Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Yasushi Koiwaya"'
Autor:
Shuji, Hirano, Takuroh, Imamura, Takeshi, Matsuo, Yuichiro, Ishiyama, Johji, Kato, Kazuo, Kitamura, Yasushi, Koiwaya, Tanenao, Eto ∗
Publikováno v:
In Journal of Cardiac Failure 2000 6(2):120-129
Autor:
Takuroh Imamura, Yasushi Koiwaya, Takeshi Matsuo, Tanenao Eto, Tetsunori Ishikawa, Masakazu Maeno, Toshiro Nagoshi, Hisamitsu Onitsuka, Yoshitake Fujiura, Kazuya Mishima, Haruhiko Date, Ryosai Nakamura
Publikováno v:
Circulation Journal. 66:773-776
A 67-year-old female non-smoker, who had been diagnosed with familial hypercholesterolemia associated with severe atherosclerosis of the coronary, carotid and vertebral arteries, developed interstitial pneumonia 4 months after initiating ticlopidine
Autor:
Shuji Hirano, Takuroh Imamura, Hisamitsu Onitsuka, Kazuo Kitamura, Takeshi Matsuo, Tanenao Eto, Yasushi Koiwaya
Publikováno v:
Circulation Journal. 66:397-402
To determine whether acute pressure overload (POL) can stimulate adrenomedullin (AM) production, the response of ventricular AM gene expression and plasma AM concentration to aortic banding was investigated in the rat. Furthermore, any link between A
Autor:
Yasushi Koiwaya, Tanenao Eto, Kenji Kuwasako, Takuroh Imamura, Kenji Kangawa, Toshihiro Tsuruda, Johji Kato, Kazuo Kitamura
Publikováno v:
Life Sciences. 69:239-245
Proadrenomedullin N-terminal 20 peptide (PAMP) is generated from post-transcriptional enzymatic processing of a 185-amino acid precursor for adrenomedullin (AM), a potent vasodilator peptide. We have reported that AM is secreted from cultured neonata
Autor:
Yasushi Koiwaya, Yoshio Yazaki, Issei Komuro, Tanenao Eto, Johji Kato, Takuroh Imamura, Toshihiro Tsuruda, Kenji Kangawa, Kazuo Kitamura
Publikováno v:
Hypertension. 35:1210-1214
Abstract —Adrenomedullin (AM) is secreted from cultured cardiac myocytes. In this study, we examined whether mechanical stretching stimulates AM production in cardiac myocytes, and if so, whether angiotensin II (Ang II) is involved in that mechanis
Autor:
Yasushi Koiwaya, Tanenao Eto, Tetsuo Tsuji, Kenji Kangawa, Kenji Kuwasako, Mari Kawamoto, Kazuo Kitamura, Toshihiro Tsuruda, Takuroh Imamura, Johji Kato
Publikováno v:
Cardiovascular Research. 43:958-967
Objective: The aim of the present study was to determine the role of adrenomedullin (AM) in cardiac fibroblasts. Methods: The production and secretion of AM were examined in cultured neonatal rat cardiac fibroblasts, and the effects of AM on prolifer
Publikováno v:
Life Sciences. 64:2505-2509
In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation. We earlier showed that both molecular forms
Autor:
Kenji Kangawa, Yasushi Koiwaya, Tanenao Eto, Tetsuo Tsuji, Naoteru Hirayama, Takuroh Imamura, Kazuo Kitamura, Johji Kato
Publikováno v:
Journal of Endocrinology. 160:297-303
In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation. We recently reported tha
Autor:
Junichiro Sakata, Yasushi Koiwaya, Shuji Hirano, Takuroh Imamura, Yuichiro Ishiyama, Takeshi Matsuo, Tanenao Eto, Kazuo Kitamura
Publikováno v:
Hypertension Research. 21:23-28
Adrenomedullin (AM) is a peptide with potent vasodilatory and hypotensive properties. Plasma AM levels in rats with experimentally induced hypertension, such as Dahl salt-sensitive rats and two-kidney, one-clip hypertensive rats, are higher than thos
Autor:
Johji Kato, Kenji Kuwasako, Yasushi Koiwaya, Tanenao Eto, Toshihiro Tsuruda, Kazuo Kitamura, Kenji Kangawa, Takuroh Imamura, Tetsuo Tsuji
Publikováno v:
Hypertension. 31:505-510
Adrenomedullin (AM), a potent vasodilator peptide, exists in the cardiac ventricle; however, the role of AM in the ventricular tissue remains unknown. In the present study, we investigated the production and secretion of AM in cultured neonatal rat c