Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yasuya Inomata"'
Publikováno v:
Acta Ophthalmologica. 96:e393-e398
PURPOSE To compare the 1-year outcomes of treat-and-extend (TAE) and every-other-month (2M) regimens with intravitreal aflibercept in Japanese wet age-related macular degeneration (AMD) patients. METHODS Prospective, multicenter, randomized clinical
Autor:
Yasuhiro Ito, Akira Haga, Hidenobu Tanihara, Ayako Fukushima, Mikiko Fukushima, Eri Takahashi, Yasuya Inomata
Publikováno v:
Biochemical and Biophysical Research Communications. 470:569-574
In rhegmatogenous retinal detachment (RRD), scattered RPE cells from the basement membrane into the vitreous cavity undergo an epithelial mesenchymal transition (EMT) and form the intraocular fibrous membrane in response to vitreous fluid. We investi
Publikováno v:
Investigative ophthalmologyvisual science. 57(6)
Purpose The purpose of this study was to elucidate the differentiated expression patterns and phagocytic activities of two subtypes of microglia. Methods A rat optic nerve crush model was used to identify the expression patterns of two subtypes of mi
Autor:
Mitsuharu Ueda, M Uchino, Y. Misumi, Makoto Shono, Tomoo Hirahara, Katsuhiro Asonuma, Konen Obayashi, Taro Yamashita, Yukio Ando, Masanobu Nakamura, Hirofumi Jono, Sadahisa Okamoto, Yasuya Inomata
Publikováno v:
Neurology. 78:637-643
Familial amyloid polyneuropathy (FAP), which is a fatal disorder inherited in an autosomal dominant fashion, is characterized by systemic accumulation of polymerized transthyretin (TTR) in the peripheral nerves and systemic organs. Liver transplantat
Autor:
Ryuhei Hara, Masaru Inatani, Hidenobu Tanihara, Takahiro Kawaji, Mikiko Fukushima, Nina Sagara, Yasuya Inomata
Publikováno v:
Current Eye Research. 35:1012-1020
N-acetyl-cysteine (NAC) is a potent antioxidant known to be a precursor of glutathione. The purpose of this study was to investigate the role of NAC in the development of choroidal neovascularization (CNV).CNV was induced in C57BL/6 mice by laser pho
Autor:
Hidenobu Tanihara, Jin Tahara, Takahiro Kawaji, Nina Sagara, Yasuya Inomata, Mikiko Fukushima, Ryuhei Hara
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 248:931-936
To compare 12-month results of two single initial treatments--photodynamic therapy with verteporfin alone (PDT group), and this therapy combined with intravitreal bevacizumab (IVB) (COMB group)--for neovascular age-related macular degeneration (AMD),
Publikováno v:
Retina. 27:1074-1078
PURPOSE To demonstrate the feasibility of autologous plasmin for treatment of proliferative diabetic retinopathy. METHODS The study examined prospectively six patients with bilateral proliferative diabetic retinopathy. Comparisons of the surgical tim
Autor:
Hidenobu Tanihara, Mikiko Fukushima, Takahiro Kawaji, Akiomi Takano, Yasuya Inomata, Masaru Inatani, Nina Sagara
Publikováno v:
Experimental Eye Research. 84:1074-1080
The association between the use of statins and age-related macular degeneration (AMD), a leading cause of blindness, has been evaluated in many clinical studies; however, the results have been contradictory. We evaluated the effect of pitavastatin ad
Autor:
Koki Matsumoto, Seiya Miyajima, Hidenobu Tanihara, Motohiro Takeya, Kousuke Ikema, Yasuya Inomata, Yoshihiro Komohara
Publikováno v:
Experimental Eye Research. 83:1396-1404
This study aimed to investigate expressions and sources of matrix metalloproteinases (MMP)-2 and MMP-9, and of tissue inhibitors of MMP (TIMP)-1 and TIMP-2 in experimental Pseudomonas aeruginosa keratitis in rabbits. Pseudomonal keratitis was induced
Autor:
Norihiko Kondo, Masaki Tanito, Akie Teratani, Yasuya Inomata, Hidenobu Tanihara, Hajime Nakamura, Junji Yodoi, Takahiro Kawaji
Publikováno v:
Journal of Neurochemistry. 98:372-385
Thioredoxin (TRX) plays a variety of redox-related roles in organisms. To investigate its function as an endogenous redox regulator in NMDA-induced retinal neurotoxicity, we injected NMDA with TRX, mutant TRX or saline into the vitreous cavity of rat