Zobrazeno 1 - 10
of 521
pro vyhledávání: '"Yasushi ITO"'
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 34, Iss , Pp 100954- (2023)
Objective: We assessed the usefulness of flow cytometry as a functional assay to measure glucose transporter 1 (GLUT1) levels on the surface of red blood cells (RBCs) from Japanese patients with glucose transporter 1 deficiency syndrome (Glut1DS). Me
Externí odkaz:
https://doaj.org/article/495ddd75a6a546a493bf27d97577b7b6
Autor:
Jiefei Geng, Yasushi Ito, Linyu Shi, Palak Amin, Jiachen Chu, Amanda Tomie Ouchida, Adnan Kasim Mookhtiar, Heng Zhao, Daichao Xu, Bing Shan, Ayaz Najafov, Guangping Gao, Shizuo Akira, Junying Yuan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
TNFα can promote three distinct mechanisms of cell death: necroptosis, RIPK1-independent and dependent apoptosis. Here the authors show that TNFα-induced phosphorylation of RIPK1 in the intermediate domain by TAK1 plays a key role in regulating thi
Externí odkaz:
https://doaj.org/article/bebdf94e5c8e42219dc5cf8b4c649af2
Autor:
Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov, Yaoyang Zhang, Bing Shan, Judy Park DeWitt, Juanying Ye, Xumin Zhang, Ansi Chang, Helin Vakifahmetoglu-Norberg, Jiefei Geng, Benedicte Py, Wen Zhou, Palak Amin, Jonilson Berlink Lima, Chunting Qi, Qiang Yu, Bruce Trapp, Junying Yuan
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1836-1849 (2015)
Multiple sclerosis (MS), a common neurodegenerative disease of the CNS, is characterized by the loss of oligodendrocytes and demyelination. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine implicated in MS, can activate necroptosis, a ne
Externí odkaz:
https://doaj.org/article/0178a95c3a344ac1b03cbe265055d0cc
Autor:
Yasushi Ito, Mitsunori Yamada, Hirotaka Tanaka, Kazunari Aida, Kazuhiro Tsuruma, Masamitsu Shimazawa, Isao Hozumi, Takashi Inuzuka, Hitoshi Takahashi, Hideaki Hara
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 3, Pp 470-476 (2009)
Endoplasmic reticulum (ER) stress-induced neuronal death may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, whether CCAAT/enhancer binding protein (C/EBP) homologous protein (CHOP), an ER-stress apoptotic me
Externí odkaz:
https://doaj.org/article/ab36a4d3926d41d5b73d9632bcae6bab
Autor:
Yasushi Ito, Masamitsu Shimazawa, Yukihiro Akao, Yoshimi Nakajima, Norio Seki, Yoshinori Nozawa, Hideaki Hara
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 196-204 (2006)
Lig-8, a lignophenol derivative from bamboo lignin, potently suppresses oxidative stress-induced apoptosis. Here, we first examined in vitro whether lig-8 protects against neuronal damage induced by oxygen-glucose deprivation (OGD) followed by reoxyg
Externí odkaz:
https://doaj.org/article/8bf180a682b24a55be9ceb6959881a4e
Autor:
Masamitsu Shimazawa, Yasushi Ito, Yuta Inokuchi, Hajime Yamanaka, Tomohiro Nakanishi, Takuya Hayashi, Bin Ji, Makoto Higuchi, Tetsuya Suhara, Kazuyuki Imamura, Makoto Araie, Yasuyoshi Watanabe, Hirotaka Onoe, Hideaki Hara
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30526 (2012)
We examined lateral geniculate nucleus (LGN) degeneration as an indicator for possible diagnosis of glaucoma in experimental glaucoma monkeys using positron emission tomography (PET). Chronic intraocular pressure (IOP) elevation was induced by laser
Externí odkaz:
https://doaj.org/article/ccfa098a1e034da98bd8c78563f1cf9a
Autor:
Masamitsu Shimazawa, Hirotaka Tanaka, Yasushi Ito, Nobutaka Morimoto, Kazuhiro Tsuruma, Michinori Kadokura, Shigeki Tamura, Teruyoshi Inoue, Mitsunori Yamada, Hitoshi Takahashi, Hitoshi Warita, Masashi Aoki, Hideaki Hara
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15307 (2010)
Amyotrophic lateral sclerosis (ALS) is the most frequent adult-onset motor neuron disease, and recent evidence has suggested that endoplasmic reticulum (ER) stress signaling is involved in the pathogenesis of ALS. Here we identified a small molecule,
Externí odkaz:
https://doaj.org/article/2aee30f506154b3f9a2ac9642e893488
Autor:
Yasushi Ito, Mitsuhiro Murayama, Yuzuru Yokokawa, Kazuomi Yamamoto, Kentaro Tanaka, Tohru Hirai
Publikováno v:
Journal of Aircraft. 59:1281-1302
形態: カラー図版あり
Physical characteristics: Original contains color illustrations
Accepted: 2022-03-10
PA2220036000
Physical characteristics: Original contains color illustrations
Accepted: 2022-03-10
PA2220036000
Publikováno v:
Mindfulness. 13:1458-1468
Objectives As mindfulness practices become mainstream, it is increasingly common for participants in mindfulness-based interventions (MBI) to have previous meditation experience. The primary aim of this study was to assess whether the impacts of a mi
Autor:
Hanae MATSUMOTO, Yasushi ITO
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 83:1211-1215