Zobrazeno 1 - 10
of 572
pro vyhledávání: '"Yasuyuki Sakai"'
Autor:
Shant Nepal, Jinyan Si, Shohei Ishikawa, Masaki Nishikawa, Yasuyuki Sakai, Aya M. Akimoto, Hiroyuki Okada, Shinsuke Ohba, Ung-il Chung, Takamasa Sakai, Hironori Hojo
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 24-34 (2024)
With the rising prevalence of bone-related injuries, it is crucial to improve treatments for fractures and defects. Tissue engineering offers a promising solution in the form of injectable hydrogel scaffolds that can sustain the release of growth fac
Externí odkaz:
https://doaj.org/article/342edeb2f7ed45da89ffba41973f23b1
Publikováno v:
Nanomaterials, Vol 14, Iss 17, p 1435 (2024)
Pollution by microplastics and nanoplastics (MNPs) raises concerns, not only regarding their environmental effects, but also their potential impact on human health by internalization via the small intestine. However, the detailed pathways of MNP inte
Externí odkaz:
https://doaj.org/article/6b1e837185514ef3b5bd155d1f70c76d
Publikováno v:
Frontiers in Urology, Vol 4 (2024)
Kidney diseases such as glomerulopathy and nephron dysfunction are estimated to grow to more than 900 million cases by 2030, in 45% of which kidney transplantation will be required, representing a major challenge for biomedicine. A wealth of progress
Externí odkaz:
https://doaj.org/article/d028a704db604d4aa9073bd2e87cacec
Publikováno v:
IJU Case Reports, Vol 6, Iss 5, Pp 314-317 (2023)
Introduction Collision tumors are a rare phenomenon defined as two or more histologically distinct tumors that are in contact with each other. Case presentation The patient was a man with a history of end‐stage diabetic nephropathy under hemodialys
Externí odkaz:
https://doaj.org/article/c7b89689cf2749eb9f786f33f7110896
Autor:
Fuad Gandhi Torizal, Tia Utami, Qiau You Lau, Kousuke Inamura, Masaki Nishikawa, Yasuyuki Sakai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Human pluripotent stem cell-derived liver organoids (HLOs) have recently become a promising alternative for liver regenerative therapy. To realize this application, a large amount of human-induced pluripotent stem cells (hiPSCs) derived-live
Externí odkaz:
https://doaj.org/article/4ad9e4501bdb48459dd885eb61f8f9a4
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 408-417 (2021)
Ischemic stroke is a major cause of death and disability worldwide and is expected to increase in the future with the aging population. Currently, there are no clinically available treatments for damage sustained during an ischemic stroke, but much r
Externí odkaz:
https://doaj.org/article/8a5f123251ad4083b42b4dc668df1312
Autor:
Fuad Gandhi Torizal, Qiao You Lau, Masato Ibuki, Yoshikazu Kawai, Masato Horikawa, Masataka Minami, Tatsuo Michiue, Ikki Horiguchi, Masaki Nishikawa, Yasuyuki Sakai
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Although human pluripotent stem cell culture is routine, daily media changes, high cost of growth factors required in pluripotent cell media, and reproducibility of differentiation are an obstacle for the mass production of hPSCs. Here, Torizal et al
Externí odkaz:
https://doaj.org/article/a9aeb1e539894f8bb934595d323399c7
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The liver metabolizes a variety of substances that sometimes interact and regulate each other. The modeling of a single cell or a single metabolic pathway does not represent the complexity of the organ, including metabolic zonation (heterogeneity of
Externí odkaz:
https://doaj.org/article/ecd81ae7c4f3485fbc68464fcea118a8
Autor:
Masaki Nishikawa, Hiroyasu Ito, Fumiya Tokito, Keita Hirono, Kousuke Inamura, Benedikt Scheidecker, Mathieu Danoy, Takumi Kawanishi, Hirohsi Arakawa, Yukio Kato, Katsuhiro Esashika, Hiroshi Miyasako, Yasuyuki Sakai
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
In the pharmaceutical industry, primary cultured hepatocytes is a standard tool used to assess hepatic metabolisms and toxicity in vitro. Drawbacks, however, include their functional deterioration upon isolation, mostly due to the lack of a physiolog
Externí odkaz:
https://doaj.org/article/6b9bd2ba86104b5498c6de2c0db815e1
Autor:
Marie Shinohara, Hiroshi Arakawa, Yuuichi Oda, Nobuaki Shiraki, Shinji Sugiura, Takumi Nishiuchi, Taku Satoh, Keita Iino, Sylvia Leo, Yusuke Kato, Karin Araya, Takumi Kawanishi, Tomoki Nakatsuji, Manami Mitsuta, Kosuke Inamura, Tomomi Goto, Kenta Shinha, Wataru Nihei, Kikuo Komori, Masaki Nishikawa, Shoen Kume, Yukio Kato, Toshiyuki Kanamori, Yasuyuki Sakai, Hiroshi Kimura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Examining intestine–liver interactions is important for achieving the desired physiological drug absorption and metabolism response in in vitro drug tests. Multi-organ microphysiological systems (MPSs) constitute promising tools for evalua
Externí odkaz:
https://doaj.org/article/f3d6e51115fc431c979b3b6a3eb9921c