Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasushi Aozuka"'
Publikováno v:
YAKUGAKU ZASSHI. 131:1241-1250
Hot flash (HF) is the most common phenomenon in climacteric symptoms which often develop concomitantly with a decrease in estrogen in postmenopausal women. The onset mechanism of the hot flash is complicated and remains unclear. To date, some animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d309824e5ce43f50225d364a33a06836
https://doi.org/10.1248/yakushi.131.1241
https://doi.org/10.1248/yakushi.131.1241
Autor:
Yasuji, Ueda, Takehiro, Yamagishi, Kazunori, Samata, Noriko, Hirayama, Yasushi, Aozuka, Makoto, Tanaka, Shiro, Nakaike, Ikuo, Saiki
Publikováno v:
Anticancer research. 25(6B)
Vascular endothelial growth factor (VEGF) plays key roles in tumor angiogenesis. Therefore, VEGF and its receptors are considered to be primary targets for antiangiogenic strategy during cancer chemotherapy. Our previous study reported that VGA1155,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6184c6cea733d33cc870172598ad017a
https://pubmed.ncbi.nlm.nih.gov/16309186
https://pubmed.ncbi.nlm.nih.gov/16309186
Autor:
Ikuo Saiki, Keiko Sekine, Masatoshi Yamada, Yasushi Aozuka, Kiyohiro Nishikawa, Hideji Fujii, Kazuteru Fukasawa, Keiichi Koizumi, Yurika Saitoh
Publikováno v:
Cancer letters. 243(1)
Proteolytic enzyme-mediated degradation of the extracellular matrix (ECM) is crucial for the formation of both tumor metastasis and angiogenesis. Recently, several reports have suggested that aminopeptidases are involved in this process, but precisel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9669afbdf6a4aec0d82d3cd6e4b9fd62
https://pubmed.ncbi.nlm.nih.gov/16466852
https://pubmed.ncbi.nlm.nih.gov/16466852
Autor:
Isaku, Yoshioka, Yasunori, Tsuchiya, Yasushi, Aozuka, Yasuharu, Onishi, Hiroaki, Sakurai, Keiichi, Koizumi, Kazuhiro, Tsukada, Ikuo, Saiki
Publikováno v:
Anticancer research. 25(2A)
Recently, we have reported that surgical stress promoted the metastasis of murine colon carcinoma cells to the lung by inducing the expression of proteases such as matrix metalloprotease-9 (MMP-9) in lung tissue. Urinary trypsin inhibitor (UTI) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad4e69eee9c3edaf5a5abbf7d8a0943e
https://pubmed.ncbi.nlm.nih.gov/15868913
https://pubmed.ncbi.nlm.nih.gov/15868913
Autor:
Yasuji, Ueda, Takehiro, Yamagishi, Hisao, Ikeya, Noriko, Hirayama, Takashi, Itokawa, Yasushi, Aozuka, Kazunori, Samata, Shiro, Nakaike, Makoto, Tanaka, Mayumi, Ono, Ikuo, Saiki
Publikováno v:
Anticancer research. 24(5A)
The process of angiogenesis involves the formation of new blood vessels from established vasculature and is essential for progressive tumor growth and metastasis. Since vascular endothelial growth factor (VEGF) plays a pivotal role in tumor angiogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ec95d60c590745ecfb04298ecb3d853
https://pubmed.ncbi.nlm.nih.gov/15517909
https://pubmed.ncbi.nlm.nih.gov/15517909
Autor:
Pattama Singhirunnusorn, Yurika Saitoh, Yasushi Aozuka, Ikuo Saiki, Hiroaki Sakurai, Somsak Ruchirawat, Noritaka Kawasaki, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Min-Kyung Choo
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 25(1)
Vanillin, a food flavoring agent, has been reported to show anti-mutagenic activity and to inhibit chemical carcinogenesis. In this study, we examined the effect of vanillin on the growth and metastasis of 4T1 mammary adenocarcinoma cells in BALB/c m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1560c6db137113cb76030f99baa6bef8
https://pubmed.ncbi.nlm.nih.gov/15854801
https://pubmed.ncbi.nlm.nih.gov/15854801
Publikováno v:
Cancer letters. 216(1)
We investigated the effect of bestatin, an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B, on the angiogenesis induced by B16-BL6 melanoma cells. Oral administration of bestatin (100-200 mg/kg/day) was found to significantly inhibit th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0ceb356ee3d35199807a9b72356126
https://pubmed.ncbi.nlm.nih.gov/15500947
https://pubmed.ncbi.nlm.nih.gov/15500947
Autor:
Yoshinori Doki, Keiichi Koizumi, Eliane Shizuka Nakamura, Takuro Misaki, Hiroaki Sakurai, Ikuo Saiki, Katsuyuki Ichiki, Yasushi Aozuka, Yasukata Ohashi, Yoko Kozawa
Publikováno v:
Scopus-Elsevier
To develop new therapy strategies for lung cancer, we established an animal model, which reflects the clinical features of mediastinal lymph node metastasis of lung cancer. This study was designed to determine whether CCL21 induced biological functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e3dc13424372f7b95ac20043f91f66
http://www.scopus.com/inward/record.url?eid=2-s2.0-34548043502&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-34548043502&partnerID=MN8TOARS
