Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yasushi Kikuta"'
Autor:
Hideyuki Yamada, Takumi Ishida, Yuji Ishii, Hiroshi Uchi, Yasushi Kikuta, Hitoshi Kurose, Yukiko Komiya, Takehiko Yokomizo, Takao Shimizu, Takayuki Koga, Masutaka Furue, Tomoki Takeda, Michio Nakaya
Publikováno v:
The Journal of biological chemistry. 292(25)
Dioxin and related chemicals alter the expression of a number of genes by activating the aryl hydrocarbon receptors (AHR) to produce a variety of disorders including hepatotoxicity. However, it remains largely unknown how these changes in gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebdbea75bf5863e14c86d4b7739b90e
https://pubmed.ncbi.nlm.nih.gov/28487374
https://pubmed.ncbi.nlm.nih.gov/28487374
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1771:1439-1445
We investigated expression of the CYP4F subfamily in human leukocytes by flow cytometry using anti-CYP4F3A antibody and quantitative reverse transcription-polymerase chain reaction (QRT-PCR). More than 90% of CD11b, CD13, CD14, CD33, and eosinophil m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2a88912a54464e72c183977bd33a08
https://doi.org/10.1016/j.bbalip.2007.10.004
https://doi.org/10.1016/j.bbalip.2007.10.004
Inflammation resolved by retinoid X receptor‐mediated inactivation of leukotriene signaling pathways
Autor:
Henry W. Strobel, Madeleine Duvic, Ying Wang, Liping Du, Auinash Kalsotra, Patricia A. Ladd, Alan S. Boyd, Yasushi Kikuta, Diane S. Keeney
Publikováno v:
The FASEB Journal. 22:538-547
Leukotrienes are implicated in the pathogenesis of diverse, inflammation-driven diseases. Metabolic inactivation of leukotriene signaling is an innate response to resolve inflammation, yet little is known of mechanisms regulating disposition of leuko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1354608a045d03eaeebda625263e28ae
https://doi.org/10.1096/fj.07-9244com
https://doi.org/10.1096/fj.07-9244com
Autor:
Edward T. Morgan, Yasushi Kikuta, Auinash Kalsotra, Chad L. Brommer, Henry W. Strobel, Sayeepriyadarshini Anakk
Publikováno v:
Archives of Biochemistry and Biophysics. 461:104-112
Cytochrome P450 (CYP) 4F mediated leukotriene B(4) (LTB(4)) metabolism modulates inflammation during injury and infection. Here we show that in addition to LTB(4), the recombinant rat CYP4Fs catalyze omega-hydroxylations of lipoxin A(4), and hydroxye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce3610e93368a210c7df72b6568ec75
https://doi.org/10.1016/j.abb.2007.02.027
https://doi.org/10.1016/j.abb.2007.02.027
Publikováno v:
Toxicology and Applied Pharmacology. 199:295-304
We previously reported the cDNA cloning of a new CYP4F isoform, CYP4F11. In the present study, we have expressed CYP4F11 in Saccharomyces cerevisiae and examined its catalytic properties towards endogenous eicosanoids as well as some clinically relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064a570b3142ac6114db5e5b9ef5d67b
https://doi.org/10.1016/j.taap.2003.12.033
https://doi.org/10.1016/j.taap.2003.12.033
Publikováno v:
International Congress Series. 1233:139-142
We have investigated the catalytic properties of recombinant proteins of two human leukotriene B4 (LTB4) ω-hydroxylases (CYP4F2 and CYP4F3) as well as the gene structures of these closely related enzymes. When expressed in yeast cells and purified t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7cebbafa41d4ca8f49982a8a2761de8
https://doi.org/10.1016/s0531-5131(02)00289-3
https://doi.org/10.1016/s0531-5131(02)00289-3
Publikováno v:
Biochemical Pharmacology. 62:249-254
Earlier, we isolated and purified five different P450 isoforms from rabbit kidney cortex microsomes, three of which are members of the CYP4A subfamily (CYP4A5, CYP4A6, and CYP4A7), with the others being CYP2B4 and CYP1A1. In contrast, P450s in paroti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d128f7c317f85b79792f518957c4bd6
https://doi.org/10.1016/s0006-2952(01)00655-4
https://doi.org/10.1016/s0006-2952(01)00655-4
Publikováno v:
Archives of Biochemistry and Biophysics. 383:225-232
We have isolated a cDNA for a mouse leukotriene B4 omega-hydroxylase, CYP4F14. The cDNA encoded a protein with 524 amino acids, whose sequence similarity is 95% that of rat CYP4F1. The microsomes from yeast cells transfected with CYP4F14 expression v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdae8e37a3f364357843b13af8daee0
https://doi.org/10.1006/abbi.2000.2078
https://doi.org/10.1006/abbi.2000.2078
Autor:
Tatsunori Takimoto, Yasushi Kikuta, Tamotsu Tanaka, Kiyoshi Satouchi, Takayuki Sugiura, Jun-ichi Morishige
Publikováno v:
Biochemical and Biophysical Research Communications. 264:683-688
In mammalian tissues and cells, a characteristic of phosphatidylinositol (PI) is a high abundance of arachidonic acid (AA) relative to the other phospholipids. In this study, we investigated the effects of supplementation of several polyunsaturated f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2e20dab8fabd6c569788430e63afc8
https://doi.org/10.1006/bbrc.1999.1559
https://doi.org/10.1006/bbrc.1999.1559
Publikováno v:
Archives of Biochemistry and Biophysics. 369:193-196
CYP4F1 was discovered by Chen and Hardwick ( Arch. Biochem. Biophys. 300, 18–23, 1993) as a new CYP4 cytochrome P450 (P450) preferentially expressed in rat hepatomas. However, the catalytic function of this P450 remained poorly defined. We have pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537b8c663a8ea1521b653382563b10b7
https://doi.org/10.1006/abbi.1999.1271
https://doi.org/10.1006/abbi.1999.1271