Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yasuyoshi Agata"'
Autor:
Shigeru Itai, Takeru Iwamura, Shoko Tanaka, Takeaki Uchimoto, Kana Takahashi, Yasunori Iwao, Atsuo Miyagishima, Yasuyoshi Agata
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 78:492-498
To study the effect of glycerin fatty acid ester (Poem TR-FB) concentrations on the dissolution rate of acetaminophen (APAP), the dissolution and disintegration behaviors of APAP tablets formulated using various lubricants were examined. The change o
Publikováno v:
International Journal of Pharmaceutics. 414:63-68
To predict drug dissolution and understand the mechanisms of drug release from wax matrix dosage forms containing glyceryl monostearate (GM; a wax base), aminoalkyl methacrylate copolymer E (AMCE; a pH-dependent functional polymer), and acetaminophen
Publikováno v:
International journal of pharmaceutics. 428(1-2)
From wax matrix dosage forms, drug and water-soluble polymer are released into the external solvent over time. As a consequence, the pore volume inside the wax matrix particles is increased and the diffusion coefficient of the drug is altered. In the
Publikováno v:
Chemicalpharmaceutical bulletin. 58(4)
A mechanistic mathematical model was designed to predict dissolution patterns under non-sink conditions. Sulfamethoxazole was used as a model drug, and its physico-chemical properties such as solubility, density, and intrinsic dissolution rate consta