Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yasuto Yamaguchi"'
Autor:
Lei Zhao, Yasuto Yamaguchi, Xiaomei Ge, William H. Robinson, John Morser, Lawrence L. K. Leung
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Chemerin is a chemoattractant involved in immunity that also functions as an adipokine. Chemerin is secreted as an inactive precursor (chem163S), and its activation requires proteolytic cleavages at its C-terminus, involving prote
Externí odkaz:
https://doaj.org/article/51b5b0537a75439d8de534b901a5e527
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202780 (2018)
Chemerin is a chemoattractant involved in immunity as well as an adipokine, whose activity is regulated by successive proteolytic cleavages at its C-terminus. Chemerin's C-terminal sequence and its proteolytic cleavage sites are highly conserved betw
Externí odkaz:
https://doaj.org/article/83b3810fb59447fda96170b15e0534be
Autor:
John Morser, William H. Robinson, Xiaomei Ge, Lei Zhao, Yasuto Yamaguchi, Lawrence L.K. Leung
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Chemerin is a chemoattractant involved in immunity that also functions as an adipokine. Chemerin is secreted as an inactive precursor (chem163S), and its activation requires proteolytic cleavages at its C-terminus, involving proteases in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a2774abf442cde23b4273f860a452b
http://link.springer.com/article/10.1186/s13075-018-1615-y
http://link.springer.com/article/10.1186/s13075-018-1615-y
Autor:
Yasuto Yamaguchi, Xiaomei Ge, Caroline Berube, John Morser, Loredana Bury, Paolo Gresele, Lei Zhao, Lawrence L.K. Leung
Publikováno v:
Blood. 131:353-364
Chemerin is a chemoattractant and adipokine that circulates in blood as inactive prochemerin (chem163S). Chem163S is activated by a series of C-terminal proteolytic cleavages resulting in diverse chemerin forms with different levels of activity. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9982ff3efbc7d08c896fba9f492c5fe5
https://doi.org/10.1182/blood-2017-07-792580
https://doi.org/10.1182/blood-2017-07-792580
Figure S1. Purification and characterization of chem156F. Following centrifugation and filtration, conditioned cell culture medium applied to an anion exchange column equilibrated with PBS (pH 7.4) and then chem156F protein eluted by a gradient of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b5b34ad1a21bf45a4ef1de69f921e1
Publikováno v:
Journal of Biological Chemistry. 286:39510-39519
Chemerin is a chemoattractant involved in innate and adaptive immunity as well as an adipokine implicated in adipocyte differentiation. Chemerin circulates as an inactive precursor in blood whose bioactivity is closely regulated through proteolytic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ce359dc72437bff657cc7a8c0d0605
https://doi.org/10.1074/jbc.m111.258921
https://doi.org/10.1074/jbc.m111.258921
Autor:
Koichi Sanse, Yasuto Yamaguchi, Kazuyoshi Yonezawa, Yoshitaka Ono, Naoaki Saito, Ken-ichi Yoshino, Noriko Oshiro, Takehiro Matsubara, Yasuhito Shirai, Masamitsu Kuriyama
Publikováno v:
Journal of Biological Chemistry. 281:31627-31637
Diacylglycerol (DAG) acts as an allosteric activator of protein kinase C (PKC) and is converted to phosphatidic acid by DAG kinase (DGK). Therefore, DGK is thought to be a negative regulator of PKC activation. Here we show molecular mechanisms of fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2018b1db2c082a2f12b8685f37eeade
https://doi.org/10.1074/jbc.m606992200
https://doi.org/10.1074/jbc.m606992200
Autor:
Miho Oyasu, Taizo Taniguchi, Naoko Adachi, Yasuhito Shirai, Naoaki Saito, Rika Takenaka, Yasuto Yamaguchi
Publikováno v:
Molecular Brain Research. 139:288-299
Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) to produce phosphatidic acid (PA) and is, therefore, a potential terminator of DG signaling. DG and PA are important intracellular second messengers. DG directly binds protein kinase C (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4284996068b075d0d067454c760ec223
https://doi.org/10.1016/j.molbrainres.2005.06.007
https://doi.org/10.1016/j.molbrainres.2005.06.007
Autor:
Xiaomei Ge1,2, Yasuto Yamaguchi1,2, Lei Zhao1,2, Bury, Loredana3, Gresele, Paolo3, Berube, Caroline1, Leung, Lawrence L.1,2, Morser, John1,2 jmorser@stanford.edu
Publikováno v:
Blood. 1/18/2018, Vol. 131 Issue 3, p353-364. 12p.
Autor:
Yasuto Yamaguchi, Paolo Gresele, Lawrence L.K. Leung, Xiaomei Ge, John Morser, Loredana Bury, Lei Zhao
Publikováno v:
Blood. 128:2561-2561
Chemerin is a chemoattractant and adipokine that circulates in blood as inactive prochemerin (chem163S). Chem163S is activated by a series of C-terminal proteolytic cleavages resulting in diverse chemerin forms with different levels of activity. Clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd0f4692ff7a89fc8ac7558f0fd7c565
https://doi.org/10.1182/blood.v128.22.2561.2561
https://doi.org/10.1182/blood.v128.22.2561.2561