Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Yasushi Honma"'
2
ChemInform Abstract: 2-((2-Aminobenzyl)sulfinyl)-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent( d)imidazoles as a Novel Class of Gastric H+/K+-ATPase Inhibitors
Autor: Takeshi Yura, Mine Kinoshita, Masaki Yamada, Masamichi Morimoto, Masaki Sugiura, Yasushi Honma, Tsunehiro Harada, Koichiro Yamada
Publikováno v: ChemInform. 27
Substituted 2-sulfinylimidazoles were synthesized and investigated as potential inhibitors of gastric H+/K+-ATPase. The 4,5-unsubstituted imidazole series 6−11 and the 1,4,5,6-tetrahydrocyclopent[d]imidazole series 12 were found to be potent inhibi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af4f8b5a61ede7ab4d9797e84b32f22f
https://doi.org/10.1002/chin.199619135
Zobrazit plný text záznamu
3
2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d]imidazoles as a novel class of gastric H+/K+-ATPase inhibitors
Autor: Tsunehiro Harada, Takeshi Yura, Koichiro Yamada, Masamichi Morimoto, Masaki Sugiura, Mine Kinoshita, Yasushi Honma, Masaki Yamada
Publikováno v: Journal of medicinal chemistry. 39(2)
Substituted 2-sulfinylimidazoles were synthesized and investigated as potential inhibitors of gastric H+/K(+)-ATPase. The 4,5-unsubstituted imidazole series 6-11 and the 1,4,5,6-tetrahydrocyclopent[d]imidazole series 12 were found to be potent inhibi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3d7b50e1fa873b34f2b36cb94eaa51
https://pubmed.ncbi.nlm.nih.gov/8558532
Zobrazit plný text záznamu
4
Synthesis of N-substituted C-normorphinans and their pharmacological properties
Autor: Hirozumi Inoue, Michio Yamamura, Tadamasa Date, Katsuyuki Noguchi, Kimio Okamura, Seiichi Nurimoto, Yasushi Honma, Seiichi Saito, Mikio Takeda
Publikováno v: Chemicalpharmaceutical bulletin. 40(5)
Several N-substituted C-normorphinans (VIII and IX) were synthesized and tested for their analgetic and narcotic antagonist activities and physical dependence capacity. Treatment of N-formyl- octahydro-2-pyrindine (IIIc) with polyphosphoric acid read
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6ed0af9b785dd6aaca1bbd38f77aab
https://pubmed.ncbi.nlm.nih.gov/1394632
Zobrazit plný text záznamu
5
Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. II. 2-(Phenylpiperazinoalkoxyphenyl)thiazolidine-3-thiocarboxamides and the corresponding carboxamides
Autor: Hisao Ohtsuka, Taku Nagao, Kuniyuki Oda, Yutaka Hino, Hiroshi Wada, Mikio Takeda, Akira Tsunashima, Hideo Nakai, Hiroyuki Nate, Yasuo Sekine, Kenji Matsuki, Akihiko Ishida, Yasushi Honma, Hideo Yabana
Publikováno v: Chemical and Pharmaceutical Bulletin. 35:2394-2411
A large number of 2- (phenylpiperazinoalkoxyphenyl) thiazolidine-3-thiocarboxamides and the corresponding carboxamides (II) were synthesized and tested for inotropic activity in anesthetized dogs. Compounds II were prepared from a hydroxybenzaldehyde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec579477778107da100837e02bbde17
https://doi.org/10.1248/cpb.35.2394
Zobrazit plný text záznamu
6
Azabicycloalkanes as analgetics. II. An improved synthesis of 1-phenyl-6-azabicyclo(3,2,1)octane derivatives
Autor: Seiichi Saito, Masatoshi Kawamori, Yasushi Honma, H. Inoue, Mikio Takeda, Katsuyuki Noguchi, Goro Tsukamoto, Yasuhiko Yamawaki
Publikováno v: Chemical and Pharmaceutical Bulletin. 24:1514-1526
An improved synthesis of 6, 7endo-dimethyl-1-(3-hydroxyphenyl)-6-azabicyclo [3, 2, 1]-octane (10c), a new analgetic agent with a low addiction liability, is described. Grignard reaction of 3-ethoxy-2-cyclohexen-1-one (1) with m-methoxyphenylmagnesium
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fd758e73dd228c276ce873d84efda61
https://doi.org/10.1248/cpb.24.1514
Zobrazit plný text záznamu
8
Antiallergic agents. 2. N-(1H-Tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides
Autor: Kyoji Hanamoto, T. Hashiyama, Yasushi Honma, Mikio Takeda, Akihiko Ishida, Hiroshi Inoue, Yasutoshi Ono, Hideo Nakai, Kuniyuki Oda, Kei Tsuzurahara
Publikováno v: Journal of Medicinal Chemistry. 26:1499-1504
A new series of N-(1H-tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides was prepared to determine the effects of substituents on the benzene and pyridine rings on antiallergic activity in the rat passive cutaneous anaphylaxis (PCA) assay after oral admi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef2f777fce29410bcfa5369a2ae3330
https://doi.org/10.1021/jm00364a026
Zobrazit plný text záznamu
9
Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. I. 2-Phenylthiazolidine-3-thiocarboxamides
Autor: Taku Nagao, Hiroshi Wada, Yasuo Sekine, Mikio Takeda, Hideo Nakai, Hiroyuki Nate, Hideo Yabana, Yasushi Honma
Publikováno v: Chemical and Pharmaceutical Bulletin. 35:1953-1968
A series of novel 2-phenylthiazolidine-3-thiocarboxamides (II) was synthesized and tested for positive inotropic activity in the isolated guinea pig heart and in anesthetized dogs. Reaction of the benzaldehydes (VI, XI, XIV and XV) with cysteamine fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03332a58854a5159a222e624e579913c
https://doi.org/10.1248/cpb.35.1953
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje