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pro vyhledávání: '"Yasutsuga Ueda"'
Autor:
John A. Wichtowski, Yuan Tsai, Ken Denbleyker, Peter F. Misco, Jollie D. Godfrey, Janak Singh, Raymond F. Miller, Junius M. Clark, John D. Matiskella, Michael J. Pucci, Richard H. Mueller, Michael J. Humora, Boyhan Brenda T, Thomas P. Kissick, Joan Fung-Tomc, Stan V. D'Andrea, David R. Kronenthal, Robert K. Perrone, Yasutsuga Ueda, Annie Pullockaran, Murray A. Kaplan, Sterzycki Roman Z, James E. Heikes, Shelley E. Hoeft, Fritz Alan W, Truc Chi Vu, Rita Fox, Joanne J. Bronson, Jeffery T. North, D P Bonner, Thomas W. Hudyma
Publikováno v:
Tetrahedron. 56:5687-5698
Cephalosporin derivatives containing a unique combination of lipophilic C-7 sidechains and polar C-3 thiopyridinium groups were synthesized and found to exhibit potent anti-MRSA activity in vitro and in vivo. The optimum C-7 sidechains utilized were