Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Yasutaka, Anraku"'
Autor:
Akiko Amano, Nobuo Sanjo, Wataru Araki, Yasutaka Anraku, Makoto Nakakido, Etsuro Matsubara, Takami Tomiyama, Tetsuya Nagata, Kouhei Tsumoto, Kazunori Kataoka, Takanori Yokota
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Although a large amount of evidence has revealed that amyloid β (Aβ), especially Aβ oligomers, protofibrils, and pyroglutamated Aβs, participate primarily in the pathophysiological processes of Alzheimer’s disease, most clin
Externí odkaz:
https://doaj.org/article/8b45c3e51a3b4087b398375c02604d43
Publikováno v:
Nano Select, Vol 3, Iss 8, Pp 1242-1251 (2022)
Abstract Macrocyclic drugs are promising agents for treating a variety of diseases. However, these compounds usually present delivery limitations, such as low tissue selectivity and poor cellular uptake, which may impair efficacy and clinical transla
Externí odkaz:
https://doaj.org/article/de9a7edb73964e1c8a9d5b58d412abd4
Autor:
Yasuhiro Nakagawa, Kotaro Ushidome, Keita Masuda, Kazunori Igarashi, Yu Matsumoto, Tatsuya Yamasoba, Yasutaka Anraku, Madoka Takai, Horacio Cabral
Publikováno v:
Polymers, Vol 15, Iss 12, p 2626 (2023)
Multi-arm star-shaped block copolymers with precisely tuned nano-architectures are promising candidates for drug delivery. Herein, we developed 4- and 6-arm star-shaped block copolymers consisting of poly(furfuryl glycidol) (PFG) as the core-forming
Externí odkaz:
https://doaj.org/article/05ebbd6bbbe94378a26271f58bba3314
Autor:
Takayoshi Watanabe, Hayato Laurence Mizuno, Jumpei Norimatsu, Takumi Obara, Horacio Cabral, Kouhei Tsumoto, Makoto Nakakido, Daisuke Kawauchi, Yasutaka Anraku
Publikováno v:
Polymers, Vol 15, Iss 7, p 1808 (2023)
Medulloblastoma is a life-threatening disease with poor therapeutic outcomes. In chemotherapy, low drug accumulation has been a cause of these outcomes. Such inadequate response to treatments has been associated with low drug accumulation, particular
Externí odkaz:
https://doaj.org/article/ca70030fc8184e25aefc90e0dbf2b119
Publikováno v:
Polymers, Vol 15, Iss 6, p 1368 (2023)
Mesoscopic-sized polyion complex vesicles (PICsomes) with semi-permeable membranes are promising nanoreactors for enzyme prodrug therapy (EPT), mainly due to their ability to accommodate enzymes in their inner cavity. Increased loading efficacy and r
Externí odkaz:
https://doaj.org/article/0df6e6b82403463ab9d66236136871c7
Publikováno v:
Chemistry Letters; May2024, Vol. 53 Issue 5, p1-5, 5p
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6686 (2022)
Coronary stenosis has been one of the most common heart diseases that drastically increases the risk of fatal disorders such as heart attack. Angioplasty using drug coated balloons (DCB) has been one of the most safe and promising treatments. To mini
Externí odkaz:
https://doaj.org/article/9f4edc1604af4251aa87fcdadea8599a
Autor:
Cabral, Yasuhiro Nakagawa, Kotaro Ushidome, Keita Masuda, Kazunori Igarashi, Yu Matsumoto, Tatsuya Yamasoba, Yasutaka Anraku, Madoka Takai, Horacio
Publikováno v:
Polymers; Volume 15; Issue 12; Pages: 2626
Multi-arm star-shaped block copolymers with precisely tuned nano-architectures are promising candidates for drug delivery. Herein, we developed 4- and 6-arm star-shaped block copolymers consisting of poly(furfuryl glycidol) (PFG) as the core-forming
Autor:
Noriko Nakamura, Yuki Mochida, Kazuko Toh, Shigeto Fukushima, Horacio Cabral, Yasutaka Anraku
Publikováno v:
Polymers, Vol 13, Iss 1, p 5 (2020)
Self-assembled supramolecular structures based on polyion complex (PIC) formation between oppositely charged polymers are attracting much attention for developing drug delivery systems able to endure harsh in vivo environments. As controlling polymer
Externí odkaz:
https://doaj.org/article/b0ae107d67e443d998cd1874ee9a8918
Autor:
Horacio Cabral, Jinbing Xie, Yasutaka Anraku, Hiroaki Kinoh, Hang Zhou, Yuki Mochida, Tao Yang, Kazunori Kataoka, Xueying Liu
Publikováno v:
Nature Biomedical Engineering. 5:1274-1287
Because of the blood–tumour barrier and cross-reactivity with healthy tissues, immune checkpoint blockade therapy against glioblastoma has inadequate efficacy and is associated with a high risk of immune-related adverse events. Here we show that an