Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasuyuki Tsutsumishita"'
Publikováno v:
Cancer Science. 100:189-194
Miriplatin is a lipophilic platinum complex which contains myristates as leaving groups and diaminocyclohexane as a carrier ligand. In order to examine in vivo the antitumor activities of miriplatin suspended in an oily lymphographic agent (Lipiodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38832aafedfa5f4f3867cd97b66400d0
https://doi.org/10.1111/j.1349-7006.2008.01010.x
https://doi.org/10.1111/j.1349-7006.2008.01010.x
Autor:
Fumio Nishikaku, Toshihiro Noguchi, Akemi Baba, Yasuyuki Tsutsumishita, Mitsuharu Hanada, Nobuyoshi Chiba, Takashi Yamaoka
Publikováno v:
Cancer Chemotherapy and Pharmacology
Background Miriplatin (formerly SM-11355), a novel lipophilic platinum complex developed to treat hepatocellular carcinoma, is administered into the hepatic artery using an oily lymphographic agent (Lipiodol Ultra-Fluide®) as a carrier. We clarified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c995d9a0b4aad19dfa5c32756b7b1f1
https://doi.org/10.1007/s00280-008-0895-3
https://doi.org/10.1007/s00280-008-0895-3
Autor:
Keiko Kitajima, Shiroh Futaki, Noriko Nakamura, Mari Ueda, Yoshihisa Takaishi, Yasuyuki Tsutsumishita, Mineo Niwa
Publikováno v:
Biochemical and Biophysical Research Communications. 239:367-371
Benzoquinones inhibited the production of NO induced by LPS and γ-IFN in C6 glia cells. The mechanistic studies showed that benzoquinones inhibited the expression of iNOS mRNA through inactivation of NF κ B. Benzoquinones may be a useful candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14261377cf2d33ce58330aa5c173fe42
https://doi.org/10.1006/bbrc.1997.7437
https://doi.org/10.1006/bbrc.1997.7437
Autor:
Kenji Katoh, Takaaki Ikata, Mineo Niwa, Yasuyuki Tsutsumishita, Shinsuke Katoh, Yoshitaka Hamada, Kenji Fukuzawa
Publikováno v:
Neuroscience Letters. 203:97-100
This study was undertaken to examine the effect of transforming growth factor-beta 1 (TGF-beta 1) administered into the subarachnoid space after spinal cord injury (SCI) on the increased production of inducible-nitric oxide synthase (i-NOS) in the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f99f5719b450eb46750c7742804280
https://doi.org/10.1016/0304-3940(95)12271-0
https://doi.org/10.1016/0304-3940(95)12271-0
Autor:
Yasuyuki Tsutsumishita, Mineo Niwa, Tomoaki Onda, Shiroh Futaki, Hitoshi Endou, Kaname Okada, Michio Takeda
Publikováno v:
Biochemical and Biophysical Research Communications. 242:310-312
The purpose of this study was to elucidate the involvement of H2O2 production in cisplatin-induced nephrotoxicity. The S3 cells were more sensitive than OMCT cells in cell viability and H2O2 production during cisplatin treatment. The cytotoxicity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f2793c205b3036a5b9dc45ba906b30
https://doi.org/10.1006/bbrc.1997.7962
https://doi.org/10.1006/bbrc.1997.7962
Autor:
Mineo Niwa, Yasuyuki Tsutsumishita, Shiroh Futaki, Yumiko Kawai, Junko Miyoshi, Tomoaki Onda, Hideo Takahara
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1374-1376
The nucleotide sequences of inducible nitric oxide synthase (iNOS) cDNA in rat kidney, lung, and uterus were determined. The amino acid sequences of iNOSs in various organs were highly homologous, and the important regions for the enzyme activity hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603140c946ca01586f78d31c1b3438d4
https://doi.org/10.1248/bpb.19.1374
https://doi.org/10.1248/bpb.19.1374
Autor:
Yumiko Kawai, Noriko Nakamura, Mineo Niwa, Shiroh Futaki, Yasuyuki Tsutsumishita, Yoshihisa Takaishi, Hideo Takahara, Hideki Moritoki, Wataru Kondoh
Publikováno v:
Biochemical and biophysical research communications. 224(2)
Triptoquinone A (TQA), which is an anti-inflammatory constituent in plants, was studied for its suppressive effect on nitric oxide production by LPS. TQA significantly suppressed smooth muscle relaxation and increase in cyclic GMP levels by nitric ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97305861825a924faf59088ab7ea3d95
https://pubmed.ncbi.nlm.nih.gov/8702429
https://pubmed.ncbi.nlm.nih.gov/8702429
Autor:
Yasuyuki Tsutsumishita, Koichiro Tsuchiya, Mineo Niwa, Kenji Fukuzawa, Yoshitaka Hamada, Takaaki Ikata, Shinsuke Katoh
Publikováno v:
Free radical biologymedicine. 20(1)
Nitric oxide (NO) was measured directly after spinal cord injury (SCI) in rats by an ESR spin-trapping technique using Fe2+ and diethyldithiocarbamate (DETC). The levels of NO and lipid peroxides expressed as thiobarbituric acid reactive substances (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c19059a03a4e01c81521e8ea499bbf1
https://pubmed.ncbi.nlm.nih.gov/8903674
https://pubmed.ncbi.nlm.nih.gov/8903674