Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasuyuki Onai"'
Autor:
Hisanori Kosuge, Yasuyuki Onai, Hiroyuki Okada, Yasuhiro Maejima, Go Haraguchi, Mitsuaki Isobe, Jun-ichi Suzuki
Publikováno v:
Laboratory Investigation. 91:932-944
Unfavorable left ventricular (LV) remodeling after myocardial infarction (MI) leads to cardiac dysfunction. We examined whether Telmisartan, an angiotensin (Ang) II type I receptor blocker (ARB), could improve the recovery of LV function in a rat mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2cc7388af9c3a8e5a41b14c98e94f8
https://doi.org/10.1038/labinvest.2011.45
https://doi.org/10.1038/labinvest.2011.45
Autor:
Ryo Gotoh, Yasuyuki Onai, Yasuhiro Maejima, Miyuki Azuma, Hisanori Kosuge, Hideki Futamatsu, Mitsuaki Isobe, Go Haraguchi, Jun-ichi Suzuki, Noritaka Koga, Hitoshi Saiki, Fumihiko Tsushima
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 24:2057-2062
Background— Programmed death-1 (PD-1), a member of the CD28 family, has been identified. PD-1 is involved in the negative regulation of some immune responses. We evaluated the role of PD-ligand 1 (PD-L1) in graft arterial disease (GAD) of cardiac a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadff1246cca6517a35110a31bed73d0
https://doi.org/10.1161/01.atv.0000145015.23656.e4
https://doi.org/10.1161/01.atv.0000145015.23656.e4
Autor:
Akiko Itai, Yasuhiro Maejima, Mitsuaki Isobe, Yasuyuki Onai, Jun-ichi Suzuki, Susumu Muto, Tsunekazu Kakuta, Go Haraguchi, Hiroshi Fukasawa
Publikováno v:
Cardiovascular Research. 63:51-59
Objective : Reperfusion injury is related closely to inflammatory reactions such as activation of inflammatory cells and expression of cytotoxic cytokines. We investigated the efficacy of IκB phosphorylation blockade in a rat myocardial ischemia/rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5270d14d24d19bd1d479cf9436dff4fd
https://doi.org/10.1016/j.cardiores.2004.03.002
https://doi.org/10.1016/j.cardiores.2004.03.002
Autor:
Go Haraguchi, Yasuyuki Onai, Akiko Itai, Susumu Muto, Mitsuaki Isobe, Jun-ichi Suzuki, Yasuhiro Maejima
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 292(1)
Several studies have demonstrated that NF-κB is substantially involved in the progression of cardiac remodeling; however, it remains uncertain whether the continuous inhibition of NF-κB is effective for the prevention of myocardial remodeling. Myoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb1a1de1b8f9b4bb6f2d58ec0f1cb37
https://pubmed.ncbi.nlm.nih.gov/16920808
https://pubmed.ncbi.nlm.nih.gov/16920808
Autor:
Ryoko Wakizono Azuma, Hideki Futamatsu, Noritaka Koga, Hisanori Kosuge, Yasuyuki Onai, Masahito Ogawa, Mitsuaki Isobe, Jun-ichi Suzuki
Publikováno v:
Cardiovascular research. 64(3)
Objective : This study tested the hypothesis that 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitor affects T cell-mediated autoimmunity through inhibition of nuclear factor-κB (NFκB) and reduces the severity of experimental auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0b5cec9b63bf8d57ab85db42d3e76f
https://pubmed.ncbi.nlm.nih.gov/15537494
https://pubmed.ncbi.nlm.nih.gov/15537494
Autor:
Kurt L. Berens, Ryo Gotoh, Yasunobu Nishiwaki, Jun-ichi Suzuki, Mitsuaki Isobe, Hiroshi Ito, Yasuyuki Onai, Masayuki Yoshida, Richard A.F. Dixon
Publikováno v:
European journal of pharmacology. 481(2-3)
Reperfusion injury is related closely to inflammatory reactions such as the activation and accumulation of neutrophils. We investigated the efficacy of a novel small molecule selectin antagonist (bimosiamose) in a rat model of transient left coronary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c721d6d857f6a2c8ce783e0bbe58f345
https://pubmed.ncbi.nlm.nih.gov/14642789
https://pubmed.ncbi.nlm.nih.gov/14642789
Autor:
Jun-ichi Suzuki, Yasuhiro Maejima, Kenzo Hirao, Hiroyuki Okada, Yasuyuki Onai, Mitsuaki Isobe
Publikováno v:
Journal of Cardiac Failure. 13:S29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c2df4c6397cd21b31322e2662cebb37
https://doi.org/10.1016/j.cardfail.2007.06.123
https://doi.org/10.1016/j.cardfail.2007.06.123
Publikováno v:
In Journal of Cardiac Failure 2004 10(5) Supplement:S182-S182