Výsledky vyhledávání - "Yasushi Saga"

Akademický článek

The role of non‐genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell death

Autor: Takahiro Koyanagi, Yasushi Saga, Yoshifumi Takahashi, Kohei Tamura, Takahiro Yoshiba, Suzuyo Takahashi, Akiyo Taneichi, Yuji Takei, Hiroaki Mizukami, Hiroyuki Fujiwara

Publikováno v: Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)

Abstract Background Progesterone therapy is a relatively inexpensive treatment option for endometrial and breast cancers, with few side effects. Two signaling pathways usually mediate the physiological effects of progesterone, namely genomic and non�

Externí odkaz: https://doaj.org/article/b98a1a1c0e084a8fb03d2111566f0e9c

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Akademický článek

Ovarian vein thrombosis after bilateral adnexectomy in a symptomatic patient with concomitant pulmonary embolism: A case report

Autor: Yoshifumi Takahashi, Shigeki Matsubara, Kohei Tamura, Takahiro Koyanagi, Takahiro Yoshiba, Suzuyo Takahashi, Akiyo Taneichi, Yuji Takei, Yasushi Saga, Hiroyuki Fujiwara

Publikováno v: Taiwanese Journal of Obstetrics & Gynecology, Vol 62, Iss 4, Pp 559-561 (2023)

Objective: Ovarian vein thrombosis (OVT) after adnexectomy is usually asymptomatic, and pulmonary embolism (PE) has not been reported following this type of OVT. We present the case of a patient with symptomatic OVT after bilateral adnexectomy who ex

Externí odkaz: https://doaj.org/article/1699e051135a4e8183e8590f5be68097

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Akademický článek

Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells

Autor: Kohei Tamura, Hideyo Miyato, Rihito Kanamaru, Ai Sadatomo, Kazuya Takahashi, Hideyuki Ohzawa, Takahiro Koyanagi, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama

Publikováno v: Heliyon, Vol 8, Iss 6, Pp e09730- (2022)

Purpose: Although neutrophil extracellular traps (NETs) are present in various tumors, their roles in tumor biology have not been clarified yet. In this study, we examined how NETs affect the pharmacokinetics and effects of doxorubicin (DOX). Methods

Externí odkaz: https://doaj.org/article/1b9d2147deb4475da355a6d7062498dc

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Akademický článek

Knockout of vasohibin‐2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer

Autor: Takahiro Koyanagi, Yasushi Saga, Yoshifumi Takahashi, Kohei Tamura, Takahiro Yoshiba, Suzuyo Takahashi, Akiyo Taneichi, Yuji Takei, Masashi Urabe, Hiroaki Mizukami, Hiroyuki Fujiwara

Publikováno v: Cancer Medicine, Vol 10, Iss 8, Pp 2732-2739 (2021)

Abstract Vasohibin‐1 (VASH1) is a VEGF‐inducible endothelium‐derived angiogenesis inhibitor, and vasohibin‐2 (VASH2), its homolog, exhibits proangiogenic activity. VASH2 is expressed by various cancer cells and accelerates tumor angiogenesis

Externí odkaz: https://doaj.org/article/0da36932a61e4003aa5d87e4606cc9b5

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Akademický článek

Disseminated Intravascular Coagulopathy Caused by Uterine Leiomyoma with Sarcoma-Like Findings on Magnetic Resonance Imaging

Autor: Akiyo Taneichi, Hiroyuki Fujiwara, Yukako Mizoguchi, Shizuo Machida, Hiroaki Nonaka, Yuji Takei, Yasushi Saga, Mitsuaki Suzuki

Publikováno v: Case Reports in Obstetrics and Gynecology, Vol 2014 (2014)

A leiomyoma rarely causes disseminated intravascular coagulopathy (DIC). In the present report, we describe a case of DIC caused by leiomyoma. A 36-year-old nulliparous woman presented with hypermenorrhea and a lower abdominal mass. On magnetic reson

Externí odkaz: https://doaj.org/article/fccc8e2b54a441b9a42693cad4c4919a

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Akademický článek

Community-based interventions to improve HPV vaccination coverage among 13- to 15-year-old females: measures implemented by local governments in Japan.

Autor: Hiroyuki Fujiwara, Yuji Takei, Yoshiki Ishikawa, Yasushi Saga, Shizuo Machida, Akiyo Taneichi, Mitsuaki Suzuki

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84126 (2013)

The purpose of this study was to examine the effect of various community-based interventions in support of HPV vaccination implemented by cities and towns within Tochigi prefecture, Japan with a view to identifying useful indicators which might guide

Externí odkaz: https://doaj.org/article/0139e45254624b23b6dc375cb51f3e97

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