Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yasushi Kasahara"'
NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
Autor:
Yudai Murayama, Yasushi Kasahara, Nobuhiro Kubo, Chansu Shin, Masaru Imamura, Naoki Oike, Takashi Ariizumi, Akihiko Saitoh, Minori Baba, Tomohiro Miyazaki, Yuko Suzuki, Yiwei Ling, Shujiro Okuda, Keichiro Mihara, Akira Ogose, Hiroyuki Kawashima, Chihaya Imai
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101521- (2022)
Background: T-cell receptor-engineered T-cell therapies have achieved promising response rates against synovial sarcoma in clinical trials, but their applicability is limited owing to the HLA matching requirement. Chimeric antigen receptor (CAR) can
Externí odkaz:
https://doaj.org/article/c609994a7bb64a339226a58c982ae86f
Autor:
Yudai Murayama, Hiroyuki Kawashima, Nobuhiro Kubo, Chansu Shin, Yasushi Kasahara, Masaru Imamura, Naoki Oike, Takashi Ariizumi, Akihiko Saitoh, Keichiro Mihara, Hajime Umezu, Akira Ogose, Chihaya Imai
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101227- (2021)
Background: Synovial sarcoma is a rare malignant soft-tissue tumor that is prevalent in adolescents and young adults, and poor prognosis has been reported in patients with metastatic lesions. Chimeric antigen receptor (CAR) T-cell therapy is an emerg
Externí odkaz:
https://doaj.org/article/3efb67dd5b6e4e1d870799f5111765b4
Autor:
Yasushi Kasahara, Masaru Imamura, Chansu Shin, Hiroshi Shimizu, Jirou Utsumi, Ryosuke Hosokai, Haruko Iwabuchi, Takayuki Takachi, Akiyoshi Kakita, Hirokazu Kanegane, Akihiko Saitoh, Chihaya Imai
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Chronic enteroviral meningoencephalitis is a well-known complication in patients with X-linked agammaglobulinemia (XLA). However, progressive neurodegenerative disorders or chronic neuroinflammatory diseases with no causative microorganisms have been
Externí odkaz:
https://doaj.org/article/6bb8052929c74f16b3c2ca4638e01a36
Autor:
Yasushi Kasahara, Chansu Shin, Nobuhiro Kubo, Keichiro Mihara, Haruko Iwabuchi, Takayuki Takachi, Masaru Imamura, Akihiko Saitoh, Chihaya Imai
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objectives One of the reasons as to why chimeric antigen receptors (CAR)‐T cell therapy for malignancies other than CD19‐ or BCMA‐positive tumors has yet to produce remarkable progress is the paucity of targetable antigens. NKp44 is on
Externí odkaz:
https://doaj.org/article/2c263e5bfe4048dc925fc78e6bafae1d
Autor:
Maria Solovieva, Alexander Rozhnoi, Masashi Hayakawa, Yasushi Kasahara, Yasuhide Hobara, Yuichi Ida, Yuya Ono, Oleg A. Molchanov, Kenji Ohta
Publikováno v:
Annals of Geophysics, Vol 55, Iss 1 (2012)
The presence of ionospheric perturbations in possible association with two huge earthquakes (Noto-hanto peninsula and Niigata-chuetu-oki earthquakes) in 2007 was studied on the basis of a conventional statistical study for a particular propagation pa
Externí odkaz:
https://doaj.org/article/98e6d8830d3141128e061afe3c5465b4
Autor:
Masashi Hayakawa, Yasuhide Hobara, Alexander Rozhnoi, Maria Solovieva, Kenji Ohta, Jun Izutsu, Tohru Nakamura, Yasushi Kasahara
Publikováno v:
Terrestrial, Atmospheric and Oceanic Sciences, Vol 24, Iss 3, p 393 (2013)
By using network observation of subionospheric VLF (very low frequency)/LF (low frequency) signals in Japan and in Russia, we have found a significant ionospheric perturbation prior to the recent 2011 March 11 Japan earthquake (EQ) which occurred at
Externí odkaz:
https://doaj.org/article/fe1c5da67ac54c1bad78db9fd2da2194
Autor:
Takayuki Takachi, Chansu Shin, Masaru Imamura, Yasushi Kasahara, Jirou Utsumi, Chihaya Imai, Akihiko Saitoh, Hirokazu Kanegane, Hiroshi Shimizu, Akiyoshi Kakita, Ryosuke Hosokai, Haruko Iwabuchi
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 8 (2020)
Frontiers in Pediatrics, Vol 8 (2020)
Chronic enteroviral meningoencephalitis is a well-known complication in patients with X-linked agammaglobulinemia (XLA). However, progressive neurodegenerative disorders or chronic neuroinflammatory diseases with no causative microorganisms have been
Autor:
Akihiko Saitoh, Yasushi Kasahara, Keichiro Mihara, Masaru Imamura, Chansu Shin, Haruko Iwabuchi, Nobuhiro Kubo, Takayuki Takachi, Chihaya Imai
Publikováno v:
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Objectives One of the reasons as to why chimeric antigen receptors (CAR)‐T cell therapy for malignancies other than CD19‐ or BCMA‐positive tumors has yet to produce remarkable progress is the paucity of targetable antigens. NKp44 is only expres
Autor:
Yasushi Kasahara
Publikováno v:
Groups of Diffeomorphisms: In honor of Shigeyuki Morita on the occasion of his 60th birthday, R. Penner, D. Kotschick, T. Tsuboi, N. Kawazumi, T. Kitano and Y. Mitsumatsu, eds. (Tokyo: Mathematical Society of Japan, 2008)
We consider the linear representations of the mapping class group of an n-punctured 2-sphere constructed by V. F. R. Jones using Iwahori-Hecke algebras of type A. We show that their faithfulness is equivalent to that of certain related Iwahori-Hecke
Autor:
Akihito Ishigami, Megumi Nakamura, Yoshiaki Uchida, Shuuichi Nakaya, Byungki Jang, Hirofumi Masutomi, Yong-Chul Jeon, Tosifusa Toda, Setsuko Handa, Yasushi Kasahara, Shigeo Murayama, Eun-Kyoung Choi, Yuko Saito, Naoki Maruyama, Yong-Sun Kim
Publikováno v:
Journal of Neuroscience Research. 93:1664-1674
Peptidylarginine deiminases (PADs) are posttranslational modification enzymes that convert protein arginine to citrulline residues in a calcium ion-dependent manner. Previously, we reported the abnormal accumulation of citrullinated proteins and the