Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yat Hei Leung"'
Autor:
Abel Oppong, Yat Hei Leung, Anindya Ghosh, Marie-Line Peyot, Marilène Paquet, Carlos Morales, Hugh J. Clarke, Fahd Al-Mulla, Alexandre Boyer, S. R. Murthy Madiraju, Derek Boerboom, Cristian O'Flaherty, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102063- (2024)
Objectives: Obesity, diabetes and high-calorie diets are associated with defective sperm function and lowered male fertility. Mature spermatozoa primarily use fructose and glucose, and glucose and glycerol metabolism are important for sperm function.
Externí odkaz:
https://doaj.org/article/315c683a57974e74b09d44fa08f9ae3d
Autor:
Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Isabelle Chenier, Yat Hei Leung, Anindya Ghosh, Abel Oppong, Elite Possik, Yves Mugabo, Rasheed Ahmad, Robert Sladek, S.R. Murthy Madiraju, Fahd Al-Mulla, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101609- (2022)
Objective: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a “glycerol shunt”, a metabolic pathway that we identified recently in mammalian cells. We have investigated the role o
Externí odkaz:
https://doaj.org/article/ef4e4aa106094673b2a836cb280c8599
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 42 (2017)
Many drugs can cause unexpected muscle disorders, often necessitating the cessation of an effective medication. Inhibition of monocarboxylate transporters (MCTs) may potentially lead to perturbation of l-lactic acid homeostasis and muscular toxicity.
Externí odkaz:
https://doaj.org/article/9c75936f87a044dbbdff6253c7580929
Autor:
Anindya Ghosh, Marie-Line Peyot, Yat Hei Leung, François Ravenelle, S R Murthy Madiraju, Marc Prentki
Publikováno v:
European Journal of Pharmacology. 944:175589
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70a338cbda0ebbd68aa1628cd22d485
https://doi.org/10.1016/j.ejphar.2023.175589
https://doi.org/10.1016/j.ejphar.2023.175589
Autor:
Yat Hei Leung, Rasheed Ahmad, Fahd Al-Mulla, Sardar Sindhu, Marc Prentki, Hossein Arefanian, S.R. Murthy Madiraju
Publikováno v:
Obesity Reviews
Summary Sphingolipids, in particular ceramides, play vital role in pathophysiological processes linked to metabolic syndrome, with implications in the development of insulin resistance, pancreatic ß‐cell dysfunction, type 2 diabetes, atheroscleros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0b215a8befa6f85cbec12cd240b5b2
https://doi.org/10.1111/obr.13248
https://doi.org/10.1111/obr.13248
Publikováno v:
Current Pharmaceutical Biotechnology. 18:1141-1150
Background Drug-induced myopathy is a serious side effect that often requires removal of a medication from a drug regimen. For most drugs, the underlying mechanism of drug-induced myopathy remains unclear. Monocarboxylate transporters (MCTs) mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a98c7a64a3d3893322a91a85e3ad5f
https://doi.org/10.2174/1389201019666180308091504
https://doi.org/10.2174/1389201019666180308091504
Publikováno v:
Pharmaceutics; Volume 9; Issue 4; Pages: 42
Pharmaceutics
Pharmaceutics, Vol 9, Iss 4, p 42 (2017)
Pharmaceutics
Pharmaceutics, Vol 9, Iss 4, p 42 (2017)
Many drugs can cause unexpected muscle disorders, often necessitating the cessation of an effective medication. Inhibition of monocarboxylate transporters (MCTs) may potentially lead to perturbation of l-lactic acid homeostasis and muscular toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061228cdf3667d311e596446d246a8b8
Autor:
Dylan T. McLaughlin, Parsram Ramrup, Thi Phuong Thao Nguyen, Yat Hei Leung, Leinjo Mengnjo, Louis A. Cuccia, Simon Woo, Cheng Bian, Elliot Goodfellow
Publikováno v:
Crystal Growth & Design. 14:1067-1076
Viedma ripening is the attrition-induced spontaneous chiral amplification of a conglomerate crystal mixture. To demonstrate the general nature of this deracemization process, we have extended attrition-enhanced chiral amplification to 10 achiral orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40efdeb736e24b845c69f58300fba16c
https://doi.org/10.1021/cg401577m
https://doi.org/10.1021/cg401577m
Autor:
Jennifer Lu, Yat Hei Leung, Fleur Gaudette, Liliam Gabriela Guilarte Moya, Jacques Turgeon, Veronique Michaud
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 352(3)
The organic anion transporting polypeptide 1A2 (OATP1A2), a membrane drug transporter expressed on important organs (such as the brain, kidney, and intestine) may be a key element in the disposition of drugs. Previous studies demonstrated that it cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315a902114bbcfd3519f4ae04d39aaf5
https://pubmed.ncbi.nlm.nih.gov/25563901
https://pubmed.ncbi.nlm.nih.gov/25563901
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ca9c7d864a2cfdb7426406f82bf0351
https://doi.org/10.1096/fasebj.27.1_supplement.674.2
https://doi.org/10.1096/fasebj.27.1_supplement.674.2