Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yasushi Shikata"'
Autor:
Noriyuki Kataoka, Yasushi Shikata, Kenichi Shikata, Hirofumi Makino, Kazuyoshi Omori, Shingo Nishishita, Naomi Watanabe, Kei Sarai, Noriko Goda, Motofumi Sasaki, Jun Wada
Publikováno v:
American Journal of Physiology-Cell Physiology. 297:C945-C954
Recently, sphingosine 1-phosphate (S1P) has been highlighted as an endothelial barrier-stabilizing mediator. FTY720 is a S1P analog originally developed as a novel immunosuppressant. The phosphorylated form of FTY720 binds to S1P receptors to exert S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7d6a6931f4efc9a7aaf56fd03a8b63
https://doi.org/10.1152/ajpcell.00606.2008
https://doi.org/10.1152/ajpcell.00606.2008
Autor:
Mitsuhiro Iwahashi, Kazuo Akima, Jun Wada, Yasushi Shikata, Shinichi Okada, Hirofumi Makino, Kenichi Shikata, Mitsuhiro Matsuda, Yoshinori Tsuchiyama, Daisuke Ogawa
Publikováno v:
Nephron Experimental Nephrology. 99:e26-e32
Background/Aims: Sulfated polysaccharides are known to interfere with the binding of selectins and their ligands. Recently, we demonstrated that sulfated hyaluronic acid (SHA), a synthetic sulfated polysaccharide, showed preventive and therapeutic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed0d6af6d9d8749150b4cb10529cf5c
https://doi.org/10.1159/000081795
https://doi.org/10.1159/000081795
Autor:
Hikaru Sugimoto, Masaki Fukushima, Yasushi Shikata, Kenichi Shikata, Hirofumi Makino, Tetsuji Yamashita, Isao Kumagai, Jun Wada, Keita Hiragushi, Nobuyuki Miyatake
Publikováno v:
ResearcherID
Glomerular hyperfiltration plays a pathogenic role in the early stages of diabetic nephropathy. Experimental studies in laboratory animals suggest that nitric oxide (NO) might be involved in the pathogenesis of glomerular hyperfiltration. We performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91ccb01ab63467be26718d6a2f40af9
https://doi.org/10.1016/s0168-8227(01)00260-1
https://doi.org/10.1016/s0168-8227(01)00260-1
Autor:
Naoki Asakawa, Yasushi Shikata, Atsushi Koide, Manabu Kuwada, Yuichirou Hayashi, Akira Hashimoto
Publikováno v:
Analytica Chimica Acta. 365:241-247
A novel peptide-mapping method for recombinant human tissue-type plasminogen activator is described. It involves reduction and S -carboxyamidemethylation of the tissue-type plasminogen activator and digestion of the alkylated protein with lysyl endop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27bfe3a2b428926b68c03ddd0f71ad5f
https://doi.org/10.1016/s0003-2670(97)00603-x
https://doi.org/10.1016/s0003-2670(97)00603-x
Autor:
Hikaru Sugimoto, Yasushi Shikata, Hirofumi Makino, Kenichi Shikata, Masahiko Kushiro, Jun Wada, Nobuyuki Miyatake, Masayuki Miyasaka
Publikováno v:
ResearcherID
Therapeutic effects of prostacyclin analog on crescentic glomerulonephritis of rat . Prostacyclin (PGI 2 ) is known to have a relaxative action on vascular smooth muscle, an inhibitory action against platelet activation and neutrophil function. Previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abda6f41a539994d11136aa6f0f692a3
Autor:
Hirofumi Makino, Masayuki Miyasaka, Saeko Ogawa, Yoshiko Hayashi, Nobuyuki Miyatake, Masahiko Kushiro, Yasushi Shikata, Kenichi Shikata, Hikaru Sugimoto
Publikováno v:
Nephron. 79:91-98
Mononuclear cells, primarily macrophages and lymphocytes, infiltrate the renal glomeruli and are involved in the progression of various glomerular diseases. Intercellular adhesion molecule 1 (ICAM-1) is expressed on the vascular endothelium and media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7063d920b11d5a737663a76681192e2
https://doi.org/10.1159/000044997
https://doi.org/10.1159/000044997
Autor:
