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pro vyhledávání: '"Yatao Bao"'
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Genetic factors play an important role in the pathogenesis of systemic lupus erythematosus (SLE), and abnormal Toll-like receptor (TLR) signaling pathways are closely related to the onset of SLE. In previous studies, we found that the mutant somatic
Externí odkaz:
https://doaj.org/article/81ec031d4722489da9b571c286344ee8
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
A variant of somatic nuclear autoantigenic sperm protein (sNASP) was identified from the murine lupus susceptibility locus Sle2c1 by whole exome sequencing (WES). Previous studies have shown that mutant sNASP could synergize with the Faslpr mutation
Externí odkaz:
https://doaj.org/article/8c0538a7dd824bcfa2a7450dac039143
Publikováno v:
Lupus. 31(3)
Background The genetic factor is a great driver of systemic lupus erythematosus. A Skint6 W168X allele was previously identified in the murine lupus susceptibility rec1d1 sublocus. The purpose of this study is to investigate the pathogenic role and m