Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yasushi Mitachi"'
Autor:
Akihito Tsuji, Yukari Tanaka, Masahiro Takahashi, Naoyoshi Onoda, Kosei Hirakawa, Tetsuhiko Shirasaka, Toshiki Kamano, Keisuke Oikawa, Yasushi Mitachi, Satoshi Morita, Junichi Sakamoto, Naoyuki Taenaka, Shigetoyo Saji, Bunzo Nakata, Mariko Kambe
Publikováno v:
Oncology. 79:337-342
Aims: The efficacy and the toxicity of oral fluorouracil derivative S-1 plus low-dose cisplatin in unresectable or recurrent gastric cancer were evaluated by a phase II study. Methods: S-1 was administered orally for 28 days following 14 days’ rest
Autor:
Koichi Hirata, Akihito Tsuji, T. Takeuchi, Tetsuhiko Shirasaka, Kosei Hirakawa, Yasushi Mitachi, Susumu Yamamitsu, Bunzo Nakata
Publikováno v:
Clinical Oncology. 18:678-683
Aims The effects of haematological adverse events on the prognosis of patients with gastric cancer were investigated. Materials and methods We retrospectively analysed the association between haematological adverse events and prognosis in 23 patients
Autor:
Makio Gamoh, Takashi Yoshioka, Ryunosuke Kanamaru, Yasushi Mitachi, Kouji Sekikawa, Yuh Sakata, Soh Saitoh, Masanori Terashima
Publikováno v:
Gastric Cancer. 6:153-158
Both docetaxel (TXT) and irinotecan (CPT-11) are active chemotherapeutic agents for gastric cancer. We designed a biweekly administration regimen of TXT combined with CPT-11 for 4 weeks as one cycle in patients with inoperable or recurrent gastric ca
Autor:
Nobuteru Kikkawa, Keisuke Aiba, Yasushi Mitachi, Kazuo Shirouzu, Minoru Kurihara, Akira Wakui, Noboru Horikoshi, Yuh Sakata, Atsushi Sato
Publikováno v:
Anti-Cancer Drugs. 10:741-748
Raltitrexed (Tomudex), a novel folate-based inhibitor of thymidylate synthase, has demonstrated anti-tumour efficacy comparable with 5-fluorouracil and leucovorin in patients with advanced colorectal cancer (CRC). This phase II study was conducted to
Autor:
Chikashi Ishioka, Takao Suzuki, Masato Sakayori, Satoshi Kato, Ryunosuke Kanamaru, Hideki Shimodaira, Akira Shimada, Yasushi Mitachi, Asamura M
Publikováno v:
Genes, Chromosomes and Cancer. 21:290-297
APC gene mutations play a role in the initiation step of colorectal carcinogenesis in both familial adenomatous polyposis (FAP) and non-FAP patients. Almost all of the APC mutations are nonsense or frameshift mutations, which truncate the APC protein
Publikováno v:
The Tohoku Journal of Experimental Medicine. 163:279-288
Intravenously or intraperitoneally administered Chromomycin A3 (CHRM), an anticancer drug, augmented natural killer (NK) activity of both spleen cells and peritoneal exudate cells in BALB/c mice. When CHRM was administered intravenously, NK activity
Autor:
Kosei Hirakawa, Shigetoyo Saji, Bunzo Nakata, Junichi Sakamoto, Satoshi Morita, Tetsuhiko Shirasaka, Yasushi Mitachi, Yasuo Ohashi, Akihito Tsuji
Publikováno v:
Japanese journal of clinical oncology. 37(12)
Objective: We conducted a Phase I study to evaluate the safety and efficacy of a combination of S-1 with semi-weekly low-dose cisplatin in patients with unresectable/recurrent gastric cancer to determine the recommended dose (RD) for a subsequent Pha
Autor:
Naoya, Ishibashi, Yasushi, Mitachi, Shigeo, Sugawara, Shigeru, Shinozaki, Makoto, Miura, Takeo, Fukuju, Yoshiaki, Katahira, Kaneki, Koyama, Nanako, Fujikawa, Taizo, Kato, Kazuhiro, Murakami
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 34(11)
We report a case of angiosarcoma of the right atrium presenting superior vena cava syndrome. The patient was a 61-year-old man. Echocardiography, CT and MRI revealed a tumor arising in the anterior wall of the right atrium. The tumor was hen-egg size
Autor:
Bunzo Nakata, Kosei Hirakawa, Akihito Tsuji, Koichi Hirata, Susumu Yamamitsu, Yasushi Mitachi, Tetsuhiko Shirasaka
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(5)
Purpose: The Japanese Foundation for Multidisciplinary Treatment of Cancer conducted a Phase I study of a novel oral fluorouracil derivative, S-1, combined with a low dose of cisplatin in unresectable and recurrent gastric cancer. Experimental Design
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 30(5)
The patient was a 61-year-old man who had gastric cancer with metastasis to cervical lymph nodes and pulmonary lymphangitis carcinomatosa. He received daily oral administration of 120 mg of TS-1 (day 1-21) and systemic administration of 100 mg of CDD