Alison MacLeod, Kumeo Ono, Rida Bitar, Ivan Rychlik, Neva E. Haites, Gert Jensen, Jan Těmínová, B.A.C. Van Acker, Yoshio Suzuki, Akiyasu Tsutida, Kazuo Kumano, A.M. Brownjohn, Yoshikazu Hayashi, Tokuhiro Okada, Hye Won Park, Karel Němeček, Kazuto Inose, Yong Choi, Masakazu Fukuda, Hans Hedenström, Yoshio Ueno, Crkovská J, G.C.M. Koomen, M. Itoh, Mitsuhiro Matsuda, Hae Il Cheong, T. Sato, Tadasu Sakai, Marie Urabe, Il Soo Ha, S. Fletcher, Tadanobu Goya, Hisashi Hashimoto, Göran Wegenius, Minoru Komai, Belen Martín, Fumihiko Hinoshita, Y. Takemoto, Yasushi Isami, Visith Sitprija, Fumiaki Marumo, Hikaru Sugimoto, Robert Mlynski, Jong Kwan Jun, Mario Bonomini, Makoto Haga, S. Inomata, John Simpson, J.E. Aaron, HyungNam Moon, Kiyosi Uehara, Poledne R, R.G. Jones, M.S. Oh, J.W. Groothoff, M. Niwa, Takuji Naruse, H. Edney, S. Shaldon, Tsukasa Nakamura, M.L. Halperin, M. Tsuchiya, B. Oldroyd, Masayuki Onai, Björn Wikström, Shintaro Yano, Yasuhiko Tomino, Vladimír Tesař, Virat Vattanavongs, Stanislav Štípek, Hirofumi Makino, Shigeo Tomura, Graham S. Hillis, George Metry, Kwang Wook Ko, P.C. Wever, Kenichi Shikata, Gakusen Nishihara, P. Harnden, Tomáš Zima, Kenzo Matsuo, Marie-Paule Carreno, Kazuhito Takeda, Neil G. McKay, Yasushi Shikata, Isao Ebihara, José M. López-Novoa, T. Kishimoto, Chikao Yasunaga, L. Arisz, L.D. Hordon, Akira Yamada, Zensuke Ota, H.C. Rayner, Toru Hyodo, Juan F. Macías-Nuñez, Hikaru Koide, Lesley A. Duthie, Takanobu Sakemi, K. Tsuchida, Bo G. Danielson, Keitaro Yokoyama, B. Buis, Sanjay Mistry, Nicole Haeffner-Cavaillon, J.H. Turney, Masahiko Kushiro, Shigeko Hara, R.T. Krediet, Yosuke Ogura, Masahiko Nakamoto, M.A. Smith, Miroslav Merta, S. Yamagami, Patrizia Santarelli, Kenji Akiyama, Nicola Settefrati, Mattias Aurell, Stefano Stuard, Pláteník J, H. Imai, Alberto Albertazzi, Tongprakob Siriwanij
Publikováno v:
Nephron. 75:I-VIII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff5d22b460c92b817beb5b78b5e61e5
https://doi.org/10.1159/000189573
https://doi.org/10.1159/000189573
Autor:
Tadashi Sato, Naoki Asakawa, Hiroshi Ohe, Yasushi Shikata, Yutaka Yoshida, Nariyasu Mano, Yoshiya Oda
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 42:25-33
In the combination of liquid chromatography (LC)-fast atom bombardment mass spectrometry (FABMS), a new frit postcolumn addition of matrix (frit-PAM) system was designed to overcome the problems such as the diffusion of analytes and the ineffective i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30857d6e98fe2b41e5d4d94798b0b4ac
https://doi.org/10.5702/massspec.42.25
https://doi.org/10.5702/massspec.42.25
Autor:
Yasushi Shikata, Yukio Ohya, Yuichiro Hayashi, Yutaka Yoshida, Komei Fukushima, Toshio Seto, Kentaro Yoshimatsu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1163:243-249
The amino-acid sequence of purified recombinant pro-major basic protein from Chinese hamster kidney cells was determined to verify the primary structure and glycosylation sites. Reduced and S-carboxamidemethylated protein was first digested with Achr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c974a5a809e4f129b059f3c628b07a
https://doi.org/10.1016/0167-4838(93)90158-n
https://doi.org/10.1016/0167-4838(93)90158-n
Autor:
Yasushi Shikata, Lichun Wang, Kenichi Shikata, Hirofumi Makino, Xiaoguang Sun, Joe G.N. Garcia, Kazuyoshi Ohmori, Konstantin G. Birukov, Jun Wada, Naoko Watanabe, Jeffrey R. Jacobson, Steven M. Dudek
Publikováno v:
Microvascular research. 77(3)
Sphingosine 1-phosphate (S1P) is an important vascular barrier regulatory agonist which enhances the junctional integrity of human lung endothelial cell monolayers. We have now demonstrated that S1P induced cortical actin ring formation and redistrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685a2ec99d4c81975f0e290236d5f593
https://pubmed.ncbi.nlm.nih.gov/19323978
https://pubmed.ncbi.nlm.nih.gov/19323978