Ravi Salgia
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107302- (2023)
Summary: This study investigates the role of integrin β4 (ITGB4) and stemness-associated factor SOX2 in platinum resistance in lung squamous cell carcinoma (LUSC). The expression of SOX2 and ITGB4 is found to be high in all LUSC subtypes, but the im
Externí odkaz:
https://doaj.org/article/9962e7214592483093812b263a3e559e
Autor:
Zhen Han, Xiwei Wu, Hanjun Qin, Yate-Ching Yuan, Daniel Schmolze, Chingyu Su, Jasmine Zain, Lilach Moyal, Emmilia Hodak, James F. Sanchez, Peter P. Lee, Mingye Feng, Steven T. Rosen, Christiane Querfeld
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Cutaneous T cell lymphoma (CTCL) is a disfiguring and incurable disease characterized by skin-homing malignant T cells surrounded by immune cells that promote CTCL growth through an immunosuppressive tumor microenvironment (TME). Preliminary data fro
Externí odkaz:
https://doaj.org/article/aea90ab340bd4aec9702c4b9ba05a095
Autor:
Zhiqiang Wang, Chunxiao Zhang, Charles David Warden, Zheng Liu, Yate-Ching Yuan, Chao Guo, Charles Wang, Jinhui Wang, Xiwei Wu, Richard Ermel, Steven L. Vonderfecht, Xiuli Wang, Christine Brown, Stephen Forman, Yaling Yang, M. James You, WenYong Chen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Studies employing serial bone marrow transplantation in mice show that Sirt1 knockout improves quiescence maintenance and function of aging hematopoietic stem cells. Sirt1 loss also prevents the development of age-dependent B/myeloid mixed phenotype
Externí odkaz:
https://doaj.org/article/9d0e1dc32e3944ccbb5ec887342c8d2e
Autor:
Lu Yang, Anthony K. N. Chan, Kazuya Miyashita, Christopher D. Delaney, Xi Wang, Hongzhi Li, Sheela Pangeni Pokharel, Sandra Li, Mingli Li, Xiaobao Xu, Wei Lu, Qiao Liu, Nicole Mattson, Kevin Yining Chen, Jinhui Wang, Yate-Ching Yuan, David Horne, Steven T. Rosen, Yadira Soto-Feliciano, Zhaohui Feng, Takayuki Hoshii, Gang Xiao, Markus Müschen, Jianjun Chen, Scott A. Armstrong, Chun-Wei Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Identifying functional domains and genetic regulatory mechanisms is essential for developing new therapies. Here the authors present sc-Tiling, single-cell high-density CRISPR tiling screening for functional domain characterization.
Externí odkaz:
https://doaj.org/article/ddb7b59f991343969e3fce23606cbf5c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/003e6c7da8744bfcb1651f069de2de90
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundNaturally occurring dietary botanicals offer time-tested safety and anti-cancer efficacy, and a combination of certain compounds has shown to overcome the elusive chemotherapeutic resistance, which is of great significance for improving the
Externí odkaz:
https://doaj.org/article/7b173b421fe1448c8e29f343d0414705
Autor:
Mohamed Hammad, Yvonne R. Cornejo, Jennifer Batalla-Covello, Asma Abdul Majid, Connor Burke, Zheng Liu, Yate-Ching Yuan, Min Li, Thanh H. Dellinger, Jianming Lu, Nanhai G. Chen, Yuman Fong, Karen S. Aboody, Rachael Mooney
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 326-334 (2020)
Oncolytic virotherapy represents a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance, which reduces viral delivery to
Externí odkaz:
https://doaj.org/article/a51f6d5caa604ac6b003ff4ce600670f